Home Journals Articles Updates About
CN
image
收藏切换
Structural Characteristics, in Vitro Activity, and Regulatory Mechanism on Gut Microbiota of Alpiniaoxyphylla Oligosaccharides
收藏切换
Meng WANG1, 2, Jinmei HU2, Fengzhen YOU2, Fengchuan MA2, Yunping PENG2, 3, Siming ZHU2, *, Junlin WU2, *
Science and Technology of Food Industry | 2026, 47(10) : 139 - 149
Less
收藏切换
Science and Technology of Food Industry | 2026, 47(10): 139-149
• Research and Investigation •
Structural Characteristics, in Vitro Activity, and Regulatory Mechanism on Gut Microbiota of Alpiniaoxyphylla Oligosaccharides
Full
Meng WANG1, 2, Jinmei HU2, Fengzhen YOU2, Fengchuan MA2, Yunping PENG2, 3, Siming ZHU2, *, Junlin WU2, *
Affiliations
  • 1Key Laboratory of Biological Resources and Ecology of Pamirs Plateauin Xinjiang Uygur Autonomous Region, College of Life and Geographic Sciences, Kashi University, Kashi 844000, China
  • 2School of Food Science and Engineering, Guangdong Ocean University, Yangjiang 529500, China
  • 3Guangzhou Wondfo Health Science and Technology Co., Ltd., Guangzhou 510640, China
Published: 2026-05-15 doi: 10.13386/j.issn1002-0306.2025060074
Outline
收藏切换

To investigate the structure of Alpinia oxyphylla Miq. oligosaccharides (MC) and their impact on human gut microbiota, MC was extracted and purified using ultrasound-assisted high-voltage pulsed electric fields. Its structural characteristics were analyzed using Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), and scanning electron microscopy (SEM). Its in vitro antioxidant and hypoglycemic activities, as well as its regulatory mechanism on the intestinal flora were investigated. Results showed that the extracted MC was a glucose homopolymer (100% glucose monosaccharide composition) with a molecular weight of 2461 Da. The β-glycosidic bond configuration of MC was confirmed by FT-IR spectroscopy, with characteristic peaks observed at 1656 cm−1 and 1623 cm−1. A hierarchical structure characterized by coexisting crystalline and amorphous domains within the β-glucan backbone was demonstrated through XRD and SEM analyses. These structural features constituted a structural basis for targeting gut microbiota. In vitro activity assays indicated that MC exhibited negligible antioxidant activity, but demonstrated notable hypoglycemic activity. Fecal fermentation experiments demonstrated that MC markedly increased the abundance of Bacillota, reduced Bacteroidetes, and enriched the genera Ligilactobacillus and Weissella, thereby regulating and improving intestinal function. This study provides a theoretical foundation for developing Alpinia oxyphylla Miq. oligosaccharides as prebiotics.

Alpinia oxyphylla oligosaccharides  /  structural characterization  /  in vitro activity  /  human gut microbiota
王猛, 胡金梅, 游凤珍, 马凤川, 彭运平, 朱思明, 吴军林. 益智仁低聚糖的结构特征、体外活性及其对肠道菌群的调控机制. 食品工业科技, 2026 , 47 (10) : 139 -149 . DOI: 10.13386/j.issn1002-0306.2025060074
Meng WANG, Jinmei HU, Fengzhen YOU, Fengchuan MA, Yunping PENG, Siming ZHU, Junlin WU. Structural Characteristics, in Vitro Activity, and Regulatory Mechanism on Gut Microbiota of Alpiniaoxyphylla Oligosaccharides[J]. Science and Technology of Food Industry, 2026 , 47 (10) : 139 -149 . DOI: 10.13386/j.issn1002-0306.2025060074
Appendix
Less
Year 2026 volume 47 Issue 10
116
46
Cite this Article
BibTeX
Article Info
doi: 10.13386/j.issn1002-0306.2025060074
  • Receive Date：2025-06-09
  • Online Date：2026-10-24
  • Published：2026-05-15
Article Data
Affiliations
History
  • Received：2025-06-09
Affiliations
    1Key Laboratory of Biological Resources and Ecology of Pamirs Plateauin Xinjiang Uygur Autonomous Region, College of Life and Geographic Sciences, Kashi University, Kashi 844000, China
    2School of Food Science and Engineering, Guangdong Ocean University, Yangjiang 529500, China
    3Guangzhou Wondfo Health Science and Technology Co., Ltd., Guangzhou 510640, China
References
Share
https://castjournals.cast.org.cn/joweb/spgykj/EN/10.13386/j.issn1002-0306.2025060074
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT
Links
Articles
Latest Articles
Most Read
Collections
Updates
Events
News
Multimedia
About
About Us
Contact
No. 86 Xueyuan South Road, Haidian District, Beijing
100081
010-62662699(Operation and Technical Support)
qkjq@cast.org.cn

Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House