首页 期刊 论文 学科刊群 资讯 加盟 关于
EN
image
Article(id=1241329581752373615, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241329570129956900, articleNumber=null, orderNo=null, doi=10.20043/j.cnki.MPM.202501374, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1737475200000, receivedDateStr=2025-01-22, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1773885635078, onlineDateStr=2026-03-19, pubDate=1752076800000, pubDateStr=2025-07-10, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1773885635078, onlineIssueDateStr=2026-03-19, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1773885635078, creator=13701087609, updateTime=1773885635078, updator=13701087609, issue=Issue{id=1241329570129956900, tenantId=1146029695717560320, journalId=1227665162245664772, year='2025', volume='52', issue='13', pageStart='2305', pageEnd='2496', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1773885632307, creator=13701087609, updateTime=1773885763730, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1241330121425080472, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241329570129956900, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1241330121425080473, tenantId=1146029695717560320, journalId=1227665162245664772, issueId=1241329570129956900, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=2466, endPage=2470, ext={EN=ArticleExt(id=1241329582666731910, articleId=1241329581752373615, tenantId=1146029695717560320, journalId=1227665162245664772, language=EN, title=Knowledge and attitudes toward latent tuberculosis infection and preventive treatment among tuberculosis control workers in Xinjiang, columnId=1228016573156360233, journalTitle=Modern Preventive Medicine, columnName=Disease Control and Prevention, runingTitle=null, highlight=null, articleAbstract=
Objective

To investigate the knowledge and attitudes of tuberculosis (TB) control workers regarding preventive treatment for latent tuberculosis infection (LTBI) in Xinjiang Uygur Autonomous Region, providing evidence for promoting LTBI preventive treatment.

Methods

A cross-sectional survey was conducted among TB control workers from 14 prefectures in Xinjiang. Data were entered using EpiData 3.1 and analyzed with SPSS 26.0, with statistical significance set at P<0.05.

Results

Among 235 respondents,92.77% (218/235) knew about LTBI, 63.40% (149/235) understood the probability of LTBI progression, 73.62% (173/235) knew screening methods, 29.79% (70/235) recognized high-risk populations, 65.11% (153/235) knew target groups for preventive treatment, and 60.85% (143/235) understood treatment efficacy. Of those aware of LTBI, 71.56% (156/218) believed preventive treatment was necessary. Significant differences (P<0.05) were found in recommending preventive treatment by gender (χ2=4.565, P=0.033), occupation (χ2=10.839, P=0.004), knowledge of treatment efficacy (χ2=16.490, P<0.001), perceived necessity (χ2=122.919, P<0.001), and training experience (χ2=5.200, P=0.023). Main concerns included uncertain efficacy (39.57%), adverse reactions (32.34%), public knowledge gaps (15.32%), and implementation difficulties (12.77%).

Conclusion

TB control workers demonstrated limited knowledge and moderate acceptance of LTBI preventive treatment. Targeted training and education programs are needed to improve acceptance and implementation of preventive treatment among high-risk populations.

, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, authorCompany=null, fund=null, authors=null, authorsList=WUFUER Ke-di-er-ye-zi-ke-zi, Sen-lu WANG, Tao HUANG, Nian-qiang LIU, JINYISI Jia-yi-na-ti, BADEERHAN Gu-li-na, Xin-qi WANG), CN=ArticleExt(id=1241329583115522462, articleId=1241329581752373615, tenantId=1146029695717560320, journalId=1227665162245664772, language=CN, title=新疆结核病防治人员对结核潜伏感染及结核病预防性治疗的认知态度分析, columnId=1228016573844226129, journalTitle=现代预防医学, columnName=疾病预防控制, runingTitle=null, highlight=null, articleAbstract=
目的

探讨新疆维吾尔自治区（简称新疆）结核病防治人员对结核潜伏感染（latent tuberculosis infection, LTBI）者进行结核病预防性治疗的认知态度，旨在为促进结核病预防性治疗工作的推进提供科学依据。

方法

对新疆14个地州疾控机构和结核病定点医疗机构结核病防治人员进行调查。采用EpiData 3.1软件进行问卷数据录入，使用SPSS 26.0软件对收集的数据进行统计分析，以P<0.05为差异有统计学意义。

结果

92.77%（218/235）的防治人员知晓LTBI，63.40%（149/235）知晓LTBI发病概率，73.62%（173/235）对LTBI筛查方法知晓，29.79%（70/235）对LTBI高危人群知晓，65.11%（153/235）的防治人员对LTBI预防性治疗目标人群知晓，60.85%（143/235）清楚预防性治疗的效果。在知晓LTBI的防治人员中，71.56%（156/218）的防治人员认为有必要对LTBI者开展预防性治疗。不同性别（χ2=4.565，P=0.033）、不同职业类别（χ2=10.839，P=0.004）、是否知晓预防性治疗效果（χ2=16.490，P<0.001）、是否认为有必要对LTBI者开展预防性治疗（χ2=122.919，P<0.001）、是否参加过LTBI相关培训（χ2=5.200，P=0.023）在是否对LTBI者推荐预防性治疗之间比较，差异有统计学意义。“担心预防性治疗效果不明确”“担心预防性治疗会产生不良反应”“担心LTBI相关宣传较少，群众知识缺乏”“担心工作难度大，LTBI者不配合，难以开展”是医务人员对LTBI者开展预防性治疗主要担忧的问题。

结论

结核病防治人员对LTBI相关知识知晓情况以及对预防性治疗接受意愿均不高，应开展有针对性的培训和宣传教育活动，提高其对预防性治疗的接受度，以推动重点人群结核病预防性治疗工作的开展。

, correspAuthors=null, authorNote=null, correspAuthorsNote=
王新旗，E-mail:
, copyrightStatement=本刊刊出的所有文章不代表中华预防医学会和本刊编委会的观点，除非特别声明。, copyrightOwner=中华预防医学会和四川大学华西公共卫生学院, extLink=null, articleAbsUrl=null, sourceXml=ZV0XeepuOW2zWHMhG3yayA==, magXml=VuyPQfDRppHZJH6NVWfp+Q==, pdfUrl=null, pdf=3EOFGZmwS9pDwSNQ/avFBA==, pdfFileSize=630021, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=ueSbKdca9k3PMpOUmGEwpg==, mapNumber=null, authorCompany=null, fund=null, authors=

克地尔叶克孜·吾甫尔与王森路为共同第一作者

克地尔叶克孜·吾甫尔（1999—），女，硕士在读，研究方向：公共卫生专业;

王森路（1987—），男，博士在读，研究方向：结核病防治；

, authorsList=克地尔叶克孜·吾甫尔, 王森路, 黄涛, 刘年强, 加依那提·金格斯, 古丽娜·巴德尔汗, 王新旗)}, authors=[Author(id=1241329761763512785, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1241329761893536221, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, authorId=1241329761763512785, language=EN, stringName=WUFUER Ke-di-er-ye-zi-ke-zi, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=1, address=School of Public Health, Xinjiang Medical University, Urumqi, Xinjiang 830017, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1241329761994199526, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, authorId=1241329761763512785, language=CN, stringName=克地尔叶克孜·吾甫尔, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=1, address=1.新疆医科大学公共卫生学院，新疆 乌鲁木齐 830017, bio={"content":"

克地尔叶克孜·吾甫尔（1999—），女，硕士在读，研究方向：公共卫生专业;

"}, bioImg=null, bioContent=

克地尔叶克孜·吾甫尔（1999—），女，硕士在读，研究方向：公共卫生专业;

, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1241329761398608313, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, xref=1., ext=[AuthorCompanyExt(id=1241329761402802619, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, companyId=1241329761398608313, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=School of Public Health, Xinjiang Medical University, Urumqi, Xinjiang 830017, China), AuthorCompanyExt(id=1241329761415385532, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, companyId=1241329761398608313, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=1.新疆医科大学公共卫生学院，新疆 乌鲁木齐 830017)])]), Author(id=1241329762107445743, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, orderNo=1, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1241329762216497657, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, authorId=1241329762107445743, language=EN, stringName=Sen-lu WANG, firstName=Sen-lu, middleName=null, lastName=WANG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=1, 2, address=School of Public Health, Xinjiang Medical University, Urumqi, Xinjiang 830017, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1241329762321355268, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, authorId=1241329762107445743, language=CN, stringName=王森路, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=1, 2, address=1.新疆医科大学公共卫生学院，新疆 乌鲁木齐 830017
2.新疆维吾尔自治区疾病预防控制中心，新疆 乌鲁木齐 830002, bio={"content":"

