Full
Outline
To investigate the migration characteristics and compliance risks of 19 kinds of organophosphorus esters (OPEs) in milk powder packaging materials, and conduct targeted food safety risk assessment.
This study selected 12 typical milk powder packaging materials [including canned, bagged, and production-use polyethylene (PE) bags], determined the migration amounts of 19 kinds of target OPEs by liquid chromatography-tandem mass spectrometry (LC-MS/MS), and conducted a targeted risk assessment by integrating hazard analysis and exposure levels.
OPEs were detected in 7 out of 12 materials, with 3 kinds of target compounds identified, namely tri-n-butyl phosphate (TnBP), triphenyl phosphate (TPhP), and tris(2,4-di-tert-butylphenyl) phosphate (AO168O). Among them, AO168O had the highest detection rate (41.67%) with a maximum migration amount of 0.02970 mg/kg. Compliance evaluation showed that TnBP met the limit requirements of GB 9685—2016 National food safety standard-Uses of additives in food contact materials and articles, while there were no explicit relevant regulations that clearly authorize the use of TPhP and AO168O. Risk assessment indicated that the exposure risk quotients of OPEs ranged from 0.088% to 1.650% for the general population and from 0.789% to 14.850% for infants and young children, with the overall risk being at an acceptable level.
This study clarifies the migration status and risk levels of OPEs in milk powder packaging materials, providing data reference for milk powder production and packaging enterprises to establish a full-chain OPEs risk investigation and traceability mechanism and focus on controlling the migration risk of AO168O.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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