University laboratory is the main place of experimental teaching and scientific research, which plays an important role in universities. The safety management of the laboratory is the guarantee of the efficient operation of the laboratory and the improvement of the level of teaching and research. Meanwhile, the laboratory is also a place where the potential high-risk accidents happened. Aiming at the problem in the laboratory safety management, we have improved the laboratory safety management measures to prevent and reduce the occurrence of laboratory safety accidents. This article mainly proposed the potential safety hazards and improvement strategies for the laboratory management, offering valuable insights for refence.

With the rapid development of China's economic market, the safety evaluation of mechanical and electrical products has become a key link for enterprises to enhance their competitiveness. Through the application of systematic functional risk assessment, the standardization and scientific nature of safety evaluation of mechanical and electrical products can be improved. This paper mainly analyzes the difference between mechanical and electrical product safety evaluation and general evaluation and the specific application of functional hazard assessment in mechanical and electrical product safety evaluation. The results show that functional hazard assessment can comprehensively and scientifically evaluate the safety performance of mechanical and electrical products, and provide strong support for the selection of products with higher cost performance. It also provides useful reference and guidance for practical application, and further promotes the development of safety evaluation of electromechanical products in our country.

Objective The application of quality control chart in the quantitative detection of Staphylococcus aureus in milk was discussed by collecting the routine detection process of Staphylococcus aureus in milk and testing the results of Staphylococcus aureus in quality control samples simultaneously. Methods Monitoring the detection data by utilizing the center line of the single value control chart and the moving range control chart, an upper warning limit, a lower warning limit, an upper control limit and a lower control limit, standard error and data point inside and outside the boundary of the range control chart are used to monitor and evaluate the laboratory detection process, and the status of the personnel, instruments and reagents in the experimental detection process is judged. Results By observing the range of test data and analyzing the distribution characteristics and changes of data, the results showed that single value control chart and moving range control chart could effectively monitor the detection process of Staphylococcus aureus in milk, and the data results were reliable. Conclusion The construction of the quality control chart provides an effective means of food hygiene quality control for laboratory testing of the project, and helps to promote the smooth development of the quality control work in the laboratory testing process.

This paper discusses the significance of the construction of open sharing platform for large instruments and equipment, and analyzes the main problems existing in the construction of large instrument sharing platform in local undergraduate colleges, such as insufficient investment funds, imperfect sharing mechanism, weak testing level and insufficient utilization of instruments and equipment. The paper puts forward some practical suggestions on the construction of the open sharing platform of large instruments and equipment by increasing the capital investment, improving the open sharing mechanism, assembling and strengthening the experimental technical team, and developing and mining the testing

Objective To explore the determination of trace glutathioneby resonance scattering spectral quenching method and improve thesensitivity of the method. Methods In the pH 3.0 phosphoric acid-boricacid-acetic acid buffer solution (BR buffer), $\mathrm{{Fe}}\left(\mathrm{{III}}\right)$ reacts with ${\mathrm{K}}_{4}\left\lbrack {\mathrm{{Fe}}{\left(\mathrm{{CN}}\right)}_{6}}\right\rbrack$ to form Prussian blue ion associates, and the system exhibits a strongresonance scattering effect at ${337}\mathrm{\;{nm}}$ . When glutathione isadded, the sulfhydryl group in glutathione molecules can reduce Fe(III)to Fe(II), causing quenching of the system and weakening the resonancescattering quenching effect. Results The linear regression equation forglutathione within the concentration range of 0.010 to ${2.0\mu }\mathrm{g}/\mathrm{{mL}}$ is ${\Delta l}= {299.77\rho }+{774.52}$ , with an ${r}^{2}$ of 0.9929 and a detection limit of ${0.0024\mu }\mathrm{g}/\mathrm{{mL}}$ . Conclusion This method is simple and highly sensitive, and satisfactoryresults are obtained when used for the determination of glutathione indrugs.

Water quality safety is the key to ensuring human health and sustainable social development. With the increase of pollutants and the upgrading of detection technology, multi-parameter analyzers play a core role in water quality detection. This article reveals the important role of multi-parameter analyzers in efficient and accurate assessment of water quality. Special attention was paid to its outstanding performance in the detection of heavy metals, toxic substances and microbial contamination, and its significant advantages such as high efficiency, automation, multi-parameter simultaneous detection and remote monitoring were detailed. The development trend of miniaturization, intelligence and networking of multi-parameter analysis instruments provides important technical support and scientific basis for improving the efficiency and accuracy of water quality detection, ensuring water quality safety, and promoting ecological protection and sustainable development. And provide a more rigorous and scientific reference basis for the design and implementation of similar testing projects.