王森路（1987—），男，博士在读，研究方向：结核病防治；

"}, bioImg=null, bioContent=

王森路（1987—），男，博士在读，研究方向：结核病防治；

, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1241329761398608313, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, xref=1., ext=[AuthorCompanyExt(id=1241329761402802619, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, companyId=1241329761398608313, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=School of Public Health, Xinjiang Medical University, Urumqi, Xinjiang 830017, China), AuthorCompanyExt(id=1241329761415385532, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, companyId=1241329761398608313, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=1.新疆医科大学公共卫生学院，新疆 乌鲁木齐 830017)]), AuthorCompany(id=1241329761549603270, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, xref=2., ext=[AuthorCompanyExt(id=1241329761599934924, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, companyId=1241329761549603270, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=2.新疆维吾尔自治区疾病预防控制中心，新疆 乌鲁木齐 830002)])]), Author(id=1241329762442990093, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, orderNo=2, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1241329762593985051, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, authorId=1241329762442990093, language=EN, stringName=Tao HUANG, firstName=Tao, middleName=null, lastName=HUANG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=1, address=School of Public Health, Xinjiang Medical University, Urumqi, Xinjiang 830017, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1241329762837254697, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, authorId=1241329762442990093, language=CN, stringName=黄涛, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=1, address=1.新疆医科大学公共卫生学院，新疆 乌鲁木齐 830017, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1241329761398608313, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, xref=1., ext=[AuthorCompanyExt(id=1241329761402802619, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, companyId=1241329761398608313, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=School of Public Health, Xinjiang Medical University, Urumqi, Xinjiang 830017, China), AuthorCompanyExt(id=1241329761415385532, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, companyId=1241329761398608313, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=1.新疆医科大学公共卫生学院，新疆 乌鲁木齐 830017)])]), Author(id=1241329762963083830, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, orderNo=3, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1241329763063747139, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, authorId=1241329762963083830, language=EN, stringName=Nian-qiang LIU, firstName=Nian-qiang, middleName=null, lastName=LIU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=2, address=null, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1241329763151827534, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, authorId=1241329762963083830, language=CN, stringName=刘年强, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=2, address=2.新疆维吾尔自治区疾病预防控制中心，新疆 乌鲁木齐 830002, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1241329761549603270, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, xref=2., ext=[AuthorCompanyExt(id=1241329761599934924, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, companyId=1241329761549603270, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=2.新疆维吾尔自治区疾病预防控制中心，新疆 乌鲁木齐 830002)])]), Author(id=1241329763302822488, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, orderNo=4, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1241329763432845926, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, authorId=1241329763302822488, language=EN, stringName=JINYISI Jia-yi-na-ti, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=1, address=School of Public Health, Xinjiang Medical University, Urumqi, Xinjiang 830017, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1241329763558675057, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, authorId=1241329763302822488, language=CN, stringName=加依那提·金格斯, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=1, address=1.新疆医科大学公共卫生学院，新疆 乌鲁木齐 830017, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1241329761398608313, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, xref=1., ext=[AuthorCompanyExt(id=1241329761402802619, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, companyId=1241329761398608313, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=School of Public Health, Xinjiang Medical University, Urumqi, Xinjiang 830017, China), AuthorCompanyExt(id=1241329761415385532, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, companyId=1241329761398608313, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=1.新疆医科大学公共卫生学院，新疆 乌鲁木齐 830017)])]), Author(id=1241329763667726972, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, orderNo=5, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1241329763801944710, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, authorId=1241329763667726972, language=EN, stringName=BADEERHAN Gu-li-na, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=2, address=null, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1241329763936162449, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, authorId=1241329763667726972, language=CN, stringName=古丽娜·巴德尔汗, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=2, address=2.新疆维吾尔自治区疾病预防控制中心，新疆 乌鲁木齐 830002, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1241329761549603270, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, xref=2., ext=[AuthorCompanyExt(id=1241329761599934924, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, companyId=1241329761549603270, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=2.新疆维吾尔自治区疾病预防控制中心，新疆 乌鲁木齐 830002)])]), Author(id=1241329764061991575, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, orderNo=6, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=1332830684@qq.com, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1241329764175237795, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, authorId=1241329764061991575, language=EN, stringName=Xin-qi WANG, firstName=Xin-qi, middleName=null, lastName=WANG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=1, 2, address=School of Public Health, Xinjiang Medical University, Urumqi, Xinjiang 830017, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1241329764288484013, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, authorId=1241329764061991575, language=CN, stringName=王新旗, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=1, 2, address=1.新疆医科大学公共卫生学院，新疆 乌鲁木齐 830017
2.新疆维吾尔自治区疾病预防控制中心，新疆 乌鲁木齐 830002, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1241329761398608313, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, xref=1., ext=[AuthorCompanyExt(id=1241329761402802619, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, companyId=1241329761398608313, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=School of Public Health, Xinjiang Medical University, Urumqi, Xinjiang 830017, China), AuthorCompanyExt(id=1241329761415385532, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, companyId=1241329761398608313, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=1.新疆医科大学公共卫生学院，新疆 乌鲁木齐 830017)]), AuthorCompany(id=1241329761549603270, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, xref=2., ext=[AuthorCompanyExt(id=1241329761599934924, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, companyId=1241329761549603270, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=2.新疆维吾尔自治区疾病预防控制中心，新疆 乌鲁木齐 830002)])])], keywords=[Keyword(id=1241329764473033403, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, language=EN, orderNo=1, keyword=Latent tuberculosis infection), Keyword(id=1241329764586279621, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, language=EN, orderNo=2, keyword=Preventive treatment), Keyword(id=1241329764733080270, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, language=EN, orderNo=3, keyword=Tuberculosis control workers), Keyword(id=1241329764833743570, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, language=EN, orderNo=4, keyword=Knowledge and attitudes), Keyword(id=1241329764938601181, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, language=CN, orderNo=1, keyword=结核潜伏感染), Keyword(id=1241329765064430312, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, language=CN, orderNo=2, keyword=预防性治疗), Keyword(id=1241329765198648048, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, language=CN, orderNo=3, keyword=结核病防治人员), Keyword(id=1241329765328671484, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, language=CN, orderNo=4, keyword=认知态度)], refs=[Reference(id=1241329766700208990, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2021, volume=11, issue=9, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[1], rfOrder=0, authorNames=Bar-Meir M, Pariente G, Romem A, journalName=BMJ Open, refType=null, unstructuredReference=Bar-Meir M, Pariente G, Romem A, et al. Identifying factors affecting latent tuberculosis treatment acceptance among healthcare workers: a retrospective analysis in a tertiary care centre[J] . BMJ Open, 2021, 11(9): e047444., articleTitle=Identifying factors affecting latent tuberculosis treatment acceptance among healthcare workers: a retrospective analysis in a tertiary care centre, refAbstract=null), Reference(id=1241329766796677990, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2023, volume=45, issue=8, pageStart=723, pageEnd=727, url=null, language=null, rfNumber=[2], rfOrder=1, authorNames=郭同磊, 辛赫男, 高磊, journalName=中国防痨杂志, refType=null, unstructuredReference=郭同磊， 辛赫男， 高磊.《世界卫生组织结核病整合指南模块1:结核病预防性治疗》解读[J] .中国防痨杂志，2023，45（8）：723-727., articleTitle=《世界卫生组织结核病整合指南模块1:结核病预防性治疗》解读, refAbstract=null), Reference(id=1241329766930895728, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2023, volume=45, issue=8, pageStart=723, pageEnd=727, url=null, language=null, rfNumber=[2], rfOrder=2, authorNames=Guo TL, Xin HN, Gao L, journalName=Chinese Journal of Antituberculosis, refType=null, unstructuredReference=Guo TL, Xin HN, Gao L. Interpretation of WHO consolidated guidelines on tuberculosis: Module 1: prevention: tuberculosis preventive treatment[J] .Chinese Journal of Antituberculosis, 2023, 45(8): 723-727.(In Chinese), articleTitle=Interpretation of WHO consolidated guidelines on tuberculosis: Module 1: prevention: tuberculosis preventive treatment, refAbstract=null), Reference(id=1241329767018976121, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2021, volume=43, issue=9, pageStart=874, pageEnd=878, url=null, language=null, rfNumber=[3], rfOrder=3, authorNames=周林, 初乃惠, 陆伟, journalName=中国防痨杂志, refType=null, unstructuredReference=周林， 初乃惠， 陆伟.高危人群结核分枝杆菌潜伏感染检测及预防性治疗专家共识[J] .中国防痨杂志，2021，43（9）：874-878., articleTitle=高危人群结核分枝杆菌潜伏感染检测及预防性治疗专家共识, refAbstract=null), Reference(id=1241329767153193856, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2021, volume=43, issue=9, pageStart=874, pageEnd=878, url=null, language=null, rfNumber=[3], rfOrder=4, authorNames=Zhou L, Chu NH, Lu W, journalName=Chinese Journal of Antituberculosis, refType=null, unstructuredReference=Zhou L, Chu NH, Lu W. Expert consensus on detection and preventive treatment of latent infection of Mycobacterium tuberculosis in high-risk populations[J] . Chinese Journal of Antituberculosis, 2021, 43(9): 874-878.(In Chinese), articleTitle=Expert consensus on detection and preventive treatment of latent infection of Mycobacterium tuberculosis in high-risk populations, refAbstract=null), Reference(id=1241329767241274243, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2024, volume=59, issue=2, pageStart=274, pageEnd=279, url=null, language=null, rfNumber=[4], rfOrder=5, authorNames=余海茹, 闫晔鑫, 杨娇, journalName=郑州大学学报:医学版, refType=null, unstructuredReference=余海茹，闫晔鑫，杨娇，等.2004至2021年中国肺结核发病趋势及空间分布特征[J] .郑州大学学报:医学版，2024，59（2）：274-279., articleTitle=2004至2021年中国肺结核发病趋势及空间分布特征, refAbstract=null), Reference(id=1241329767354520458, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2024, volume=59, issue=2, pageStart=274, pageEnd=279, url=null, language=null, rfNumber=[4], rfOrder=6, authorNames=Yu HR, Yan YX, Yang J, journalName=Journal of Zhengzhou University(Medical Sciences), refType=null, unstructuredReference=Yu HR, Yan YX, Yang J, et al. Incidence trend and spatial distribution characteristic of pulmonary tuberculosis in China from 2004 to 2021[J] .Journal of Zhengzhou University(Medical Sciences), 2024, 59(2): 274-279.(In Chinese), articleTitle=Incidence trend and spatial distribution characteristic of pulmonary tuberculosis in China from 2004 to 2021, refAbstract=null), Reference(id=1241329767425823631, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2024, volume=46, issue=2, pageStart=141, pageEnd=144, url=null, language=null, rfNumber=[5], rfOrder=7, authorNames=王森路, 刘年强, 王新旗, journalName=中国防痨杂志, refType=null, unstructuredReference=王森路，刘年强，王新旗，等.结核病防治“新疆模式”的发展及成效[J] .