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Research progress on chloropropanol residues in paper and paperboard materials intended for food contact
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Wei LIU1, Rui YUAN2, Zi-Yi WANG1, Rui-Ying TU1, Rong ZHAO1, Sai FAN1, Jie GAO3, Dao-Yuan YANG3, *, Hai-Xia SUI3
Journal of Food Safety & Quality | 2026, 17(9) : 94 - 100
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Journal of Food Safety & Quality | 2026, 17(9): 94-100
• Special Topic: Detection of Harmful Substances in Food Contact Materials •
Research progress on chloropropanol residues in paper and paperboard materials intended for food contact
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Wei LIU1, Rui YUAN2, Zi-Yi WANG1, Rui-Ying TU1, Rong ZHAO1, Sai FAN1, Jie GAO3, Dao-Yuan YANG3, *, Hai-Xia SUI3
Affiliations
  • 1.Beijing Center for Disease Prevention and Control, Beijing 100013, China
  • 2.Beijing Dongcheng District Center for Disease Control and Prevention/Centre for Public Health Emergency Management Innovation, Beijing 100050, China
  • 3.China National Center for Food Safety Risk Assessment, Beijing 100022, China
doi: 10.19812/j.cnki.jfsq11-5956/ts.20251229004
Outline
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Chloropropanols (e.g., 3-monochloro-1,2-propanediol) are non-intentionally added contaminants in paper and paperboard materials intended for food contact. They exhibit multiple toxicological effects. These compounds primarily originate from side reactions occurring during the synthesis of wet-strength agents based on polyamide-epichlorohydrin resins, which are commonly used in papermaking processes. If not effectively removed, chloropropanols may migrate from food packaging materials into food, posing potential health risks to consumers. China has already established relevant national food safety standards that set maximum limits for chloropropanol residues in paper and paperboard intended for food contact. Similar risk management measures have also been implemented internationally. This article reviewed the pollution sources, formation mechanisms and supervision measures of chloropropanols in paper and paperboard materials, and provided an overview of existing research on chloropropanol residues in paper and paperboard intended for food contact. The aim is to enhance awareness among industry stakeholders and the general public regarding the health risks associated with these contaminants, thereby supporting further research and improving risk management to better protect consumer health.

chloropropanols  /  paper and paperboard materials  /  wet-strength agents  /  food contact materials  /  risk management
刘伟, 袁蕊, 王子怡, 屠瑞莹, 赵榕, 范赛, 高洁, 杨道远, 隋海霞. 食品接触用纸和纸板材料中氯丙醇残留研究进展. 食品安全质量检测学报, 2026 , 17 (9) : 94 -100 . DOI: 10.19812/j.cnki.jfsq11-5956/ts.20251229004
Wei LIU, Rui YUAN, Zi-Yi WANG, Rui-Ying TU, Rong ZHAO, Sai FAN, Jie GAO, Dao-Yuan YANG, Hai-Xia SUI. Research progress on chloropropanol residues in paper and paperboard materials intended for food contact[J]. Journal of Food Safety & Quality, 2026 , 17 (9) : 94 -100 . DOI: 10.19812/j.cnki.jfsq11-5956/ts.20251229004
Appendix
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Year 2026 volume 17 Issue 9
5
1
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Article Info
doi: 10.19812/j.cnki.jfsq11-5956/ts.20251229004
  • Receive Date：2025-12-29
  • Online Date：2026-11-05
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  • Received：2025-12-29
Funding
Affiliations
    1.Beijing Center for Disease Prevention and Control, Beijing 100013, China
    2.Beijing Dongcheng District Center for Disease Control and Prevention/Centre for Public Health Emergency Management Innovation, Beijing 100050, China
    3.China National Center for Food Safety Risk Assessment, Beijing 100022, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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