Latest ArticlesObjective Measurement uncertainty is a parameter closely related to the measurement results and is indispensable for the quality control of laboratory data. In this paper, we analyze the source of the uncertainty of sulfur dioxide emission concentration in the exhaust of fixed pollution sources, find out the various uncertainty components affecting the measurement results, and conduct the analysis and evaluation of the measurement uncertainty, so as to provide an important reference for the analysis and judgment of the accuracy of environmental monitoring data and calibrate the results. Methods The concentration of sulfur dioxide emission in fixed pollution waste gas is measured according to UV absorption method. Results The extended uncertainty of the resulting determination was 6.9%. Conclusion The uncertainty component introduced by the instrument system effect is relatively large. In addition to regular sending to the technical supervision department for verification, the user of the instrument should also carry out regular maintenance and necessary period verification to ensure the accuracy of the instrument and the repetition of the measurement.
This overview discusses in detail the key role of inspection and testing laboratories in technological innovation and quality management. Firstly, technological innovation is an essential tool for laboratories to enhance their testing capabilities and technical standards, and it is also the core driving force for their sustainable development. Secondly, quality management is the core aspect of ensuring the accuracy and reliability of testing reports issued by inspection and testing laboratories. Labs need to establish a scientific and standardized quality management system and continuously improve it. At the same time, the China National Accreditation Service for Conformity Assessment (CNAS), as a signatory of international mutual recognition agreements, has put forward explicit requirements for the management of personnel capabilities in inspection institutions. Furthermore, chemical metrology technology faces new development and challenges. This article will delve into these important topics.
Promethazine hydrochloride has good effects on skin, ear, nose, and throat, as well as internal medicine diseases. Therefore, it is widely used in clinical pediatrics. Due to its large size, the use of this drug in clinical pediatric medicine is limited to some extent. Excessive content of promethazine hydrochloride tablets can easily cause adverse reactions, so it is necessary to analyze the content of promethazine hydrochloride tablets in order to adjust the medication deviation. High performance liquid chromatography can combine pharmacokinetics to analyze the actual content of drugs. With its advantages of high sensitivity and specificity, it has been widely applied in drug analysis in recent years. High performance liquid chromatography is based on the application scope of drugs, forming a comprehensive chromatographic drug analysis plan, timely adjusting chromatographic phase changes, and conducting scientific evaluations to enhance separation efficiency and accurately determine drug content, in order to optimize the application of drug components in high-performance liquid chromatography analysis. This study mainly reviews the research on the determination of the content of promethazine hydrochloride tablets in children's medication by high-performance liquid chromatography, in order to provide reference for the rational use of drugs in pediatric clinical practice.
Objective To establish the method of microbial limit test of Fufang Huangliansu tablets. Methods According to the provisions of Part Four of the 2020 edition of the Pharmacopoeia of the People's Republic of China, the applicability test of microbial limit testing methods shall be gradually carried out using methods such as plate pouring method, increasing dilution ratio, and dilution combined with membrane filtration. Results The membrane filtration method was used for aerobic bacteria counting. The medium dilution method was used for counting total combined molds and yeasts. The direct inoculation method was used for three types of control bacteria that must be tested according to drug standards. Conclusion The microbiological limit test method for this drug proposed in this experiment is simple and easy to implement.
To avoid major differences in the testing process, help customers correctly understand and use reports, and effectively control risks, according to the relevant requirements of Laboratory Accreditation and Inspection Body and Laboratory Mandatory Approval, combined with practical experience, this paper puts forward 10 aspects that should be agreed in the inspection and testing entrustment agreement, analyzes more than 10 items that should be declared in the inspection and testing report, summarizes the key issues that should be paid attention to, and provides general requirements for the industry to refer to, which has a great practical guiding significance for the standardization of inspection and testing activities.
With the continuous improvement of medical informatization level, the application of Hospital Laboratory Information System (LIS) in the medical field is becoming increasingly widespread. As the core link of hospital laboratory information systems, data transmission's security, stability, and efficiency directly affect the quality and efficiency of medical services. This article first outlines the definition and functions of hospital laboratory information systems, as well as the current development status of LIS systems. Subsequently, an in-depth analysis was conducted on the technical requirements for data transmission in hospital laboratory information systems, including the characteristics of data transmission, security requirements, and optimization directions. Through this study, the aim is to provide useful reference and inspiration for the optimization and development of data transmission technology in hospital laboratory information systems.
Drug testing is a professional work, which contains many details, any link will affect the efficiency and quality of the overall work. High performance liquid chromatography (HPLC) has the characteristics of high sensitivity, short test time and wide application range. Its application in drug testing can improve the shortcomings of traditional testing techniques and make the test results more reliable and accurate. This paper first describes the concept of high performance liquid chromatography, then analyzes the characteristics of high performance liquid chromatography, including short detection time, high sensitivity and wide application range, and then analyzes the value of practicing high performance liquid chromatography in drug testing, including timely detection of drug processing problems, ensuring drug safety, and promoting the improvement of drug testing technology. Finally, the application of high performance liquid chromatography in drug testing was discussed.
Objective This paper aims to explore how to introduce the concept of risk management into the laboratory quality control and optimize the laboratory quality management strategy. Methods By analyzing the principle of laboratory quality control and the integration mechanism of risk management and quality control, the deficiencies in standardization of quality control procedures, risk prevention mechanism and data utilization feedback in Chinese laboratories are revealed. Results Based on this, optimization paths such as building standardized quality control procedures, multi-dimensional risk prevention system and data-driven monitoring feedback mechanism are proposed. Conclusion The research shows that integrating risk management into laboratory quality control can significantly improve the quality management level, reduce quality risks, and provide a strong quality guarantee for scientific research.
Objective Reasonably set up and implement the measurement and calibration scheme of the yoke magnetic particle flaw detector, including calibration demand analysis, calibration preparation, calibration implementation, calibration work after calibration, calibration summary and analysis, etc., to improve the lifting force, safety, permeability and sensitivity of the yoke magnetic particle flaw detector. Methods Taking the CDX-III magnetic yoke magnetic particle flaw detection machine as an example, the calibration implementation preparation, working environment simulation, power inspection, insulation resistance and strength test, current error test, current measuring device access, sensitivity detection and other specific schemes were reasonably designed. Experimental research method was adopted to analyze the rationality of the calibration scheme through experimental results. Results Through the use of this measurement calibration scheme, the lifting force, safety, permeability and sensitivity of the yoke magnetic particle flaw detection machine can be improved to meet the national metrology standards and requirements. Conclusion This measurement calibration scheme has systematic and fine characteristics, and pays attention to the use of environmental simulation, enhance its practicality and rationality, more comprehensive and accurate, worthy of promotion and use.
Inter-cresol is a common environmental pollutant and industrial raw material, and its sensitive, accurate and rapid detection is crucial for environmental monitoring and food safety. Molecularly imprinted polymers (Molecularly Imprinted Polymers, MIPs) have shown an attractive application prospect in improving the detection method due to their unique molecular recognition ability. This paper systematically discusses the application of MIPs technology in improving detection sensitivity, simplifying sample processing and enhancing selective identification, and puts forward a series of innovative imprinting strategies and detection schemes, in order to provide new ideas and methods for solving the current technical bottleneck in parcresol detection.