中国防痨杂志，2024，46（2）：141-144., articleTitle=结核病防治“新疆模式”的发展及成效, refAbstract=null), Reference(id=1241329767509709717, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2024, volume=46, issue=2, pageStart=141, pageEnd=144, url=null, language=null, rfNumber=[5], rfOrder=8, authorNames=Wang SL, Liu NQ, Wang XQ, journalName=Chinese Journal of Antituberculosis, refType=null, unstructuredReference=Wang SL, Liu NQ, Wang XQ, et al. Development and effectiveness of"Xinjiang Model" for tuberculosis prevention and control[J] . Chinese Journal of Antituberculosis, 2024, 46(2): 141-144.(In Chinese), articleTitle=Development and effectiveness of"Xinjiang Model" for tuberculosis prevention and control, refAbstract=null), Reference(id=1241329767660704669, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2022, volume=4, issue=11, pageStart=211, pageEnd=215, url=null, language=null, rfNumber=[6], rfOrder=9, authorNames=Fa LF, Xu CH, Cheng J, journalName=China CDC Wkly, refType=null, unstructuredReference=Fa LF, Xu CH, Cheng J, et al.Acceptability of tuberculosis preventive treatment strategies among healthcare workers using an online survey - China, 2021[J] . China CDC Wkly, 2022, 4(11): 211-215., articleTitle=Acceptability of tuberculosis preventive treatment strategies among healthcare workers using an online survey - China, 2021, refAbstract=null), Reference(id=1241329767765562278, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2020, volume=47, issue=9, pageStart=1647, pageEnd=1650, 1669, url=null, language=null, rfNumber=[7], rfOrder=10, authorNames=雷蓉蓉, 刘英, 张婷, journalName=现代预防医学, refType=null, unstructuredReference=雷蓉蓉，刘英，张婷，等.重庆市结核病防治医务人员结核潜伏感染及预防性治疗的认知态度分析[J] .现代预防医学，2020，47（9）：1647-1650, 1669., articleTitle=重庆市结核病防治医务人员结核潜伏感染及预防性治疗的认知态度分析, refAbstract=null), Reference(id=1241329767945917358, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2020, volume=47, issue=9, pageStart=1647, pageEnd=1650, 1669, url=null, language=null, rfNumber=[7], rfOrder=11, authorNames=Lei RR, Liu Y, Zhang T, journalName=Modern Preventive Medicine, refType=null, unstructuredReference=Lei RR, Liu Y, Zhang T, et al. Analysis of cognitive attitudes toward latent tuberculosis infection and prophylactic treatment among medical personnel for tuberculosis control in Chongqing[J] . Modern Preventive Medicine,2020, 47(9): 1647-1650, 1669.(In Chinese), articleTitle=Analysis of cognitive attitudes toward latent tuberculosis infection and prophylactic treatment among medical personnel for tuberculosis control in Chongqing, refAbstract=null), Reference(id=1241329768088523704, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2024, volume=38, issue=7, pageStart=63, pageEnd=66, url=null, language=null, rfNumber=[8], rfOrder=12, authorNames=姚晶, 李智红, 张怀庆, journalName=中国初级卫生保健, refType=null, unstructuredReference=姚晶，李智红，张怀庆，等.上海市静安区肺结核患者家庭内儿童青少年密接结核感染筛查情况及医务人员态度调查[J] .中国初级卫生保健，2024，38（7）：63-66., articleTitle=上海市静安区肺结核患者家庭内儿童青少年密接结核感染筛查情况及医务人员态度调查, refAbstract=null), Reference(id=1241329770194064319, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2024, volume=38, issue=7, pageStart=63, pageEnd=66, url=null, language=null, rfNumber=[8], rfOrder=13, authorNames=Yao J, Li ZH, Zhang HQ, journalName=Chinese Primary Health Care, refType=null, unstructuredReference=Yao J, Li ZH, Zhang HQ, et al. Screening of latent infection in close contacts of children and adolescents in families of pulmonary tuberculosis patients in Jing'an district and study on attitudes of medical staff[J] .Chinese Primary Health Care, 2024, 38(7): 63-66.(In Chinese), articleTitle=Screening of latent infection in close contacts of children and adolescents in families of pulmonary tuberculosis patients in Jing'an district and study on attitudes of medical staff, refAbstract=null), Reference(id=1241329770349253572, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2020, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[9], rfOrder=14, authorNames=World Health Organization, journalName=null, refType=null, unstructuredReference=World Health Organization. WHO consolidated guidelines on tuberculosis: Module 1: tuberculosis preventive treatment[R] .Geneva: World Health Organization, 2020., articleTitle=WHO consolidated guidelines on tuberculosis: Module 1: tuberculosis preventive treatment, refAbstract=null), Reference(id=1241329770496054216, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[10], rfOrder=15, authorNames=中华人民共和国国家卫生健康委员会, journalName=null, refType=null, unstructuredReference=中华人民共和国国家卫生健康委员会.中国结核病预防控制工作技术规范[EB/OL] .[2025-05-10] . http://www.cqbn.gov.cn/bmjz/bm/wsjkw/zwgk_88897/gkml/jczwgk/ylws/fwzn/jkfw/202112/W020211201409396304290.pdf., articleTitle=中国结核病预防控制工作技术规范, refAbstract=null), Reference(id=1241329770638660559, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[10], rfOrder=16, authorNames=National Health and Wellness Commission of the People's Republic of China, journalName=null, refType=null, unstructuredReference=National Health and Wellness Commission of the People's Republic of China. Technical specifications for tuberculosis prevention and control in China(2020 edition)[EB/OL] . [2025-05-10] . http://www.cqbn.gov.cn/bmjz/bm/wsjkw/zwgk_88897/gkml/jczwgk/ylws/fwzn/jkfw/202112/W020211201409396304290.pdf. (In Chinese), articleTitle=Technical specifications for tuberculosis prevention and control in China(2020 edition), refAbstract=null), Reference(id=1241329770751906775, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2023, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[11], rfOrder=17, authorNames=徐彩红, 赵雁林, journalName=中国结核病预防性治疗指南, refType=null, unstructuredReference=徐彩红， 赵雁林.中国结核病预防性治疗指南[M] .北京：人民卫生出版社，2023., articleTitle=null, refAbstract=null), Reference(id=1241329770915484641, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2023, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[11], rfOrder=18, authorNames=Xu CH, Zhao YL, journalName=Guidelines for preventive treatment of tuberculosis in China, refType=null, unstructuredReference=Xu CH, Zhao YL. Guidelines for preventive treatment of tuberculosis in China[M] . Beijing: People's Medical Publishing House, 2023.(In Chinese), articleTitle=null, refAbstract=null), Reference(id=1241329771058090988, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2022, volume=16, issue=1, pageStart=17, pageEnd=22, url=null, language=null, rfNumber=[12], rfOrder=19, authorNames=饶立歆, 蒋鸿琳, 陈静, journalName=首都公共卫生, refType=null, unstructuredReference=饶立歆，蒋鸿琳，陈静，等.我国结核病防治相关医务工作者结核分枝杆菌潜伏感染现况的Meta分析[J] .首都公共卫生，2022，16（1）：17-22., articleTitle=我国结核病防治相关医务工作者结核分枝杆菌潜伏感染现况的Meta分析, refAbstract=null), Reference(id=1241329771217474546, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2022, volume=16, issue=1, pageStart=17, pageEnd=22, url=null, language=null, rfNumber=[12], rfOrder=20, authorNames=Rao LX, Jiang HL, Chen J, journalName=Capital Journal of Public Health, refType=null, unstructuredReference=Rao LX, Jiang HL, Chen J, et al. Latent tuberculosis infection among TB-related health-care workers in China: a Meta-analysis[J] . Capital Journal of Public Health, 2022, 16(1): 17-22.(In Chinese), articleTitle=Latent tuberculosis infection among TB-related health-care workers in China: a Meta-analysis, refAbstract=null), Reference(id=1241329771360080886, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2021, volume=16, issue=8, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[13], rfOrder=21, authorNames=Nathavitharana RR, van der Westhuizen A, van der Westhuizen HM, journalName=PLOS One, refType=null, unstructuredReference=Nathavitharana RR, van der Westhuizen A, van der Westhuizen HM, et al. "If I've got latent TB, I would like to get rid of it": Derivation of the CARD (Constraints, Actions,Risks, and Desires) Framework informed by South African healthcare worker perspectives on latent tuberculosis treatment[J] . PLOS One, 2021, 16(8): e0254211., articleTitle="If I've got latent TB, I would like to get rid of it": Derivation of the CARD (Constraints, Actions,Risks, and Desires) Framework informed by South African healthcare worker perspectives on latent tuberculosis treatment, refAbstract=null), Reference(id=1241329771561407483, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2023, volume=23, issue=1, pageStart=914, pageEnd=null, url=null, language=null, rfNumber=[14], rfOrder=22, authorNames=H SNF, Manoharan A, Koh WM, journalName=BMC Health Services Research, refType=null, unstructuredReference=H SNF, Manoharan A, Koh WM, et al. Facilitators and barriers to latent tuberculosis infection treatment among primary healthcare workers in Malaysia: a qualitative study[J] . BMC Health Services Research, 2023, 23(1): 914., articleTitle=Facilitators and barriers to latent tuberculosis infection treatment among primary healthcare workers in Malaysia: a qualitative study, refAbstract=null), Reference(id=1241329771750150147, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2022, volume=12, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[15], rfOrder=23, authorNames=Wang F, Ren YL, Liu K, journalName=Frontiers in Cellular and Infection Microbiology, refType=null, unstructuredReference=Wang F, Ren YL, Liu K, et al. Large gap between attitude and action in tuberculosis preventive treatment among tuberculosis-related healthcare workers in eastern China[J] . Frontiers in Cellular and Infection Microbiology, 2022, 12: 991400., articleTitle=Large gap between attitude and action in tuberculosis preventive treatment among tuberculosis-related healthcare workers in eastern China, refAbstract=null), Reference(id=1241329771909533702, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2022, volume=19, issue=1, pageStart=60, pageEnd=null, url=null, language=null, rfNumber=[16], rfOrder=24, authorNames=Kawatsu L, Kaneko N, Imahashi M, journalName=AIDS Research and Therapy, refType=null, unstructuredReference=Kawatsu L, Kaneko N, Imahashi M, et al. Practices and attitudes towards tuberculosis and latent tuberculosis infection screening in People living with HIV/AIDS among HIV physicians in Japan[J] . AIDS Research and Therapy, 2022, 19(1): 60., articleTitle=Practices and attitudes towards tuberculosis and latent tuberculosis infection screening in People living with HIV/AIDS among HIV physicians in Japan, refAbstract=null), Reference(id=1241329772140220427, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2022, volume=55, issue=5, pageStart=428, pageEnd=435, url=null, language=null, rfNumber=[17], rfOrder=25, authorNames=Winardi W, Yudistira Nalapraya W, Sarifuddin S, journalName=Journal of Preventive Medicine and Public Health, refType=null, unstructuredReference=Winardi W, Yudistira Nalapraya W, Sarifuddin S, et al.Knowledge and attitudes of indonesian general practitioners towards the isoniazid preventive therapy program in Indonesia[J] . Journal of Preventive Medicine and Public Health, 2022, 55(5): 428-435., articleTitle=Knowledge and attitudes of indonesian general practitioners towards the isoniazid preventive therapy program in Indonesia, refAbstract=null), Reference(id=1241329774644219921, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, doi=null, pmid=null, pmcid=null, year=2019, volume=19, issue=1, pageStart=951, pageEnd=null, url=null, language=null, rfNumber=[18], rfOrder=26, authorNames=Ngo CQ, Manabe T, Vu GV, journalName=BMC Infectious Diseases, refType=null, unstructuredReference=Ngo CQ, Manabe T, Vu GV, et al. Difficulties in tuberculosis infection control in a general hospital of Vietnam: A knowledge, attitude, and practice survey and screening for latent tuberculosis infection among health professionals[J] . BMC Infectious Diseases, 2019, 19(1): 951., articleTitle=Difficulties in tuberculosis infection control in a general hospital of Vietnam: A knowledge, attitude, and practice survey and screening for latent tuberculosis infection among health professionals, refAbstract=null)], funds=[Fund(id=1241329766419190606, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, awardId=2023D01C57, language=CN, fundingSource=新疆维吾尔自治区自然科学基金项目(2023D01C57), fundOrder=null, country=null), Fund(id=1241329766498882385, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, awardId=TSYC202301B166, language=CN, fundingSource=“天山英才”医药卫生高层次人才培养计划(TSYC202301B166), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1241329761398608313, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, xref=1., ext=[AuthorCompanyExt(id=1241329761402802619, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, companyId=1241329761398608313, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=School of Public Health, Xinjiang Medical University, Urumqi, Xinjiang 830017, China), AuthorCompanyExt(id=1241329761415385532, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, companyId=1241329761398608313, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=1.新疆医科大学公共卫生学院，新疆 乌鲁木齐 830017)]), AuthorCompany(id=1241329761549603270, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, xref=2., ext=[AuthorCompanyExt(id=1241329761599934924, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, companyId=1241329761549603270, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=2.新疆维吾尔自治区疾病预防控制中心，新疆 乌鲁木齐 830002)])], figs=[ArticleFig(id=1241329765630661395, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, language=EN, label=Table 1, caption=

