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Research progress and prospects of viral diseases in giant pandas
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Songrui LIU1, Yunli LI1, 2, Hongwen ZHANG1, Xiaoyan SU1, Dongsheng ZHANG1, Chanjuan YUE1, Jianhong ZENG1, Rong HOU1, *
Acta Microbiologica Sinica | 2025, 65(12) : 5257 - 5270
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Acta Microbiologica Sinica | 2025, 65(12): 5257-5270
• Review •
Research progress and prospects of viral diseases in giant pandas
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Songrui LIU1, Yunli LI1, 2, Hongwen ZHANG1, Xiaoyan SU1, Dongsheng ZHANG1, Chanjuan YUE1, Jianhong ZENG1, Rong HOU1, *
Affiliations
  • 1.The Conservation of Endangered Wildlife Key Laboratory of Sichuan Province, Chengdu Research Base of Giant Panda Breeding, Chengdu, Sichuan, China
  • 2.College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan, China
Published: 2025-12-04 doi: 10.13343/j.cnki.wsxb.20250454
Outline
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In recent years, the widespread application of new technologies such as viral metagenomics has expanded our understanding of viral diseases in giant pandas. In addition to the previously reported infections with canine distemper virus, rotavirus, and parvovirus, the viruses carried by giant pandas exhibit increasing diversity and unique genetic variation characteristics. The growing population size and density of giant pandas post serious challenges to the population biosecurity, especially the prevention and control of viral diseases. To better understand the epidemiological characteristics of viral diseases in giant pandas, as well as the current status of the prevention and control for the development of effective strategies, we review the studies about viral diseases in giant pandas. This paper systematically elucidates the infection characteristics and hazards of major viral pathogens, as well as diagnostic methods, treatment measures, and preventive strategies. Additionally, the paper explores the bottlenecks and challenges encountered in developing and applying vaccines for giant pandas and the difficulties faced in viral disease research and proposes future research directions and recommendations, aiming to provide a scientific basis for preventing and controlling viral diseases in giant pandas.

giant panda  /  canine distemper virus  /  parvovirus  /  rotavirus  /  novel virus
Songrui LIU, Yunli LI, Hongwen ZHANG, Xiaoyan SU, Dongsheng ZHANG, Chanjuan YUE, Jianhong ZENG, Rong HOU. Research progress and prospects of viral diseases in giant pandas[J]. Acta Microbiologica Sinica, 2025 , 65 (12) : 5257 -5270 . DOI: 10.13343/j.cnki.wsxb.20250454
Funding
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  • National Key Research and Development Program of China(2023YFF1305402)
  • Research Project of Chengdu Research Base of Giant Panda Breeding(2022CPB-Y01)
  • Research Project of Chengdu Research Base of Giant Panda Breeding(2024CPB-Y04)
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Year 2025 volume 65 Issue 12
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Article Info
doi: 10.13343/j.cnki.wsxb.20250454
  • Receive Date：2025-06-10
  • Online Date：2025-12-08
  • Published：2025-12-04
Article Data
Affiliations
History
  • Received：2025-06-10
  • Accepted：2025-06-27
Funding
National Key Research and Development Program of China(2023YFF1305402)
Research Project of Chengdu Research Base of Giant Panda Breeding(2022CPB-Y01)
Research Project of Chengdu Research Base of Giant Panda Breeding(2024CPB-Y04)
Affiliations
    1.The Conservation of Endangered Wildlife Key Laboratory of Sichuan Province, Chengdu Research Base of Giant Panda Breeding, Chengdu, Sichuan, China
    2.College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan, China

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Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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