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Probiotic Microencapsulation: Delivery Mechanisms, Material Development, and Applications in Food Systems
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Zhaosen YUAN1, Chunyan JIA1, Ming WU1, Ning CHEN2, Na ZHANG1, Xiaofei LIU1, *
Science and Technology of Food Industry | 2026, 47(18) : 580 - 592
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Science and Technology of Food Industry | 2026, 47(18): 580-592
• Frontier Reviews •
Probiotic Microencapsulation: Delivery Mechanisms, Material Development, and Applications in Food Systems
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Zhaosen YUAN1, Chunyan JIA1, Ming WU1, Ning CHEN2, Na ZHANG1, Xiaofei LIU1, *
Affiliations
  • 1College of Food Engineering, Harbin University of Commerce, Harbin 150028, China
  • 2College of Pharmacy, Harbin University of Commerce, Harbin 150028, China
Published: 2026-09-15 doi: 10.13386/j.issn1002-0306.2025080123
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Probiotic microencapsulation technology is essential for enhancing the gastrointestinal delivery efficiency and the targeted colonization capacity of live bacterial strains, as different materials and fabrication methods enable the construction of microcapsules with distinct characteristics. This review systematically examines the delivery mechanisms, material systems, and advancements in food applications of probiotic microencapsulation. In terms of the delivery mechanism, it begins with an elaboration of multiscale encapsulation techniques such as extrusion, internal emulsification, and microfluidic technology, highlighting its advantages and applicable context in delivery mechanisms. In the field of materials science, the structural-functional properties and protective efficacy of polysaccharides, proteins, and intelligent responsive wall materials are analyzed. At the application level, it summarizes the key influencing factors and current application status of microcapsules in dairy products, fruit and vegetable beverages, and functional dietary supplements. The review clarifies the compatibility patterns between encapsulation technologies, such as extrusion, and various wall materials, demonstrating their potential to enhance probiotic stress resistance and improve food functionality. It also reveals the gap between theoretical development and industrial application in this field, providing valuable insights for industry-academia-research collaboration and precise regulation of microbial communities. Finally, the review envisions future research needs, including the development of low-cost, eco-friendly wall materials, personalized strain-material compatibility strategies, and innovations in large-scale continuous manufacturing processes, to facilitate the transition of probiotic microencapsulation from laboratory-scale research to industrial implementation.

probiotics  /  microencapsulation  /  wall material design  /  mechanism of action  /  product application
袁照森, 贾春艳, 吴鸣, 陈宁, 张娜, 刘晓飞. 益生菌微胶囊化技术:递送机制、材料开发与食品领域应用进展. 食品工业科技, 2026 , 47 (18) : 580 -592 . DOI: 10.13386/j.issn1002-0306.2025080123
Zhaosen YUAN, Chunyan JIA, Ming WU, Ning CHEN, Na ZHANG, Xiaofei LIU. Probiotic Microencapsulation: Delivery Mechanisms, Material Development, and Applications in Food Systems[J]. Science and Technology of Food Industry, 2026 , 47 (18) : 580 -592 . DOI: 10.13386/j.issn1002-0306.2025080123
Year 2026 volume 47 Issue 18
142
68
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doi: 10.13386/j.issn1002-0306.2025080123
  • Receive Date:2025-08-13
  • Online Date:2026-10-24
  • Published:2026-09-15
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  • Received:2025-08-13
Affiliations
    1College of Food Engineering, Harbin University of Commerce, Harbin 150028, China
    2College of Pharmacy, Harbin University of Commerce, Harbin 150028, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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