Knowledge of latent tuberculosis infection and preventive treatment of medical staff

, figureFileSmall=null, figureFileBig=null, tableContent=
知识点总例数例数比例（%）
您是否知晓结核潜伏感染？235
是21892.77
否/不清楚177.23
您觉得感染结核分枝杆菌后发病的几率有多大?235
5%～10%14963.40
20%～30%4619.57
50%3113.19
100%93.83
您知道结核潜伏感染筛查的方法包括哪些（多选题）？235
结核菌素皮肤试验23399.15
γ-干扰素释放试验20788.09
重组结核杆菌融合蛋白19582.98
其他5422.98
您知道结核潜伏感染高危人群包括哪些人群（多选题）？235
肺结核密切接触者235100.00
65岁以上老年人21089.36
HIV/AIDS患者22595.74
儿童和学生20888.51
尘肺病患者和免疫疾病患者10444.26
医务人员14461.28
糖尿病患者22093.62
您知道预防性治疗对象包括哪些人群（多选题）？235
与病原学阳性肺结核患者密切接触的5岁以下儿童22495.32
HIV感染者/AIDS患者22997.45
活动性肺结核患者密切接触者17875.74
其他免疫功能缺陷的高危人群17875.74
其他重点人群，如医务人员、羁押人员、无家可归者等
您觉得预防性治疗的效果如何？235
保证一直不发病125.11
降低发病概率14360.85
不清楚8034.04
您认为是否有必要对潜伏感染者开展预防性治疗？218
是15671.56
否2712.39
不清楚3516.06
), ArticleFig(id=1241329765760684830, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, language=CN, label=表1, caption=

结核病防治人员LTBI及预防性治疗知识知晓情况

, figureFileSmall=null, figureFileBig=null, tableContent=
知识点总例数例数比例（%）
您是否知晓结核潜伏感染？235
是21892.77
否/不清楚177.23
您觉得感染结核分枝杆菌后发病的几率有多大?235
5%～10%14963.40
20%～30%4619.57
50%3113.19
100%93.83
您知道结核潜伏感染筛查的方法包括哪些（多选题）？235
结核菌素皮肤试验23399.15
γ-干扰素释放试验20788.09
重组结核杆菌融合蛋白19582.98
其他5422.98
您知道结核潜伏感染高危人群包括哪些人群（多选题）？235
肺结核密切接触者235100.00
65岁以上老年人21089.36
HIV/AIDS患者22595.74
儿童和学生20888.51
尘肺病患者和免疫疾病患者10444.26
医务人员14461.28
糖尿病患者22093.62
您知道预防性治疗对象包括哪些人群（多选题）？235
与病原学阳性肺结核患者密切接触的5岁以下儿童22495.32
HIV感染者/AIDS患者22997.45
活动性肺结核患者密切接触者17875.74
其他免疫功能缺陷的高危人群17875.74
其他重点人群，如医务人员、羁押人员、无家可归者等
您觉得预防性治疗的效果如何？235
保证一直不发病125.11
降低发病概率14360.85
不清楚8034.04
您认为是否有必要对潜伏感染者开展预防性治疗？218
是15671.56
否2712.39
不清楚3516.06
), ArticleFig(id=1241329765903291177, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, language=EN, label=Table 2, caption=

