This paper discusses the significance of the construction of open sharing platform for large instruments and equipment, and analyzes the main problems existing in the construction of large instrument sharing platform in local undergraduate colleges, such as insufficient investment funds, imperfect sharing mechanism, weak testing level and insufficient utilization of instruments and equipment. The paper puts forward some practical suggestions on the construction of the open sharing platform of large instruments and equipment by increasing the capital investment, improving the open sharing mechanism, assembling and strengthening the experimental technical team, and developing and mining the testing

Quality control of cement concrete raw materials in highway engineering is a key factor in ensuring engineering quality and durability. This paper analyzes the importance, content and existing problems of cement concrete raw material testing and inspection, and proposes a series of quality control measures. These measures include formulating scientific and reasonable testing and inspection processes, strengthening the management of raw material use and inspection, and optimizing the inspection environment. By taking these measures, the quality of cement concrete engineering can be effectively improved, and the smooth construction and long-term use of highway engineering can be guaranteed.

Total nitrogen, as a fundamental indicator for water quality monitoring, is an important indicator for measuring the degree of water pollution, self purification status, and eutrophication. It is of great significance for evaluating water quality and protecting the ecological environment. This article explores the main factors affecting the detection process of total nitrogen in water using ultraviolet digestion spectrophotometry. By optimizing the detection process through methods such as sample self influencing factors, digestion process control, and reagent and drug purification, the problem of high experimental blank has been effectively solved, and the reliability and accuracy of the detection have been improved.

Total sulfur in coal is one of the important indicators for evaluating coal quality. In order to effectively and economically utilize coal resources, it is necessary to comprehensively understand the total sulfur content in coal. Based on the principle of coulometric titration and the consideration of man-machine material loop measurement, this paper deeply explores the main factors affecting the measurement accuracy, aiming to significantly improve the accuracy of total sulfur determination through systematic analysis of the influence of various factors on the detection and standardization of the correct use, inspection and maintenance of the instrument.

Objective To study the automatic iodine analyzer to detectthe content of iodine in urine, so as to provide a scientific andefficient method for the majority of urinary iodine detection workers. Methods The linear range and correlation coefficient, detection limit,precision and accuracy of the method were tested to understand thefeasibility of the method. Results The linear range of this method is $0 \sim {400}\mathrm{{\mug}}/\mathrm{L}$ , the linear equation was $\lg A =- {0.0014C}+ {0.0013}$ , thecorrelation coefficient(r)was 0.9998, and the Limit of Detection (LD)was ${3.9\mu }\mathrm{g}/\mathrm{L}$ ,the relative standard deviation (RSD) was ${2.7}\%\sim {4.3}\%$ ; the detectionresults of low and high concentrations of urinary iodine referencematerials were in the range of uncertainty; 50 urine samples of pregnantwomen were randomly selected for iodine determination. By comparing theautomatic iodine analyzer with the manual method, the relative deviationof the results is $-{9.9}\%\sim {12.8}\%$ , which meets thequality control requirements of the National Reference Laboratory foriodine deficiency disorders for 3 consecutive years, he participated inthe national external quality control examination of IDD laboratoriesand passed all of them. Conclusion The linear range, correlationcoefficient, detection limit, precision and accuracy of the method aresatisfactory, and the method has a high degree of automation, reducingthe detection time and the workload of the staff, at the same time, ithas advantages in toxicity and waste disposal, so the automatic iodineanalyzer method is suitable for the determination of iodine in urine,especially for the detection of large-scale urine iodine, suitable forpopularization.

