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Comparison of detection methods for chlamydia trachomatis in the genital tract
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Yang TENG1, Ting-Ting JIANG2, Hai-Ling YE3, Yu-Ping WANG1, Xiang-Sheng CHEN2, You-Lin QIAO1, *
Laboratory Testing | 2024, 2(5) : 156 - 160
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Laboratory Testing | 2024, 2(5): 156-160
Evaluation and Analysis
Comparison of detection methods for chlamydia trachomatis in the genital tract
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Yang TENG1, Ting-Ting JIANG2, Hai-Ling YE3, Yu-Ping WANG1, Xiang-Sheng CHEN2, You-Lin QIAO1, *
Affiliations
  • 1 School of Population Medicine and Public Health Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100730 China
  • 2 Institute of Dermatology, Chinese Center for Disease Control and Prevention Chinese Academy of Medical Sciences Nanjing 210042 China
  • 3 Shenzhen Nanshan District Chronic Disease Prevention and Treatment Center Shenzhen 518000 China
Outline
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Objective Comparing two detection methods for chlamydial trachomatis in the genital tract (GeneXpertⓇ CT/NG and Roche® Cobas 4800 CT/NG), we summarize their respective advantages and disadvantages to provide references for the promotion and application of these two methods. Methods During a field survey conducted in a sample hospital, a convenience sampling method was employed to select 60 patients. Vaginal swabs were collected from these patients for testing using the GeneXpert® CT/NG system, while urine samples were collected for testing with the Roche® Cobas 4800 CT/NG system. Staff members were tasked with recording and compiling data related to the testing process, including the time taken for testing, the cost of testing, and the positive detection rates. This data was then used to compare the two testing methods. Results The testing time for Roche® Cobas 4800 CT/NG is 293 minutes, while the testing time for GeneXpertⓇ CT/NG is 92.95 minutes. In other words, the testing time for Roche® Cobas 4800 CT/NG is 3.15 times longer than that of GeneXpert® CT/NG; When the number of tests conducted in the sample hospital reaches 3000 cases, the cost of Roche® Cobas 4800 CT/NG testing is approximately 1/5 of that of GeneXpert® CT/NG testing. As the number of tests increases, when the volume reaches 200,000 cases, the unit cost of Roche® Cobas 4800 CT/NG testing is approximately 1/3 of the unit cost of GeneXpert® CT/NG testing; Among the 60 participants in this study, 11 cases of CT positive patients were detected by GeneXpert® CT/NG, with a CT positive rate of 0.183. Roche®Cobas 4800 CT/NG detected 10 cases, with a CT positive rate of 0.167. Conclusion The GeneXpert® CT/NG test has a significant time advantage, as it takes less time and provides faster results; The Roche® Cobas 4800 CT/NG test has a cost advantage, with lower detection costs; The GeneXpert® CT/ NG test has a higher positive detection rate.

genital chlamydia trachomatis  /  detection method  /  GeneXpert® CT/NG  /  Roche® Cobas 4800 CT/NG
Yang TENG, Ting-Ting JIANG, Hai-Ling YE, Yu-Ping WANG, Xiang-Sheng CHEN, You-Lin QIAO. Comparison of detection methods for chlamydia trachomatis in the genital tract[J]. Laboratory Testing, 2024 , 2 (5) : 156 -160 .
Year 2024 volume 2 Issue 5
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  • Online Date:2025-07-29
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Affiliations
    1 School of Population Medicine and Public Health Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100730 China
    2 Institute of Dermatology, Chinese Center for Disease Control and Prevention Chinese Academy of Medical Sciences Nanjing 210042 China
    3 Shenzhen Nanshan District Chronic Disease Prevention and Treatment Center Shenzhen 518000 China

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*QIAO You-Lin, Ph.D, Professor, School of Group Medicine and Public Health, Peking Union Medical College, Beijing 100730, China. E-mail:
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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