Analysis of attitudes of medical staff towards the preventive treatment of latent tuberculosis infection

, figureFileSmall=null, figureFileBig=null, tableContent=
特征推荐预防性治疗（n=141）不推荐预防性治疗（n=77）χ2值P值
人数比例（%）人数比例（%）
性别4.5650.033
男2618.442431.17
女11581.565368.83
学历0.812α0.690
大专及以下5539.012633.77
本科8258.164862.34
硕士及以上42.8433.90
职业类别10.8390.004
医生2819.863140.26
护士3524.821215.58
管理人员7855.323444.16
从事结核病防治工作时间（年）1.2040.752
<35236.882633.77
3～63021.281519.48
6～9128.511012.99
≥9年4733.332633.77
知晓预防性治疗效果16.49<0.001
是10070.923342.86
否4129.084457.14
LTBI者开展预防性治疗必要性122.919<0.001
是13696.452025.97
否02735.06
不清楚53.553038.96
是否参加过LTBI相关培训5.2000.023
是10272.344457.14
否3927.663342.86
), ArticleFig(id=1241329766012343089, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, language=CN, label=表2, caption=

结核病防治人员LTBI预防性治疗态度分析

, figureFileSmall=null, figureFileBig=null, tableContent=
特征推荐预防性治疗（n=141）不推荐预防性治疗（n=77）χ2值P值
人数比例（%）人数比例（%）
性别4.5650.033
男2618.442431.17
女11581.565368.83
学历0.812α0.690
大专及以下5539.012633.77
本科8258.164862.34
硕士及以上42.8433.90
职业类别10.8390.004
医生2819.863140.26
护士3524.821215.58
管理人员7855.323444.16
从事结核病防治工作时间（年）1.2040.752
<35236.882633.77
3～63021.281519.48
6～9128.511012.99
≥9年4733.332633.77
知晓预防性治疗效果16.49<0.001
是10070.923342.86
否4129.084457.14
LTBI者开展预防性治疗必要性122.919<0.001
是13696.452025.97
否02735.06
不清楚53.553038.96
是否参加过LTBI相关培训5.2000.023
是10272.344457.14
否3927.663342.86
), ArticleFig(id=1241329766108812089, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, language=EN, label=Table 3, caption=

Concerns of health care workers regarding the preventive treatment of latent tuberculosis infection

, figureFileSmall=null, figureFileBig=null, tableContent=
问题合计（n=218）推荐者（n=141）不推荐者（n=77）
人次数比例（%）人次数比例（%）人次数比例（%）
担心预防性治疗者依从性差，难以管理7433.94139.226179.22
担心预防性治疗会产生不良反应9342.662215.607192.21
担心LTBI相关宣传较少，群众知识缺乏8438.531510.646989.61
担心预防性治疗保护效果不明确12758.266546.106280.52
担心工作难度大，LTBI者不配合，难以开展8438.533625.534862.34
), ArticleFig(id=1241329766188503871, tenantId=1146029695717560320, journalId=1227665162245664772, articleId=1241329581752373615, language=CN, label=表3, caption=

结核病防治人员对LTBI预防性治疗担心的问题

, figureFileSmall=null, figureFileBig=null, tableContent=
问题合计（n=218）推荐者（n=141）不推荐者（n=77）
人次数比例（%）人次数比例（%）人次数比例（%）
担心预防性治疗者依从性差，难以管理7433.94139.226179.22
担心预防性治疗会产生不良反应9342.662215.607192.21
担心LTBI相关宣传较少，群众知识缺乏8438.531510.646989.61
担心预防性治疗保护效果不明确12758.266546.106280.52
担心工作难度大，LTBI者不配合，难以开展8438.533625.534862.34
)], attaches=null, journal=Journal(id=1227664546253402114, delFlag=0, nameCn=现代预防医学, nameEn=Modern Preventive Medicine, nameHistory1=null, nameHistory2=null, issn=1003-8507, eissn=null, cn=51-1365/R, coden=null, periodic=3, language=CN, oaType=null, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=IeiuPXEZi6AA+k0VfvoiOQ==, journalPrice=null, startedYear=null, abbrevIsoEn=Modern Preventive Medicine, journalRemark=null, publicationField=null, createdTime=1770627636734, updatedTime=1770628902248, createdBy=18614031015, updatedBy=13701087609, firstLetterCn=M, firstLetterEn=M, subjectCode=Life Sciences, subjectName=null, subjectCodeEn=Life Sciences, subjectNameEn=null, picCn=IeiuPXEZi6AA+k0VfvoiOQ==, picEn=/9iTl8/ndms4tBz1fL28Pg==, jcr=null, cjcr=null, exts=[JournalExt(id=1227669854342280188, language=CN, name=现代预防医学, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1770628902278, updatedTime=1770628902278, createdBy=13701087609, updatedBy=13701087609, submissionGuidelinesUrl=, submissionAuthorUrl=http://xdyfyxzz.paperopen.com/#/regist, submissionEditorUrl=http://xdyfyxzz.paperopen.com/#/Login, submissionReviewUrl=http://xdyfyxzz.paperopen.com/#/Login, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""}), JournalExt(id=1227669854396806141, language=EN, name=Modern Preventive Medicine, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1770628902291, updatedTime=1770628902291, createdBy=13701087609, updatedBy=13701087609, submissionGuidelinesUrl=, submissionAuthorUrl=http://xdyfyxzz.paperopen.com/#/regist, submissionEditorUrl=http://xdyfyxzz.paperopen.com/#/Login, submissionReviewUrl=http://xdyfyxzz.paperopen.com/#/Login, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""})], databaseList=null, tenantJournalId=1227665162245664772, websiteList=[Website(id=1227687234141352800, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1227665162245664772, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/xdyfyx/CN, language=CN, createTime=1770633045945, createBy=18614031015, updateTime=1770633090526, updateBy=18614031015, name=现代预防医学-中文, tplId=1146099689490845704, title=现代预防医学, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1227687735088051072, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1227687234141352800, code=articleTextType, value=kx, createTime=1770633165380, updateTime=1770633165380, creator=18614031015, updator=18614031015), WebsiteProps(id=1227687735071273853, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1227687234141352800, code=banner, value=null, createTime=1770633165376, updateTime=1770633165376, creator=18614031015, updator=18614031015), WebsiteProps(id=1227687735113216899, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1227687234141352800, code=grayFlag, value=0, createTime=1770633165386, updateTime=1770633165386, creator=18614031015, updator=18614031015), WebsiteProps(id=1227687735062885244, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1227687234141352800, code=logo, value=https://castjournals.cast.org.cn/joweb/xdyfyx/CN/file/pic?fileId=/XB5plC0xuykmQnycvtyrw==, createTime=1770633165374, updateTime=1770633165374, creator=18614031015, updator=18614031015), WebsiteProps(id=1227687735125799813, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1227687234141352800, code=minRunFlag, value=0, createTime=1770633165389, updateTime=1770633165389, creator=18614031015, updator=18614031015), WebsiteProps(id=1227687735083856767, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1227687234141352800, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/xdyfyx/CN/file/pic, createTime=1770633165379, updateTime=1770633165379, creator=18614031015, updator=18614031015), WebsiteProps(id=1227687735121605508, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1227687234141352800, code=silenceFlag, value=0, createTime=1770633165388, updateTime=1770633165388, creator=18614031015, updator=18614031015), WebsiteProps(id=1227687735079662462, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1227687234141352800, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1770633165378, updateTime=1770633165378, creator=18614031015, updator=18614031015), WebsiteProps(id=1227687735096439681, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1227687234141352800, code=themeColor, value=null, createTime=1770633165382, updateTime=1770633165382, creator=18614031015, updator=18614031015), WebsiteProps(id=1227687735104828290, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1227687234141352800, code=themeStyle, value=null, createTime=1770633165384, updateTime=1770633165384, creator=18614031015, updator=18614031015)]), Website(id=1227687234338485094, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1227665162245664772, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/xdyfyx/EN, language=EN, createTime=1770633045992, createBy=18614031015, updateTime=1770633115374, updateBy=18614031015, name=现代预防医学-英文, tplId=1146101810881728533, title=Modern Preventive Medicine, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1227687709129507332, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1227687234338485094, code=articleTextType, value=kx, createTime=1770633159191, updateTime=1770633159191, creator=18614031015, updator=18614031015), WebsiteProps(id=1227687709108535809, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1227687234338485094, code=banner, value=null, createTime=1770633159186, updateTime=1770633159186, creator=18614031015, updator=18614031015), WebsiteProps(id=1227687709167256071, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1227687234338485094, code=grayFlag, value=0, createTime=1770633159200, updateTime=1770633159200, creator=18614031015, updator=18614031015), WebsiteProps(id=1227687709095952896, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1227687234338485094, code=logo, value=https://castjournals.cast.org.cn/joweb/xdyfyx/EN/file/pic?fileId=/XB5plC0xuykmQnycvtyrw==, createTime=1770633159183, updateTime=1770633159183, creator=18614031015, updator=18614031015), WebsiteProps(id=1227687709179838985, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1227687234338485094, code=minRunFlag, value=0, createTime=1770633159203, updateTime=1770633159203, creator=18614031015, updator=18614031015), WebsiteProps(id=1227687709121118723, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1227687234338485094, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/xdyfyx/EN/file/pic, createTime=1770633159189, updateTime=1770633159189, creator=18614031015, updator=18614031015), WebsiteProps(id=1227687709171450376, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1227687234338485094, code=silenceFlag, value=0, createTime=1770633159201, updateTime=1770633159201, creator=18614031015, updator=18614031015), WebsiteProps(id=1227687709112730114, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1227687234338485094, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1770633159187, updateTime=1770633159187, creator=18614031015, updator=18614031015), WebsiteProps(id=1227687709133701637, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1227687234338485094, code=themeColor, value=null, createTime=1770633159192, updateTime=1770633159192, creator=18614031015, updator=18614031015), WebsiteProps(id=1227687709154673158, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1227687234338485094, code=themeStyle, value=null, createTime=1770633159197, updateTime=1770633159197, creator=18614031015, updator=18614031015)])], journalTitle=现代预防医学, weixinUrl=null, journalUrl=http://xdyfyxzz.paperopen.com/, iacademicId=null, status=1, seqNo=null, journalTitleEn=Modern Preventive Medicine, journalPhotoCn=IeiuPXEZi6AA+k0VfvoiOQ==, journalPhotoEn=/9iTl8/ndms4tBz1fL28Pg==, journalFirstLetter=M, journalRecommend=null, journalNew=null, journalCollection=null, jcrJf=null, cjcrJf=null, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false), detailUrlCn=https://castjournals.cast.org.cn/joweb/xdyfyx/CN/10.20043/j.cnki.MPM.202501374, detailUrlEn=https://castjournals.cast.org.cn/joweb/xdyfyx/EN/10.20043/j.cnki.MPM.202501374, pdfUrlCn=https://castjournals.cast.org.cn/joweb/xdyfyx/CN/PDF/10.20043/j.cnki.MPM.202501374, pdfUrlEn=https://castjournals.cast.org.cn/joweb/xdyfyx/EN/PDF/10.20043/j.cnki.MPM.202501374, aliStartDate=null, aliEndDate=null, collectionFlag=false, citedCount=null, citedUrl=null, reference=null)
收藏切换
新疆结核病防治人员对结核潜伏感染及结核病预防性治疗的认知态度分析
收藏切换
PDF下载
克地尔叶克孜·吾甫尔 1 , 王森路 1, 2 , 黄涛 1 , 刘年强 2 , 加依那提·金格斯 1 , 古丽娜·巴德尔汗 2 , 王新旗 1, 2
现代预防医学 | 疾病预防控制 2025,52(13): 2466-2470
收起
收藏切换
现代预防医学 | 疾病预防控制 2025, 52(13): 2466-2470
新疆结核病防治人员对结核潜伏感染及结核病预防性治疗的认知态度分析
全屏
克地尔叶克孜·吾甫尔1, 王森路1, 2, 黄涛1, 刘年强2, 加依那提·金格斯1, 古丽娜·巴德尔汗2, 王新旗1, 2
作者信息
  • 1.新疆医科大学公共卫生学院，新疆 乌鲁木齐 830017
  • 2.新疆维吾尔自治区疾病预防控制中心，新疆 乌鲁木齐 830002

