Full
Outline
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), a novel technique for microbial detection and identification, exhibits tremendous application potential in the detection and identification of Salmonella. It boasts prominent strengths including rapid detection, high accuracy and low cost, yet it has inherent limitations in discriminating Salmonella species, subspecies and serovars. This paper systematically reviewed relevant research papers published from 2005 to 2025, with a special focued on advances in applying MALDI-TOF MS to differentiate Salmonella species, subspecies and serovars. Rapid identification of Salmonella species, subspecies and common serovars could be realized by screening specific protein biomarkers. Integration of genomic sequence data with algorithms such as decision trees could further boost the accuracy of serovar identification.Currently, MALDI-TOF MS had been widely deployed in food safety monitoring, clinical diagnosis, antimicrobial resistance testing and epidemiological investigations, achieving high accuracy for genus-level identification of Salmonella. Despite persistent challenges in fine-scale typing of Salmonella, continuous database optimization and technological innovations will make MALDI-TOF MS a vital tool for Salmonella typing and identification, providing robust technical support for food safety surveillance, clinical diagnosis and epidemiological tracing.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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