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Optimization of multi-component extraction process and evaluation of multi-system antioxidant activity of Mirabilis himalaica
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Yue-Ling WANG1, Zhuo-Ma ZHAXI2, Yong-Zhen WANG3, Peng-Fei QI1, Xue-Mei XU1, Jin-Cao YANG2, *
Laboratory Testing | 2024, 2(8) : 156 - 160
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Laboratory Testing | 2024, 2(8): 156-160
Evaluation and Analysis
Optimization of multi-component extraction process and evaluation of multi-system antioxidant activity of Mirabilis himalaica
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Yue-Ling WANG1, Zhuo-Ma ZHAXI2, Yong-Zhen WANG3, Peng-Fei QI1, Xue-Mei XU1, Jin-Cao YANG2, *
Affiliations
  • 1 Lanzhou Institute of Food and Drug Inspection and Testing Lanzhou 730050 China
  • 2 Gannan Tibetan Autonomous Prefecture Drug Inspection and Testing Center Hezuo 747000 China
  • 3 147th Hospital of the 8th Division of Xinjiang Production and Construction Corps Shihezi 832045 China
Outline
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Objective To optimize the ultrasonic extraction technologyof flavonoids, polyphenols and saponins from Mirabilis himalaica, and toevaluate their antioxidant activities. Methods Based on the singlefactor tests of ethanol concentration, liquid-solid ratio, extractiontemperature and extraction time, Box-Behnken response surface method wasused to optimize the extraction process of flavonoids, polyphenols andsaponins. The antioxidant activity of DPPH, ABTS, superoxide anion andhydroxyl radical was investigated in vitro. Results The optimizedultrasonic extraction technology was ${60}\%$ ethanol concentration, ${30}\mathrm{\;{mL}}/\mathrm{g}$ liquid-solid ratio, 50℃ extractiontemperature and 55 min extraction time. The extracts had strongscavenging effect on free radicals. Conclusion It is proved that theoptimized ultrasonic extraction technology of flavonoids, polyphenolsand saponins from Mirabilis himalaica is reasonable, and the extractshave antioxidant activity in vitro.

Mirabilis himalaica  /  ultrasonic extraction technology  /  in vitro antioxidant activity
Yue-Ling WANG, Zhuo-Ma ZHAXI, Yong-Zhen WANG, Peng-Fei QI, Xue-Mei XU, Jin-Cao YANG. Optimization of multi-component extraction process and evaluation of multi-system antioxidant activity of Mirabilis himalaica[J]. Laboratory Testing, 2024 , 2 (8) : 156 -160 .
  • Drug Research Project of Gansu Provincial Drug Administration(2021GSMPA006)
  • Lanzhou Science and Technology Bureau Lanzhou Science and Technology Plan Project(2023-ZD-232)
Year 2024 volume 2 Issue 8
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  • Online Date:2025-07-29
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Funding
Drug Research Project of Gansu Provincial Drug Administration(2021GSMPA006)
Lanzhou Science and Technology Bureau Lanzhou Science and Technology Plan Project(2023-ZD-232)
Affiliations
    1 Lanzhou Institute of Food and Drug Inspection and Testing Lanzhou 730050 China
    2 Gannan Tibetan Autonomous Prefecture Drug Inspection and Testing Center Hezuo 747000 China
    3 147th Hospital of the 8th Division of Xinjiang Production and Construction Corps Shihezi 832045 China

Corresponding:

*YANG Jin-Cao, Chief Pharmacist, Gannan Tibetan Autonomous Prefecture Drug Inspection and Testing Center, Hezuo 747000, China. E-mail:
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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