    • 克地尔叶克孜·吾甫尔（1999—），女，硕士在读，研究方向：公共卫生专业;

    王森路（1987—），男，博士在读，研究方向：结核病防治；

通讯作者:

王新旗，E-mail:
Knowledge and attitudes toward latent tuberculosis infection and preventive treatment among tuberculosis control workers in Xinjiang
WUFUER Ke-di-er-ye-zi-ke-zi1, Sen-lu WANG1, 2, Tao HUANG1, Nian-qiang LIU2, JINYISI Jia-yi-na-ti1, BADEERHAN Gu-li-na2, Xin-qi WANG1, 2
Affiliations
  • School of Public Health, Xinjiang Medical University, Urumqi, Xinjiang 830017, China
出版时间: 2025-07-10 doi: 10.20043/j.cnki.MPM.202501374
文章导航
收藏切换
摘要
收起
目的

探讨新疆维吾尔自治区（简称新疆）结核病防治人员对结核潜伏感染（latent tuberculosis infection, LTBI）者进行结核病预防性治疗的认知态度，旨在为促进结核病预防性治疗工作的推进提供科学依据。

方法

对新疆14个地州疾控机构和结核病定点医疗机构结核病防治人员进行调查。采用EpiData 3.1软件进行问卷数据录入，使用SPSS 26.0软件对收集的数据进行统计分析，以P<0.05为差异有统计学意义。

结果

92.77%（218/235）的防治人员知晓LTBI，63.40%（149/235）知晓LTBI发病概率，73.62%（173/235）对LTBI筛查方法知晓，29.79%（70/235）对LTBI高危人群知晓，65.11%（153/235）的防治人员对LTBI预防性治疗目标人群知晓，60.85%（143/235）清楚预防性治疗的效果。在知晓LTBI的防治人员中，71.56%（156/218）的防治人员认为有必要对LTBI者开展预防性治疗。不同性别（χ2=4.565，P=0.033）、不同职业类别（χ2=10.839，P=0.004）、是否知晓预防性治疗效果（χ2=16.490，P<0.001）、是否认为有必要对LTBI者开展预防性治疗（χ2=122.919，P<0.001）、是否参加过LTBI相关培训（χ2=5.200，P=0.023）在是否对LTBI者推荐预防性治疗之间比较，差异有统计学意义。“担心预防性治疗效果不明确”“担心预防性治疗会产生不良反应”“担心LTBI相关宣传较少，群众知识缺乏”“担心工作难度大，LTBI者不配合，难以开展”是医务人员对LTBI者开展预防性治疗主要担忧的问题。

结论

结核病防治人员对LTBI相关知识知晓情况以及对预防性治疗接受意愿均不高，应开展有针对性的培训和宣传教育活动，提高其对预防性治疗的接受度，以推动重点人群结核病预防性治疗工作的开展。

结核潜伏感染  /  预防性治疗  /  结核病防治人员  /  认知态度
Objective

To investigate the knowledge and attitudes of tuberculosis (TB) control workers regarding preventive treatment for latent tuberculosis infection (LTBI) in Xinjiang Uygur Autonomous Region, providing evidence for promoting LTBI preventive treatment.

Methods

A cross-sectional survey was conducted among TB control workers from 14 prefectures in Xinjiang. Data were entered using EpiData 3.1 and analyzed with SPSS 26.0, with statistical significance set at P<0.05.

Results

Among 235 respondents,92.77% (218/235) knew about LTBI, 63.40% (149/235) understood the probability of LTBI progression, 73.62% (173/235) knew screening methods, 29.79% (70/235) recognized high-risk populations, 65.11% (153/235) knew target groups for preventive treatment, and 60.85% (143/235) understood treatment efficacy. Of those aware of LTBI, 71.56% (156/218) believed preventive treatment was necessary. Significant differences (P<0.05) were found in recommending preventive treatment by gender (χ2=4.565, P=0.033), occupation (χ2=10.839, P=0.004), knowledge of treatment efficacy (χ2=16.490, P<0.001), perceived necessity (χ2=122.919, P<0.001), and training experience (χ2=5.200, P=0.023). Main concerns included uncertain efficacy (39.57%), adverse reactions (32.34%), public knowledge gaps (15.32%), and implementation difficulties (12.77%).

Conclusion

TB control workers demonstrated limited knowledge and moderate acceptance of LTBI preventive treatment. Targeted training and education programs are needed to improve acceptance and implementation of preventive treatment among high-risk populations.

