Objective: This study aims to explore a method for determining the concentration of free amino acids in cell culture media based on ultra performance liquid chromatography (UPLC). Methods Researchers used UPLC technology combined with optimized sample processing Methods to efficiently and accurately determine free amino acids in cell culture medium. Results The research results indicate that the UPLC method can quickly and reliably determine the concentration of free amino acids in cell culture medium, providing an effective means for monitoring and optimizing cell culture in the biopharmaceutical industry. Conclusion Accurate determination of amino acid concentration not only helps to better understand the dynamic changes of key nutrients in cell culture media, but also provides important data support for process optimization in the production process.

Objective The aim of this study is to investigate the variation of SERS effect intensity with the distance between probe molecules and the enhanced surface using atomic layer deposition (ALD) technology. Methods The study used ALD technology to deposit two-dimensional materials with different thicknesses on the surface of SERS to block raman probe molecules from the surface, exploring the weakening effect of different interaction distances on the SERS effect of the surface, and studying the changes in raman spectral intensity of probe molecules;the study used a silver-silicon combination as the SERS substrate, and a crystal violet aqueous solution with a concentration of ${10}^{-4}\mathrm{\;{mol}}/\mathrm{L}$ as a raman probe to conduct SERS effect exploration experiments on two-dimensional materials with different thicknesses. Results The final experimental results prove that the liquid SERS spectral intensity at the ${532}\mathrm{\;{nm}}$ laser wavelength generally weakens with the increase in the thickness of the two-dimensional material. Conclusion 5 nm thickness is its limiting distance.

Objective The aim of this study is to investigate the variation of SERS effect intensity with the distance between probe molecules and the enhanced surface using atomic layer deposition (ALD) technology. Methods The study used ALD technology to deposit two-dimensional materials with different thicknesses on the surface of SERS to block raman probe molecules from the surface, exploring the weakening effect of different interaction distances on the SERS effect of the surface, and studying the changes in raman spectral intensity of probe molecules;the study used a silver-silicon combination as the SERS substrate, and a crystal violet aqueous solution with a concentration of ${10}^{-4}\mathrm{\;{mol}}/\mathrm{L}$ as a raman probe to conduct SERS effect exploration experiments on two-dimensional materials with different thicknesses. Results The final experimental results prove that the liquid SERS spectral intensity at the ${532}\mathrm{\;{nm}}$ laser wavelength generally weakens with the increase in the thickness of the two-dimensional material. Conclusion 5 nm thickness is its limiting distance.

The application of the 7S concept in the construction of metrology laboratories and their standardized management can significantly enhance organizational effectiveness, guarantee experimental accuracy, enhance safety awareness, and through continuous improvement to achieve lasting job satisfaction and performance optimization, which is a necessary condition for the realization of high-efficiency, high-quality laboratory operations. This paper is aimed at measuring laboratory construction and standardized management of the 7S concept of the integration of strategies to carry out research, aims to explore the construction of measuring laboratories, standardized management of how to achieve the development of management programs based on the $7\mathrm{\;S}$ concept through case studies. Only in this paper, for China’s measurement laboratory construction units to learn and reference.

In the process of college education,it is necessary to use various facilities and tools,so many colleges and universities build special laboratories to provide environment and conditions for experimental teaching. Especially in the context of the rapid development of science and technology, schools pay more and more attention to experimental education and improve the quality of laboratory water. They have not only invested a large amount of construction funds, but also formulated more perfect laboratory management plans to promote the continuous improvement of laboratory management. But in the actual management, many colleges and universities still have some problems.Because the scale of laboratory assets has expanded,the number of instruments and equipment has increased, and the value has increased, the management difficulty has also increased, and there are higher requirements for management model innovation. This paper takes university teaching laboratory as the research object, expounds several common teaching laboratory management modes, analyzes the management system and operation mode of China's teaching laboratory, and puts forward the practical strategy of university teaching laboratory management mode.

"Method" is one of the five elements of total quality management. In the inspection and testing laboratory, "method" refers to the method used in the whole process of testing. Laboratory information management system can combine scientific laboratory management theory and computer technology organically, and provide advanced technical support for the overall improvement of laboratory management level. This paper combined the "method" of the five elements of quality management with the laboratory information management system, conducted in-depth discussions from three aspects: Standard management, electronic original record management and quality system document management, and verified that the laboratory information management system could assist managers to discover and control the key factors affecting the inspection quality, so as to achieve quality improvement and self-perfection of the quality system. Improve the competitiveness of the laboratory.

With the continuous development of China's manufacturing industry and the increase in international trade, the requirements for product quality and safety are constantly increasing. Enterprises need to establish a modern and comprehensive laboratory to provide strong technical support for themselves and ensure the quality and international competitiveness of their products. Taking the laboratory construction of auto parts manufacturing enterprises as an example, this paper studied the process and method of industrial product testing laboratory construction, summarized the general process and method of laboratory construction, Including needs assessment and project planning, site selection and space design, equipment procurement and installation, personnel recruitment and training, quality management system establishment, laboratory safety and environmental protection, laboratory information and digitization, continuous improvement and technological innovation, etc., and put forward relevant suggestions to provide theoretical reference for the construction of related laboratories.

With the continuous development of China's manufacturing industry and the increase in international trade, the requirements for product quality and safety are constantly increasing. Enterprises need to establish a modern and comprehensive laboratory to provide strong technical support for themselves and ensure the quality and international competitiveness of their products. Taking the laboratory construction of auto parts manufacturing enterprises as an example, this paper studied the process and method of industrial product testing laboratory construction, summarized the general process and method of laboratory construction, Including needs assessment and project planning, site selection and space design, equipment procurement and installation, personnel recruitment and training, quality management system establishment, laboratory safety and environmental protection, laboratory information and digitization, continuous improvement and technological innovation, etc., and put forward relevant suggestions to provide theoretical reference for the construction of related laboratories.

As an advanced intelligent management tool, intelligent scheduling system plays an increasingly important role in laboratory management, which can help laboratory personnel manage laboratory resources more effectively, improve laboratory efficiency, availability and safety, and enhance the laboratory's marketable competitiveness. This paper mainly introducecd the application of the intelligent scheduling system in the laboratory and the problems encountered, put forward the corresponding solutions, and discussed the future development trend of the intelligent scheduling system, which providing a theoretical basis for the subsequent technical development.

Objective To build capability verification public service platform based on the proposed recommendation algorithm. Methods Using big data and artificial intelligence related technologies, after the preprocessing of the ability verification data over the years, the recommendation algorithm model of the supply and demand matching between the provider and the participant is established and trained. After the training meets the requirements, the recommendation accuracy of the algorithm is verified in the core business process of the ability verification. Further explore the needs of all parties in the field of capability verification, integrate the resources of all parties in the field of capability verification, and build a national public service platform for capability verification by using unified data specification, unified business process and unified business description method. Results By using this algorithm model, the supply and demand matching of the providers and participants in the capability verification service on the platform has a better fit than other platforms without using the algorithm. Conclusion The construction of the public service platform for capability verification based on recommendation algorithm