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Objective To investigate the clinical features, pathogens and drug resistance of elderly patients with traumatic infective endophthalmitis (PTIE). Methods 76 elderly patients (76 eyes) with PTIE treated in our hospital from January 2023 to January 2024 were retrospectively analyzed. Clinical characteristics and pathogenic bacteria of patients were collected and their drug resistance was analyzed. Results The clinical features of elderly PTIE were related to the location of the wound in area I (84.21%), the penetration injury of intraocular foreign body (60.52%) and the presence of metal foreign body (48.68%). The fungal detection rate in patients who were above 75 years old was higher than that in patients${60}\sim {75}$years old$\left({P <{0.05}}\right)$. In 76 elderly patients with PTIE, a total of 56 pathogenic bacteria were isolated, including 45 Gram-positive bacteria, 8 Gram-negative bacteria and 3 kinds of fungi. Among Gram-positive bacteria, the highest resistance of Staphylococcus epidermidis was penicillin (100%) and gentamicin (88.89%), and the highest resistance of Saprophytic staphylococcus was penicillin (88.89%) and erythromycin (88.89%). Among Gram-negative bacteria, the highest resistance was amikacin (100%) and ampicillin (100%) in Pseudomonas aeruginosa, and ampicillin (100%) in Klebsiella pneumoniae. Conclusion The distribution of pathogenic bacteria in elderly PTIE patients was affected by the location of the injured mouth, the type of trauma, the type of foreign body in the eye and age factors, among which Gram-positive bacteria was the main infection type, Staphylococcus epidermidis was the most common. Staphylococcus epidermidis has a high resistance to penicillin, in contrast to ampicillin and imipenem are relatively low resistance.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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