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Advances in the Study of Human Milk Oligosaccharides: Structure, Analysis, and Industrial Applications
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Lunwei WU1, 2, Guoxia DUAN1, 2, *, Lijun LIU1, 2, Chunxia LIU2, Huili GONG1, Jing CHEN2, Xiaoli WU1, 2, Zhiyong LÜ1, 2
Science and Technology of Food Industry | 2026, 47(14) : 477 - 490
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Science and Technology of Food Industry | 2026, 47(14): 477-490
• Reviews •
Advances in the Study of Human Milk Oligosaccharides: Structure, Analysis, and Industrial Applications
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Lunwei WU1, 2, Guoxia DUAN1, 2, *, Lijun LIU1, 2, Chunxia LIU2, Huili GONG1, Jing CHEN2, Xiaoli WU1, 2, Zhiyong LÜ1, 2
Affiliations
  • 1Inner Mongolia Yili Industrial Group Co., Ltd., Hohhot 010100, China
  • 2Key Laboratory of Cattle and Sheep Milk and Meat Products Risk Control and Key Technology, State Administration for Market Regulation, Hohhot 010100, China
Published: 2026-07-15 doi: 10.13386/j.issn1002-0306.2025060006
Outline
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Human milk oligosaccharides (HMOs) are abundant components in human milk, playing a pivotal role in shaping the characteristic gut microbiota and regulating immune function in infants and other populations. This review elaborates on the structure, content, detection methods, biological functions, and food applications of HMOs, while contrasting the differences between animal milk oligosaccharides and human milk oligosaccharides. Furthermore, it explores compounding strategies for infant formula and analyzes regulatory advancements in this field. By synthesizing these insights, this review aims to provide researchers and developers in the food industry with a practical, forward-looking, and instructive reference to advance the application of HMOs in the food sector.

human milk oligosaccharides  /  structure  /  content  /  detection technology  /  biofunctional properties  /  application
武伦玮, 段国霞, 刘丽君, 刘春霞, 宫慧丽, 陈静, 吴晓莉, 吕志勇. 母乳低聚糖研究进展:结构特征、检测技术与产业化应用. 食品工业科技, 2026 , 47 (14) : 477 -490 . DOI: 10.13386/j.issn1002-0306.2025060006
Lunwei WU, Guoxia DUAN, Lijun LIU, Chunxia LIU, Huili GONG, Jing CHEN, Xiaoli WU, Zhiyong LÜ. Advances in the Study of Human Milk Oligosaccharides: Structure, Analysis, and Industrial Applications[J]. Science and Technology of Food Industry, 2026 , 47 (14) : 477 -490 . DOI: 10.13386/j.issn1002-0306.2025060006
Year 2026 volume 47 Issue 14
128
54
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doi: 10.13386/j.issn1002-0306.2025060006
  • Receive Date:2025-06-01
  • Online Date:2026-10-22
  • Published:2026-07-15
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  • Received:2025-06-01
Affiliations
    1Inner Mongolia Yili Industrial Group Co., Ltd., Hohhot 010100, China
    2Key Laboratory of Cattle and Sheep Milk and Meat Products Risk Control and Key Technology, State Administration for Market Regulation, Hohhot 010100, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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