Latent tuberculosis infection  /  Preventive treatment  /  Tuberculosis control workers  /  Knowledge and attitudes
克地尔叶克孜·吾甫尔, 王森路, 黄涛, 刘年强, 加依那提·金格斯, 古丽娜·巴德尔汗, 王新旗. 新疆结核病防治人员对结核潜伏感染及结核病预防性治疗的认知态度分析. 现代预防医学, 2025 , 52 (13) : 2466 -2470 . DOI: 10.20043/j.cnki.MPM.202501374
WUFUER Ke-di-er-ye-zi-ke-zi, Sen-lu WANG, Tao HUANG, Nian-qiang LIU, JINYISI Jia-yi-na-ti, BADEERHAN Gu-li-na, Xin-qi WANG. Knowledge and attitudes toward latent tuberculosis infection and preventive treatment among tuberculosis control workers in Xinjiang[J]. Modern Preventive Medicine, 2025 , 52 (13) : 2466 -2470 . DOI: 10.20043/j.cnki.MPM.202501374
正文
收起
结核潜伏感染（latent tuberculosis infection, LTBI）是对结核分枝杆菌抗原刺激做出持续免疫应答反应的一种状态，但无任何临床病原学或影像学证据证明是活动性结核（active tuberculosis, ATB）。全球约有1/4的LTBI者，若未及时对LTBI者采取相应措施，在其一生中有5%~10%的可能进展为ATB[1]。世界卫生组织（World Health Organization, WHO）推荐对LTBI高危人群开展预防性治疗，并将其作为实现结核病消除目标的关键策略之一[2]。我国作为结核病高负担国家，也将预防性治疗纳入结核病防治的重要内容[3]。新疆维吾尔自治区（简称新疆）结核病发病率远高于全国平均水平[4]，施行结核病防治“新疆模式”以来，已取得显著成效，但依旧是新疆重大公共卫生问题之一[5]。结核病防治人员对预防性治疗的认知态度对实施LTBI预防性治疗至关重要[6]。本研究由新疆结核病防治人员对LTBI者开展结核病预防性治疗的认知态度进行调查，旨在为当地制定有效的预防性防治策略提供科学依据。
1　资料与方法
收起
1.1　研究对象
研究对象涵盖新疆14个地州96个县市结核病防治人员，采用分层随机抽样法，以县区为单位，每个县区抽取疾控机构、定点医疗机构结核病防治人员各1～3名作为调查对象。在知情同意的情况下开展问卷调查，共调查235名结核病防治人员，回收问卷235份，有效问卷235份，问卷有效率100.00%。其中疾病预防控制中心结核病防治专职人员141名，结核病定点医疗机构医务人员94名。对26名结核病防治人员进行访谈，进一步了解其对LTBI的知晓情况及对预防性治疗的认知和态度。
1.2　研究方法
根据研究目的，通过咨询专家并查阅相关文献[1,6-7]制定调查问卷，调查内容包括基本人口学特征（如年龄、性别、文化程度、相关工作从事时间等）、LTBI和结核病预防性治疗相关知识、对预防性治疗的态度及担忧的问题等。自行设计访谈提纲，对从事结核病防治人员进行面对面访谈，了解其对LTBI及预防性治疗认知情况，每名医务人员访谈时间约为20 min。
1.3　统计学处理
采用EpiData 3.1软件建立数据库，进行数据双录入，使用SPSS 26.0软件进行数据整理与分析。计数资料采用频数和构成比描述。以是否认为对LTBI者开展预防性治疗有必要作为因变量，单因素分析采用χ2检验，以P<0.05为差异有统计学意义。定性资料分析采用主题框架法，利用分类归纳总结的方法对观点、行为进行描述性分析[8]。
本研究已获得新疆维吾尔自治区疾病预防控制中心伦理审查委员会的批准（批准编号：2023-016）。问卷调查和定性访谈均得到了研究对象的知情同意，并已签署纸质版知情同意书。
2　结果
收起
2.1　调查对象基本情况
本研究共纳入结核病防治人员235名，其中男女性别比为1∶3.43，平均年龄为（38.94±9.32）岁。文化程度以本科及以上为主，占62.98%；研究对象包括疾控机构结核病防治人员和定点医疗机构结核门诊医务人员，分别占60.00%（141/235）和40.00%（94/235）。66.81%（157/235）的医务人员参加过LTBI相关培训，其中包括71.63%（101/141）的疾控机构结核病防治人员和59.57%（56/94）定点医疗机构结核门诊医务人员。
2.2　LTBI和预防性治疗知识知晓情况
92.77%（218/235）的结核病防治人员知晓LTBI，63.40%（149/235）知晓LTBI发病概率，73.62%（173/235）的防治人员知晓LTBI筛查方法是结核菌素皮肤试验、γ-干扰素释放试验、重组结核杆菌融合蛋白，29.79%（70/235）的防治人员知晓LTBI的高危人群，65.11%（153/235）的防治人员知晓LTBI者预防性治疗的目标人群，60.85%（143/235）清楚预防性治疗的效果。在知晓LTBI的防治人员中，71.56%（156/218）的防治人员认为有必要对LTBI者开展预防性治疗。见表1。
2.3　结核病防治人员对预防性治疗的态度及其影响因素
在知晓LTBI的218名防治人员中，64.68%（141/218）的防治人员推荐对LTBI者开展预防性治疗。女性（χ2=4.565，P=0.033）、知晓预防性治疗效果（χ2=16.490，P<0.001）、认为有必要对LTBI者开展预防性治疗（χ2=122.919，P<0.001）、参加过LTBI相关培训（χ2=5.200，P=0.023）的防治人员推荐开展预防性治疗的比例较男性、不知晓预防性治疗效果、认为没必要/不清楚是否有必要对LTBI者开展预防性治疗以及未参加过LTBI相关培训的防治人员高。不同职业类别的防治人员在是否推荐预防性治疗方面也存在显著差异（χ2=10.839，P=0.004）。见表2。
2.4　结核病防治人员对预防性治疗的担忧
218名知晓LTBI的防治人员对预防性治疗提出了不同程度的担忧，其中“担心预防性治疗会产生不良反应”“担心LTBI相关宣传较少，群众知识缺乏”“担心预防性治疗效果不明确”是不推荐对LTBI者开展预防性治疗主要担忧的问题，分别占92.21%、89.61%、80.52%。在推荐对LTBI者开展预防性治疗的防治人员中，“担心预防性治疗保护效果不明确”则是最为担忧的问题，占46.10%。见表3。
2.5　结核病防治人员对预防性治疗具体问题的访谈
在本次访谈中，22名（84.62%）防治人员表示赞成对LTBI者开展预防性治疗，赞成的原因主要可以概括为：当地为结核病高负担地区，开展预防性治疗可以有效降低结核病发病率，同时对学生群体开展预防性治疗更具有价值，无论是对社会、家庭还是个人都是有益的。对预防性治疗持反对的原因主要可概括为以下几点：一是没有相关政策支持，预防性治疗工作难以开展；二是无法确定治疗效果，不能保证治疗后能够100%不发病；三是担心预防性治疗后，LTBI者对结核分枝杆菌产生耐药，更不利于其治疗；四是担心预防性治疗可能会出现的不良反应，特别是对年龄较小、免疫缺陷LTBI者的健康影响。同时防治人员也对提高LTBI者预防性治疗接受度提出了建议，主要包括：加强宣传，提高LTBI者的认知水平；加强对相关防治人员培训，在防治人员中对LTBI预防性治疗态度形成统一认知；给予一定的激励政策，如为接受预防性治疗的人群提供营养早餐、交通补助或其他生活补助；对取药不方便的LTBI者实施线上管理，如电子药盒或视频面视下服药。关于在全疆范围内推广结核病预防性治疗政策的建议，主要包括以下几个方面：一是政策经费保障；二是技术支持；三是加强宣教；四是多部门协作。
3　讨论
收起
对LTBI者进行预防性治疗是降低LTBI者进展为ATB风险的重要措施，也是实现终止结核病流行这一目标的重要策略[9]。我国出台的《中国结核病防治工作技术指南》及《中国结核病预防性治疗指南（2023版）》中，明确要求对结核病发病高危人群包括肺结核患者密切接触者、艾滋病病毒感染者/艾滋病患者以及其他高风险人群开展预防性治疗工作[10-11]。从事相关结核病防治工作的结核病防治人员不仅是结核病防治措施的实施者，同时也是感染结核分枝杆菌高风险人群[12]。因此提高防治人员对LTBI的认知水平，一方面可以积极推进结核潜伏感染预防性治疗工作，另一方面也可以有效提高防治人员自身对预防性治疗的接受度[13]。
本研究发现，大部分结核病防治人员知晓LTBI，但对于LTBI高危人群、发病概率、预防性治疗目标人群以及预防性治疗保护效果的知晓程度相对较低，这与重庆市对结核病防治人员的调查结果相同[7]。知晓LTBI的防治人员中，仅64.68%的防治人员推荐对LTBI者开展预防性治疗，推荐占比相对较低。参加过LTBI相关培训、知晓预防性治疗效果的防治人员更有可能推荐开展预防性治疗。以往研究表明，对LTBI及其治疗益处了解不足是防治人员不推荐或不愿意接受预防性治疗的重要原因[14]。因此加强对防治人员开展结核潜伏感染及预防性治疗相关培训，将有效提高其对预防性治疗的推荐程度。在本研究中，担心预防性治疗会产生不良反应、担心LTBI相关宣传较少，群众知识缺乏、担心预防性治疗保护效果不明确是防治人员不推荐对LTBI者开展预防性治疗的主要担心问题。
在本次访谈过程中，大部分防治人员对开展预防性治疗持肯定态度，这与我国先前开展的研究结果一致[6]。少数对开展预防性治疗持反对态度的防治人员则认为，治疗过程中发生不良反应、耐药、不配合、影响身心健康、无法保证治疗效果、无政策支持等是阻碍预防性治疗开展关键因素，这同国内外研究结果相似[15-17]。结核病防治人员对推广预防性治疗也提出了相关建议，包括政策经费保障、技术支持、加强宣教、多部门协作等。推广预防性治疗涉及多个领域，也受到多种因素的影响，包括政府重视程度、医疗卫生机构人员配置、当地卫生资源、相关人群接受预防性治疗的意愿等[18]。
基金
收起
  • 新疆维吾尔自治区自然科学基金项目(2023D01C57)
  • “天山英才”医药卫生高层次人才培养计划(TSYC202301B166)
文献
收起
参考文献 引证文献
排序方式：
[1]
Bar-Meir M, Pariente G, Romem A, et al. Identifying factors affecting latent tuberculosis treatment acceptance among healthcare workers: a retrospective analysis in a tertiary care centre[J] . BMJ Open, 2021, 11(9): e047444.
[2]
郭同磊， 辛赫男， 高磊.《世界卫生组织结核病整合指南模块1:结核病预防性治疗》解读[J] .中国防痨杂志，2023，45（8）：723-727.
Guo TL, Xin HN, Gao L. Interpretation of WHO consolidated guidelines on tuberculosis: Module 1: prevention: tuberculosis preventive treatment[J] .Chinese Journal of Antituberculosis, 2023, 45(8): 723-727.(In Chinese)
[3]
周林， 初乃惠， 陆伟.高危人群结核分枝杆菌潜伏感染检测及预防性治疗专家共识[J] .中国防痨杂志，2021，43（9）：874-878.
