Home Journals Articles Updates About
CN
image
收藏切换
Research Progress on Lactoferrin-Protein Interaction Complexes and Their Impact on Immune Regulation
收藏切换
Ruilan CHAI1, Haoming WANG2, Cong HAN1, Gaoping ZHAO3, 4, Rifu XUE4, Dong ZHANG1, *
Science and Technology of Food Industry | 2026, 47(17) : 587 - 596
Less
收藏切换
Science and Technology of Food Industry | 2026, 47(17): 587-596
• Reviews •
Research Progress on Lactoferrin-Protein Interaction Complexes and Their Impact on Immune Regulation
Full
Ruilan CHAI1, Haoming WANG2, Cong HAN1, Gaoping ZHAO3, 4, Rifu XUE4, Dong ZHANG1, *
Affiliations
  • 1Grass Industry College, Inner Mongolia Agricultural University, Hohhot 010000, China
  • 2College of Life Sciences, Inner Mongolia Agricultural University, Hohhot 010000, China
  • 3National Dairy Technology Innovation Center, Hohhot 010000, China
  • 4Inner Mongolia Saikexing Livestock Seed Industry and Breeding Biotechnology Research Institute Co., Ltd., Hohhot 010000, China
Published: 2026-09-01 doi: 10.13386/j.issn1002-0306.2025080240
Outline
收藏切换

Milk serves as a crucial medium of nutrition and immune protection for newborns. Its proteins exhibit a holistic mechanism of action: rather than functioning in isolation, they assemble into complexes through mutual interactions. These complexes demonstrate superior efficacy in nutrient delivery and immune protection compared to their isolated counterparts. This paper reviews advances in understanding the interaction mechanisms of milk-derived proteins, encompassing forms such as charge interaction, domain-specific binding, and cofactor-mediated association. It further examines the immunoregulatory effects of these protein complexes, including direct antimicrobial and antiviral activities, regulation of immune cell function and inflammatory responses, enhancement of intestinal barrier integrity and flora balance, and promotion of immune system maturation. The analysis of current research challenges and future directions provides a new perspective for developing novel functional foods and immunomodulators.

milk protein  /  interaction  /  mechanism  /  interactive composite  /  immunoregulation
柴瑞兰, 王浩名, 韩聪, 赵高平, 薛日夫, 张东. 乳源蛋白互作复合体及其影响免疫调节的研究进展. 食品工业科技, 2026 , 47 (17) : 587 -596 . DOI: 10.13386/j.issn1002-0306.2025080240
Ruilan CHAI, Haoming WANG, Cong HAN, Gaoping ZHAO, Rifu XUE, Dong ZHANG. Research Progress on Lactoferrin-Protein Interaction Complexes and Their Impact on Immune Regulation[J]. Science and Technology of Food Industry, 2026 , 47 (17) : 587 -596 . DOI: 10.13386/j.issn1002-0306.2025080240
Appendix
Less
Year 2026 volume 47 Issue 17
150
65
Cite this Article
BibTeX
Article Info
doi: 10.13386/j.issn1002-0306.2025080240
  • Receive Date：2025-08-22
  • Online Date：2026-10-24
  • Published：2026-09-01
Article Data
Affiliations
History
  • Received：2025-08-22
Affiliations
    1Grass Industry College, Inner Mongolia Agricultural University, Hohhot 010000, China
    2College of Life Sciences, Inner Mongolia Agricultural University, Hohhot 010000, China
    3National Dairy Technology Innovation Center, Hohhot 010000, China
    4Inner Mongolia Saikexing Livestock Seed Industry and Breeding Biotechnology Research Institute Co., Ltd., Hohhot 010000, China
References
Share
https://castjournals.cast.org.cn/joweb/spgykj/EN/10.13386/j.issn1002-0306.2025080240
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT
Links
Articles
Latest Articles
Most Read
Collections
Updates
Events
News
Multimedia
About
About Us
Contact
No. 86 Xueyuan South Road, Haidian District, Beijing
100081
010-62662699(Operation and Technical Support)
qkjq@cast.org.cn

Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House