Objective To investigate the pesticide residue of fruits and vegetables in Qingpu District of Shanghai, Valuate the risk assessment of pesticide residues in primary and middle school students in Qingpu district. Methods From 2021 to 2022, 252 fruits and vegetables from 7 towns in Qingpu District of Shanghai were collected, and 46 pesticide residues in fruits and vegetables were detected by LC/MS. The acute and chronic dietary exposure risks of primary and secondary school students in Qingpu District of Shanghai was assessed using the results of pesticide residue detection, combined with food consumption in the dietary nutrient intake survey of Qingpu students. Results 15 pesticides of all total 46 pesticides were detected, 12 pesticides exceeded the standard, the highest detection rate was tthiamethoxam (29.76%), the highest exceeding rate was clothianidin (27.78%). Among the 6 kinds of fruits and vegetables, the highest detection rate was strawberry (88.10%), and the highest o exceeding rate was solanaceae (76.19%). The dietary exposure results showed that the acute exposure risks (acute hazardquotient) of methamidophos and dichlorvos weir 562% and 452% respectively, the chronic exposure risk (chronic hazardquotient) of dichlorvos was 434%, and the dietary acute chronic exposure risks of other pesticides were less than 100%. Conclusion There are pesticide residues in fruits and vegetables in Qingpu District of Shanghai. The dietary exposure risk of methamphetamine and dichlorvos in fruits and vegetables is high, which should be paid attention to by the regulatory authorities. The dietary exposure risk of other pesticides is low, but the high detection rate and over-standard rate of fruits and vegetables should be paid attention to.

In this paper, the equipment management, personnel training and quality control of the laboratory are comprehensively assessed by adopting quality control methods such as checklist evaluation and traceability management. Taking a food testing laboratory as an example, it quantitatively analyzes its quality management and gives the evaluation and improvement suggestions on equipment management, personnel training and quality control of the laboratory. Meanwhile, in the process of establishing a traceable management system, the management of quality control should also be strengthened to improve the accuracy and reliability of testing. Through the improvement and refinement of the laboratory, it can not only enhance the overall quality level of the testing laboratory, but also contribute to the maintenance of social public safety and health.

Compared with most of the current published instruments and equipment management risk research literature, generally only pay attention to the risk identification of individual links, and there are problems such as incomplete risk identification and analysis, which will affect the effectiveness of instrument and equipment risk management. In order to guide the inspection body and laboratory to carry out the risk management of instruments and equipment more reasonably, risk identification is carried out from the aspects of the whole life cycle and safety of instruments and equipment, and the identified risks are analyzed and evaluated, and risk disposal suggestions are put forward according to the evaluation results. Encourage inspection body and laboratory to always meet the requirements of management system and compliance operation in terms of instrument and equipment risk management.

Objective: To achieve rapid on-site detection of benzoic acid and sorbic acid, two common preservatives in cosmetics, and improve detection efficiency and on-site detection capabilities. Methods: A portable Raman spectrometer which used silver nanoparticles as the enhancement substrate for surface enhanced Raman spectroscopy (SERS) was used to detect benzoic acid and potassium sorbate in cosmetics. Results: Benzoic acid and sorbic acid had characteristic Raman peaks at ${1157}{\mathrm{\;{cm}}}^{-1}$ and ${871}{\mathrm{\;{cm}}}^{-1}$,respectively. Further research showed that the concentrations of benzoic acid and sorbic acid were linearly correlated with the intensity of their characteristic Raman peaks, making quantitative detection possible. This was confirmed by traditional liquid chromatography, and the quantitative results were consistent. Conclusion: This SERS method has the advantages of simplicity, speed, and efficiency, and is expected to achieve rapid on-site detection of preservatives.

With the continuous development of China's manufacturing industry and the increase in international trade, the requirements for product quality and safety are constantly increasing. Enterprises need to establish a modern and comprehensive laboratory to provide strong technical support for themselves and ensure the quality and international competitiveness of their products. Taking the laboratory construction of auto parts manufacturing enterprises as an example, this paper studied the process and method of industrial product testing laboratory construction, summarized the general process and method of laboratory construction, Including needs assessment and project planning, site selection and space design, equipment procurement and installation, personnel recruitment and training, quality management system establishment, laboratory safety and environmental protection, laboratory information and digitization, continuous improvement and technological innovation, etc., and put forward relevant suggestions to provide theoretical reference for the construction of related laboratories.