Zhou L, Chu NH, Lu W. Expert consensus on detection and preventive treatment of latent infection of Mycobacterium tuberculosis in high-risk populations[J] . Chinese Journal of Antituberculosis, 2021, 43(9): 874-878.(In Chinese)
[4]
余海茹，闫晔鑫，杨娇，等.2004至2021年中国肺结核发病趋势及空间分布特征[J] .郑州大学学报:医学版，2024，59（2）：274-279.
Yu HR, Yan YX, Yang J, et al. Incidence trend and spatial distribution characteristic of pulmonary tuberculosis in China from 2004 to 2021[J] .Journal of Zhengzhou University(Medical Sciences), 2024, 59(2): 274-279.(In Chinese)
[5]
王森路，刘年强，王新旗，等.结核病防治“新疆模式”的发展及成效[J] .中国防痨杂志，2024，46（2）：141-144.
Wang SL, Liu NQ, Wang XQ, et al. Development and effectiveness of"Xinjiang Model" for tuberculosis prevention and control[J] . Chinese Journal of Antituberculosis, 2024, 46(2): 141-144.(In Chinese)
[6]
Fa LF, Xu CH, Cheng J, et al.Acceptability of tuberculosis preventive treatment strategies among healthcare workers using an online survey - China, 2021[J] . China CDC Wkly, 2022, 4(11): 211-215.
[7]
雷蓉蓉，刘英，张婷，等.重庆市结核病防治医务人员结核潜伏感染及预防性治疗的认知态度分析[J] .现代预防医学，2020，47（9）：1647-1650, 1669.
Lei RR, Liu Y, Zhang T, et al. Analysis of cognitive attitudes toward latent tuberculosis infection and prophylactic treatment among medical personnel for tuberculosis control in Chongqing[J] . Modern Preventive Medicine,2020, 47(9): 1647-1650, 1669.(In Chinese)
[8]
姚晶，李智红，张怀庆，等.上海市静安区肺结核患者家庭内儿童青少年密接结核感染筛查情况及医务人员态度调查[J] .中国初级卫生保健，2024，38（7）：63-66.
Yao J, Li ZH, Zhang HQ, et al. Screening of latent infection in close contacts of children and adolescents in families of pulmonary tuberculosis patients in Jing'an district and study on attitudes of medical staff[J] .Chinese Primary Health Care, 2024, 38(7): 63-66.(In Chinese)
[9]
World Health Organization. WHO consolidated guidelines on tuberculosis: Module 1: tuberculosis preventive treatment[R] .Geneva: World Health Organization, 2020.
[10]
中华人民共和国国家卫生健康委员会.中国结核病预防控制工作技术规范[EB/OL] .[2025-05-10] . http://www.cqbn.gov.cn/bmjz/bm/wsjkw/zwgk_88897/gkml/jczwgk/ylws/fwzn/jkfw/202112/W020211201409396304290.pdf.
National Health and Wellness Commission of the People's Republic of China. Technical specifications for tuberculosis prevention and control in China(2020 edition)[EB/OL] . [2025-05-10] . http://www.cqbn.gov.cn/bmjz/bm/wsjkw/zwgk_88897/gkml/jczwgk/ylws/fwzn/jkfw/202112/W020211201409396304290.pdf. (In Chinese)
[11]
徐彩红， 赵雁林.中国结核病预防性治疗指南[M] .北京：人民卫生出版社，2023.
Xu CH, Zhao YL. Guidelines for preventive treatment of tuberculosis in China[M] . Beijing: People's Medical Publishing House, 2023.(In Chinese)
[12]
饶立歆，蒋鸿琳，陈静，等.我国结核病防治相关医务工作者结核分枝杆菌潜伏感染现况的Meta分析[J] .首都公共卫生，2022，16（1）：17-22.
Rao LX, Jiang HL, Chen J, et al. Latent tuberculosis infection among TB-related health-care workers in China: a Meta-analysis[J] . Capital Journal of Public Health, 2022, 16(1): 17-22.(In Chinese)
[13]
Nathavitharana RR, van der Westhuizen A, van der Westhuizen HM, et al. "If I've got latent TB, I would like to get rid of it": Derivation of the CARD (Constraints, Actions,Risks, and Desires) Framework informed by South African healthcare worker perspectives on latent tuberculosis treatment[J] . PLOS One, 2021, 16(8): e0254211.
[14]
H SNF, Manoharan A, Koh WM, et al. Facilitators and barriers to latent tuberculosis infection treatment among primary healthcare workers in Malaysia: a qualitative study[J] . BMC Health Services Research, 2023, 23(1): 914.
[15]
Wang F, Ren YL, Liu K, et al. Large gap between attitude and action in tuberculosis preventive treatment among tuberculosis-related healthcare workers in eastern China[J] . Frontiers in Cellular and Infection Microbiology, 2022, 12: 991400.
[16]
Kawatsu L, Kaneko N, Imahashi M, et al. Practices and attitudes towards tuberculosis and latent tuberculosis infection screening in People living with HIV/AIDS among HIV physicians in Japan[J] . AIDS Research and Therapy, 2022, 19(1): 60.
[17]
Winardi W, Yudistira Nalapraya W, Sarifuddin S, et al.Knowledge and attitudes of indonesian general practitioners towards the isoniazid preventive therapy program in Indonesia[J] . Journal of Preventive Medicine and Public Health, 2022, 55(5): 428-435.
[18]
Ngo CQ, Manabe T, Vu GV, et al. Difficulties in tuberculosis infection control in a general hospital of Vietnam: A knowledge, attitude, and practice survey and screening for latent tuberculosis infection among health professionals[J] . BMC Infectious Diseases, 2019, 19(1): 951.
2025年第52卷第13期
PDF下载
58
22
引用本文
BibTeX
文章信息
doi: 10.20043/j.cnki.MPM.202501374
  • 接收时间：2025-01-22
  • 首发时间：2026-03-19
  • 出版时间：2025-07-10
补充材料
相关文章
文章信息
作者
出版历史
  • 收稿日期：2025-01-22
基金
新疆维吾尔自治区自然科学基金项目(2023D01C57)
“天山英才”医药卫生高层次人才培养计划(TSYC202301B166)
作者信息
    1.新疆医科大学公共卫生学院，新疆 乌鲁木齐 830017
    2.新疆维吾尔自治区疾病预防控制中心，新疆 乌鲁木齐 830002

通讯作者:

王新旗，E-mail:
参考文献
分享链接
https://castjournals.cast.org.cn/joweb/xdyfyx/CN/10.20043/j.cnki.MPM.202501374
分享至
全文二维码

扫描看全文

引用本文
BibTeX
本文的引用情况
2种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
相关链接
论文
最新文章
热读文章
热点专题
内参
蓝皮书
产业发展报告
传播力报告
期刊分级目录
资讯
学术新闻
行业新闻
学术会议
行业会议
关于
关于我们
联系我们
北京市海淀区学院南路86号
100081
010-62199257
qkjq@cast.org.cn

中国科学技术协会版权所有 京ICP 备10216604号-4 海淀分局备案 1101084647
科技导报社主办 中国科协信息中心技术支持