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Preparation of Curcumin Derivative-doped Silica Nano-photosensitizers and Its Photodynamic Inactivation Performance
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Jiawen LI1, Ran WEI1, Long JIAO1, *, Xiaoye ZHANG2, *, Xiang CHEN3, Bin ZHANG1, 4
Science and Technology of Food Industry | 2026, 47(13) : 152 - 159
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Science and Technology of Food Industry | 2026, 47(13): 152-159
• Research and Investigation •
Preparation of Curcumin Derivative-doped Silica Nano-photosensitizers and Its Photodynamic Inactivation Performance
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Jiawen LI1, Ran WEI1, Long JIAO1, *, Xiaoye ZHANG2, *, Xiang CHEN3, Bin ZHANG1, 4
Affiliations
  • 1Key Laboratory of Health Risk Factors for Seafood of Zhejiang Province, College of Food Science and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China
  • 2School of Naval Architecture and Maritime, Zhejiang Ocean University, Zhoushan 316022, China
  • 3Zhoushan Institute for Food and Drug Inspection and Testing, Zhoushan 316012, China
  • 4Pisa Marine Graduate School, Zhejiang Ocean University, Zhoushan 316022, China
Published: 2026-07-01 doi: 10.13386/j.issn1002-0306.2025070264
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In order to improve the photodynamic inactivation (PDI) effect of curcumin, three kinds of nano-photosensitizers SiO2@X-Cur were prepared by covalently coupling halogenated curcumin derivatives X-Cur (X=F, Cl or Br) into silica by Stöber method. The successful preparation of SiO2@X-Cur was confirmed by spectral characterization, doping amount determination and microstructure analysis. The results showed that SiO2@F-Cur had the best comprehensive performance, and its saturated solubility in water was 308.33 μg/mL, which was 3.75-fold that of curcumin. The singlet oxygen generation capability was particularly outstanding, achieving an indicator decay rate of 63% within 60 s. The light stability was considerably higher better than other samples (the fluorescence retention rate was 42.86% after irradiation for 30 min), and it also had high covalent doping stability. In addition, SiO2@F-Cur had the best PDI effect on Vibrio parahaemolyticus. Under the condition of 2.0 mg/mL concentration and blue LED irradiation for 20 min, the total number of colonies decreased to 0.09 lg (CFU/mL). Therefore, SiO2@F-Cur prepared in this study is an efficient and novel PDI nano-photosensitizer, which provides new ideas and research basis for guiding the development of novel aquatic product preservatives.

curcumin derivative  /  silica nanoparticles  /  Stöber method  /  photodynamic inactivation  /  Vibrio parahaemolyticus
李嘉雯, 魏然, 焦龙, 张晓晔, 陈翔, 张宾. 姜黄素衍生物掺杂二氧化硅纳米光敏剂的制备及其光动力灭活性能. 食品工业科技, 2026 , 47 (13) : 152 -159 . DOI: 10.13386/j.issn1002-0306.2025070264
Jiawen LI, Ran WEI, Long JIAO, Xiaoye ZHANG, Xiang CHEN, Bin ZHANG. Preparation of Curcumin Derivative-doped Silica Nano-photosensitizers and Its Photodynamic Inactivation Performance[J]. Science and Technology of Food Industry, 2026 , 47 (13) : 152 -159 . DOI: 10.13386/j.issn1002-0306.2025070264
Appendix
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Year 2026 volume 47 Issue 13
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Article Info
doi: 10.13386/j.issn1002-0306.2025070264
  • Receive Date：2025-07-23
  • Online Date：2026-10-24
  • Published：2026-07-01
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History
  • Received：2025-07-23
Affiliations
    1Key Laboratory of Health Risk Factors for Seafood of Zhejiang Province, College of Food Science and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China
    2School of Naval Architecture and Maritime, Zhejiang Ocean University, Zhoushan 316022, China
    3Zhoushan Institute for Food and Drug Inspection and Testing, Zhoushan 316012, China
    4Pisa Marine Graduate School, Zhejiang Ocean University, Zhoushan 316022, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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