Objective Through the statistical analysis of the actual detection results of Down's disease screening and the pregnancy outcome of follow-up in Zhuhai, the health economics evaluation was carried out. Methods The data of 31967 pregnant women who underwent serum screening (SS) and non-invasive prenatal testing (NIPT) during the same pregnancy in Zhuhai City from 2018 to 2021 were retrospectively analyzed. The cost-benefit analysis was conducted according to 5 different screening strategies. Results Among 31,967 pregnancies, 38 were Down syndrome babies (including 3 pregnant women aged over 35 years), with a Down syndrome incidence of 1/841. Serological screening detected 1,649 cases of high risk of T21, of which 21 were true positives, with a positive predictive value of 1.27% and a detection rate of 55.3%; NIPT screening detected 49 cases of high risk of T21, 38 cases of Down syndrome babies, with a positive predictive value of 77.55% and a detection rate of 100%. The total cost generated by calculation strategy 4 was the lowest, about 27.44 million yuan. Conclusion NIPT can be used as primary screening test instead of serological screening method in prenatal Down's screening for secondary prevention and control of birth defects, which has great social and economic benefits.

Chenpi is an important Chinese herbal medicine and seasoning. Their quality and safety have drawn considerable concerns by consumers. The possible chemical risk substances such as pesticides, heavy metals and mycotoxins in Chenpi will have a negative impact on the health and safety of consumers. In order to reduce and avoid the quality and safety problems, researchers have utilized a variety of analytical techniques to develop novel analytical methods for the detection of hazardous chemical substances in Chenpi. The research progress on detection techniques for the quality and safety of Chenpi in recent years is reviewed in this paper, which is anticipating to provide a certain theoretical support and technical guidance for relevant researchers.

Based on the current status of university laboratory culture construction, this paper deeply analyzes the existing problems. Drawing on the concept of the management model of EHS (environment, health, safety) in management science, a generalized EHS model applicable to the management of university laboratories is proposed. Furthermore, an evaluation index system model (seven-force diagram) for laboratory safety culture construction is constructed based on the AHP (analytic hierarchy process) method, which can effectively enhance experimental safety and ensure standardized management of university laboratories.

This article summarizes the non-destructive testing techniques for concrete structures and their importance in evaluating the durability of concrete. With the aging of infrastructure, the demand for rapid and accurate evaluation and maintenance of concrete structures is increasing. Non destructive testing technology is highly valued for its ability to provide accurate evaluations without damaging the structure. The article introduces the main non-destructive testing methods, including ultrasonic testing, electromagnetic wave testing, and radiometric testing, and discusses in detail the application effects of these technologies in practical engineering. The advantages and disadvantages of each technology were also compared and analyzed. In the future, with the development of intelligence, integration, and portability, non-destructive testing technology will further improve detection efficiency and accuracy, and be widely used in long-term monitoring of infrastructure, providing technical support for extending the service life of structures and reducing maintenance costs.

Objective This study aims to evaluate the stability and repeatability of digital pressure gauges in laboratory environments, to verify their measurement accuracy in different pressure ranges and performance in long-term use, and to provide scientific basis for the calibration and application of digital pressure gauges. Methods The experiment adopted a multi-point and multiple measurement method, selecting three different pressure points of 0.1,0.3,0.6 MPa for testing. Ten repeated measurements were taken at each pressure point to evaluate the repeatability of the digital pressure gauge. Meanwhile, through long-term measurements every three months for one year, observe the stability performance of the digital pressure gauge during long-term use. The experimental environment conditions are strictly controlled, with a temperature maintained at${\left({20}\pm 2\right)}^{\circ}\mathrm{C}$and a relative humidity between${40}\%$and${60}\%$. Results The standard deviations of the digital pressure gauge at the three pressure points were 0.10088 , 0.30057 and 0.60087, respectively. The standard deviations were small and the repeatability was good. At the same time, during long-term use, the measurement values at each measurement point have a relatively small change amplitude, and the changes in range and average values are within the allowable error range, indicating that it has good long-term stability. Conclusion Digital pressure gauges exhibit high repeatability and stability in laboratory environments, making them suitable for high-precision pressure measurement applications. This study provides a scientific basis for the calibration and practical application of digital pressure gauges, and also provides a reference direction for the research and improvement of related equipment in the future.

This study will start with the current problems in the safety and management of multi campus university laboratories, and explore new methods and approaches for intelligent management and security system design of laboratories based on the perspective of the Internet of Things. We will use Internet information technology to build a resource sharing, fully open and efficient experimental teaching platform, build a laboratory management system based on the big data era, monitor the whole process before, during and after the experiment through the collection and analysis of data generated by the use and operation of various instruments and equipment, find problems in the experiment in time, carry out targeted guidance, effectively warn laboratory hazards, improve laboratory safety management efficiency, push laboratory management to a higher level, and achieve the win-win effect of talent training, scientific innovation, and safety management.

As an indispensable scientific research equipment in the construction of university laboratories, large instruments are the basis and guarantee for teaching and scientific research. The utilization rate of large instruments is also related to the formation and play of national scientific and technological innovation ability, which is of great significance to the construction of an innovative country. This paper explores and discusses the main problems existing in the management and sharing efficiency of large instruments in universities, and puts forward corresponding countermeasures to provide ideas for solving the management problems of large instruments in laboratories.

To explore the limitations of the low air pressure test methods for electronic and electrical products, and to propose ways to optimize and improve the test methods. To analyze the influence of low air pressure environment on the performance, reliability and life of electronic products, and to summarize the important role of low air pressure test in the reliability assessment of electronic products. From the four aspects of test equipment, test conditions, test point arrangement and data processing methods, suggestions are made to improve the low air pressure test methods. For the test equipment, it is proposed to adopt new vacuum pumps, high vacuum chamber materials, optimize the sealing structure, and introduce precise temperature control algorithms; for the test conditions, it is proposed to reasonably select the air pressure value and rate of change according to the product environment, match the temperature conditions, and take into account the test efficiency and failure incentives; for the test point layout, it is proposed to focus on the key devices and weak structures, and adopt suitable wiring materials and direction design; for the data processing method, it is proposed to improve the low air pressure test method. For the data processing method, it is suggested to introduce new methods such as machine learning and signal processing to explore the failure law and performance trend, and focus on the visualization of the analysis results. Strengthening the research on low air pressure test methods is of great significance to enhance the reliability of electronic products and promote their application in rail transportation, aerospace and other fields, which requires the joint efforts of industry, academia and research institutes.

Driven by the development of nanotechnology, silver nanomaterials are widely used in the field of sensing due to their catalytic performance, conductivity, and optical properties. The silver nano triangular sensing array has become a research hotspot in the field of biochemical substance detection, supported by its performance in multi-component simultaneous detection and high sensitivity. Based on this, this article summarizes the synthesis methods, characteristics, and research progress of sensing arrays of silver nano triangles, and focuses on the practical applications of colorimetric sensing arrays, surface enhanced Raman scattering, and other technologies in biochemical substance detection, providing useful references for research and practice in related fields.

Objective Judging the performance stability of atomic fluorescence spectrometer in the Laboratory. Methods We performed intermediate check to atomic fluorescence spectrometer. We test the detection limits, measurement repeatability, linear error and accuracy of the instrument for arsenic reference substances. Results Verifiable indicators are in line with the standard requirements. Conclusion This method is simple and feasible, and the performance of the atomic fluorescence spectrometer in the laboratory is stable.