Objective To establish a high performance liquidchromatography method for the determination of the content uniformity ofpromethazine hydrochloride, and to provide a reliable experimental basisfor the subsequent study of the content uniformity and content qualityof pediatric drugs after manual breaking tablets. Methods Highperformance liquid chromatography was used, octadecyl silane bondedsilica gel was used as the column filling agent, water (adjusted pH to2.3 with glacial acetic acid)-methanol (55 : 45) was used as the mobilephase, and the detection wavelength was ${254}\mathrm{\;{nm}}$ . ResultsPromethazine hydrochloride showed a good linear relationship in therange of 17.392~26.088 μg/mL, and the linear equation was: $\mathrm{Y}= {55272}\mathrm{X}+{348938}\left({{r}^{2}= {0.9986}}\right)$ . The method recoveryrate was between 100.22% and 101.40%, and the RSD was ${0.49}\%$ . The content uniformity ofpromethazine hydrochloride was in accordance with the provisions of thefour general principles of the Chinese Pharmacopoeia 2020 edition.Finally, this method was used to analyze the accuracy of children’sdrugs by different methods of dosing by the content and contentuniformity of promethazine hydrochloride tablets. Conclusion The method has strong specificity in determining the content uniformity and content of promethazine hydrochloride, and the accuracy and precision are good. The dose accuracy of children’s tablets is reduced by many times of dosing, and it also provides very important data theoretical and practical significance for promoting the dose accuracy of children’s tablets.

Objective To analyze the content of heavy metals in water and fish in Huayuan River. Methods Microwave digestion and inductively coupled plasma mass spectrometry (ICP-MS) were used to determine the heavy metal content of common freshwater fish such as Branchfish, Carassius elegans, Siniperca elegans and grass carp in Huayuan River. Results The content of heavy metals (Cu, Zn, As, Pb, Cd, Fe, Mn) in all sections of Huayuan River was lower than the standard limit of Class III water in GB 3838-2002, and the overall water quality was good. The cross section fish Cd and As in the upstream border town are slightly polluted. In the lower reaches of Huayuan River, Pb and As were slightly polluted, while Cd was seriously polluted. The single heavy metal hazard coefficient (THQ) and the composite heavy metal hazard coefficient (TTHQ) of fish in Huayuan River are both less than 1, which indicates that the enrichment of heavy metals in fish in Huayuan River will not cause harm to human consumption. Conclusion The results of this study reflect the influence of water pollution degree on heavy metal enrichment of fish in Huayuan River to some extent, and provide reference and theoretical support for the assessment of ecological security, fish resource diversity and food safety of Huayuan River in this region.

Objective To discuss the dispersion and correlation of granite in Foshan, analyze the causes of the dispersion and the measures to reduce the dispersion. Methods 10 groups of granite samples from a place in Foshan were selected for laboratory tests of physical and mechanical properties, and the data were analyzed statistically. Results The water content, bulk density, particle density and uniaxial compressive strength of granites in this area have a certain correlation, and there are discretization. Conclusion Analysis of the correlation and discreteness of test results is helpful to improve the reference value of test data and provide theoretical support for engineering applications.

Objective This study was aimed at the accurate determination of heavy metals in water quality by inductively coupled plasma mass spectrometry (ICP-MS), so as to improve the analysis accuracy and provide scientific basis for water quality monitoring. Methods The water samples were collected for filtration and acidification. Agilent 7700x was used to detect lead, cadmium, arsenic and mercury according to EPA 6020B standard. The power, argon flow rate and sample introduction rate were optimized. Results The single factor analysis of variance showed that the optimized ICP-MS significantly improved the sensitivity and accuracy of heavy metal detection. RSD was less than 5% in repeated experiments, and the recovery rate was 95%~105%. Conclusion This study successfully improved the accuracy of water quality analysis, and the optimization method provided reliable technical support for environmental monitoring.

Water quality safety is the key to ensuring human health and sustainable social development. With the increase of pollutants and the upgrading of detection technology, multi-parameter analyzers play a core role in water quality detection. This article reveals the important role of multi-parameter analyzers in efficient and accurate assessment of water quality. Special attention was paid to its outstanding performance in the detection of heavy metals, toxic substances and microbial contamination, and its significant advantages such as high efficiency, automation, multi-parameter simultaneous detection and remote monitoring were detailed. The development trend of miniaturization, intelligence and networking of multi-parameter analysis instruments provides important technical support and scientific basis for improving the efficiency and accuracy of water quality detection, ensuring water quality safety, and promoting ecological protection and sustainable development. And provide a more rigorous and scientific reference basis for the design and implementation of similar testing projects.