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Investigation into the Synergistic Enhancement of Astaxanthin Nanodispersion Stability by Chitosan-Ca2+ and Its Underlying Mechanism
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Tiantian HAN1, Ke YE1, Tianhang QIU1, Lu LUO2, Xiao'e CHEN1, Jing ZHANG1, *, Ming CHENG1, *
Science and Technology of Food Industry | 2026, 47(16) : 86 - 94
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Science and Technology of Food Industry | 2026, 47(16): 86-94
• Research and Investigation •
Investigation into the Synergistic Enhancement of Astaxanthin Nanodispersion Stability by Chitosan-Ca2+ and Its Underlying Mechanism
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Tiantian HAN1, Ke YE1, Tianhang QIU1, Lu LUO2, Xiao'e CHEN1, Jing ZHANG1, *, Ming CHENG1, *
Affiliations
  • 1College of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 136000, China
  • 2School of Naval Architecture and Maritime, Zhejiang Ocean University, Zhoushan 136000, China
Published: 2026-08-15 doi: 10.13386/j.issn1002-0306.2025070186
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To enhance the stability and bioavailability of astaxanthin (AST), soy protein isolates (SPI) were used as the raw material to prepare SPI/chitosan (CS) composite nanoparticles for the encapsulation of AST. The study investigated the effect of CS on the encapsulation efficiency of AST. Ca2+ were then introduced as stabilizer to investigate their effect on the stability of the SPI/CS/AST nanodispersion and to elucidate the underlying mechanism. The results demonstrated that at a CS concentration of 0.6 mg/mL, the encapsulation efficiency of AST reached 59.57%, representing an 11% increase compared to samples without CS. Under this CS concentration, when Ca2+ was added at 0.2 mg/mL, the AST encapsulation efficiency further rose to 73.55%, a 20% improvement over samples without Ca2+. Moreover, at a storage temperature of 4 ℃, the retention rate of AST increased by 14% with Ca2+ addition. Under ultraviolet irradiation, 0.2 mg/mL Ca2+ provided the most effective protection for AST within the nanodispersion, enhancing retention by 23% compared to those without Ca2+. Furthermore, the retention rates of encapsulated AST in simulated gastric and intestinal fluids reached 78.35% and 67.18%, respectively. Ultraviolet and fluorescence spectroscopy analysis revealed that Ca2+ enhanced stability by influencing hydrogen bonds and hydrophobic interactions in the nanodispersion through ionic bridging, electrostatic neutralization, and conformational regulation. In summary, this study successfully established a highly stable AST nano-delivery system through the synergistic effect of SPI/CS composite wall materials and Ca2+, providing a theoretical basis for the application of AST in the development of functional foods.

astaxanthin  /  Ca2+  /  chitosan  /  nanodispersion  /  stability
韩田田, 叶可, 裘天航, 罗路, 陈小娥, 张晶, 程铭. 壳聚糖-Ca2+协同增强虾青素纳米分散体的稳定性及其机制探究. 食品工业科技, 2026 , 47 (16) : 86 -94 . DOI: 10.13386/j.issn1002-0306.2025070186
Tiantian HAN, Ke YE, Tianhang QIU, Lu LUO, Xiao'e CHEN, Jing ZHANG, Ming CHENG. Investigation into the Synergistic Enhancement of Astaxanthin Nanodispersion Stability by Chitosan-Ca2+ and Its Underlying Mechanism[J]. Science and Technology of Food Industry, 2026 , 47 (16) : 86 -94 . DOI: 10.13386/j.issn1002-0306.2025070186
Year 2026 volume 47 Issue 16
89
41
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doi: 10.13386/j.issn1002-0306.2025070186
  • Receive Date:2025-07-17
  • Online Date:2026-10-24
  • Published:2026-08-15
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  • Received:2025-07-17
Affiliations
    1College of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 136000, China
    2School of Naval Architecture and Maritime, Zhejiang Ocean University, Zhoushan 136000, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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