Objective To analyze the effectiveness of enzyme-linkedimmunosorbent assay (ELISA) and colloidal gold test in the detection ofhuman immunodeficiency virus (HIV) antibodies. Methods From January 2022to January 2024,50 cases of sentinel surveillance and contact populationof confirmed AIDS patients in our unit were selected as the observationtarget, and they were detected by ELISA and colloidal gold testrespectively, and the difference of patients’ detection results wasanalyzed. Results Among the 50 key populations, 36 were ultimatelydiagnosed and 14 were negative, which is the gold standard for thisstudy. The diagnostic effect of enzyme-linked immunosorbent assay issignificantly better than that of colloidal gold assay, and thedifference is statistically significant $\left({P <{0.05}}\right)$ . Conclusion The enzyme-linked immunosorbent assay (ELISA) is significantly moreeffective in HIV antibody detection than colloidal gold assay, and isworthy of being the preferred detection method.

AIDS  /  AIDS virus  /  enzyme linked immunosorbent assay  /  colloidal gold test  /  diagnostic effectiveness