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Advances in Nereis virens-derived Bioactive Peptides: Preparation and Bioactivity
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Huiying ZHU, Zhilu ZENG, Yanping DENG, Jia MAO, Yanglin HUA*, Ping HE*
Science and Technology of Food Industry | 2026, 47(11) : 479 - 486
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Science and Technology of Food Industry | 2026, 47(11): 479-486
• Reviews •
Advances in Nereis virens-derived Bioactive Peptides: Preparation and Bioactivity
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Huiying ZHU, Zhilu ZENG, Yanping DENG, Jia MAO, Yanglin HUA*, Ping HE*
Affiliations
  • College of Food Science and Engineering, Guangdong Ocean University, Yangjiang 529500, China
Published: 2026-06-01 doi: 10.13386/j.issn1002-0306.2025050201
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As a keystone species in estuarine zones, Nereis virens carries ecological and economic value. Its body wall is rich in high-quality animal protein (over 60%), and the products obtained after enzymatic hydrolysis exhibit multiple functions, making it a research hotspot. Enzymatic hydrolysis is the core technology to prepare the corresponding bioactive peptides, and the bioactivity of which can be significantly enhanced by optimal enzyme selection and process optimization. After multi-stage purification and functional validation, the enzymatically hydrolyzed Nereis virens peptides have been proved with multi-target bioactivities, including antioxidant activity, ACE-inhibitory activity, antitumor activity and immunomodulatory activity, etc. This paper systematically reviews the nutritional composition and current state of research status on Nereis virens, particularly focusing on the preparation methods and functional activities of the bioactive peptides. The aim is to provide a theoretical foundation for the sustainable exploitation and multi-domain applications of Nereis virens resources.

Nereis virens  /  Nereis virens peptide  /  preparation technology  /  functional activity
朱慧莹, 曾志鲁, 邓燕萍, 卯佳, 华洋林, 贺萍. 沙蚕及其来源生物活性肽的研究进展:制备与生物活性. 食品工业科技, 2026 , 47 (11) : 479 -486 . DOI: 10.13386/j.issn1002-0306.2025050201
Huiying ZHU, Zhilu ZENG, Yanping DENG, Jia MAO, Yanglin HUA, Ping HE. Advances in Nereis virens-derived Bioactive Peptides: Preparation and Bioactivity[J]. Science and Technology of Food Industry, 2026 , 47 (11) : 479 -486 . DOI: 10.13386/j.issn1002-0306.2025050201
Year 2026 volume 47 Issue 11
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doi: 10.13386/j.issn1002-0306.2025050201
  • Receive Date:2025-05-21
  • Online Date:2026-10-22
  • Published:2026-06-01
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  • Received:2025-05-21
Affiliations
    College of Food Science and Engineering, Guangdong Ocean University, Yangjiang 529500, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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