Objective Gray mold is an important disease in thestrawberry production process, which seriously affects its yield andquality. This article aims to study the resistance of gray moldpathogens in different strawberry production areas in Zhejiang Provinceto fludioxonil, in order to clarify the current use status and futuremedication strategies of this fungicide. Methods This article uses themycelial growth rate method to conduct indoor toxicity testing on 184strains isolated from strawberry gray mold disease samples in 7 regionsof Zhejiang Province, in order to determine their sensitivity tofludioxonitril and count the frequency of occurrence of resistant andsensitive strains. Results The results showed that the strawberry graymold strain in Quzhou area had the highest sensitivity to fludioxonil,with an average ${\mathrm{{EC}}}_{50}$ value of ${0.014\mu }\mathrm{g}/\mathrm{{mL}}$ ,while the strawberry gray mold strain in Huzhou area had the lowestsensitivity to fludioxonil, with an average ${\mathrm{{EC}}}_{50}$ value of ${0.032\mu }\mathrm{g}/\mathrm{{mL}}$ and asensitivity baseline of ${0.018\mu}\mathrm{g}/\mathrm{{mL}}$ and the sensitive baseline value forthe whole province is ${0.018\mu}\mathrm{g}/\mathrm{{mL}}$ . Conclusion At present, a few lowresistant strains have appeared in the Zhejiang region, indicating thatthe strawberry gray mold fungus has developed certain resistance tofludioxonitril. The sensitivity baseline value has increased compared toprevious research results, but the overall level of drug resistance isstill controllable.

Objective Establish a ultra high performance liquidchromatography (UPLC) method for the simultaneous determination of sevenginsenosides Rg1, Re, Rf, Rb1, Rc, Rb2, and Rd in ginseng medicinalmaterials. Methods Using CAPCELL PAK ${\mathrm{C}}_{18}\mathrm{{MG}}\left({{2.0}\mathrm{\;{mm}}\times {150}\mathrm{\;{mm}},{2.0\mu}\mathrm{m}}\right)$ Chromatographic column with gradientelution of acetonitrile-0.05% phosphoric acid solution as mobile phase,flow rate of ${0.38}\mathrm{\;{mL}}\cdot {\mathrm{{min}}}^{-1}$ ,detection wavelength of ${203}\mathrm{\;{nm}}$ , column temperatureof ${30}^{\circ }\mathrm{C}$ , andinjection volume of ${1\mu}\mathrm{L}$ . Results All 7 ginsenosides can be completelyseparated and have a good linear relationship $\left({{r}^{2}> {0.999}}\right)$ withina certain linear concentration range, with an average recovery rate of ${97.22}\%\sim {104.56}\%$ ; Therelative standard deviation (RSD) is ${0.4}\%\sim {1.8}\%\left({n = 9}\right)$ ,and the precision RSD is ${0.57}\%\sim {1.42}\%$ . Conclusion Thismethod has strong specificity, excellent precision, good accuracy, andmore efficient detection process, and can be used for the determinationof seven ginsenosides in ginseng medicinal materials.

Objective To analyze the content of heavy metals in water and fish in Huayuan River. Methods Microwave digestion and inductively coupled plasma mass spectrometry (ICP-MS) were used to determine the heavy metal content of common freshwater fish such as Branchfish, Carassius elegans, Siniperca elegans and grass carp in Huayuan River. Results The content of heavy metals (Cu, Zn, As, Pb, Cd, Fe, Mn) in all sections of Huayuan River was lower than the standard limit of Class III water in GB 3838-2002, and the overall water quality was good. The cross section fish Cd and As in the upstream border town are slightly polluted. In the lower reaches of Huayuan River, Pb and As were slightly polluted, while Cd was seriously polluted. The single heavy metal hazard coefficient (THQ) and the composite heavy metal hazard coefficient (TTHQ) of fish in Huayuan River are both less than 1, which indicates that the enrichment of heavy metals in fish in Huayuan River will not cause harm to human consumption. Conclusion The results of this study reflect the influence of water pollution degree on heavy metal enrichment of fish in Huayuan River to some extent, and provide reference and theoretical support for the assessment of ecological security, fish resource diversity and food safety of Huayuan River in this region.

Objective This study was aimed at the accurate determination of heavy metals in water quality by inductively coupled plasma mass spectrometry (ICP-MS), so as to improve the analysis accuracy and provide scientific basis for water quality monitoring. Methods The water samples were collected for filtration and acidification. Agilent 7700x was used to detect lead, cadmium, arsenic and mercury according to EPA 6020B standard. The power, argon flow rate and sample introduction rate were optimized. Results The single factor analysis of variance showed that the optimized ICP-MS significantly improved the sensitivity and accuracy of heavy metal detection. RSD was less than 5% in repeated experiments, and the recovery rate was 95%~105%. Conclusion This study successfully improved the accuracy of water quality analysis, and the optimization method provided reliable technical support for environmental monitoring.