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As a worldwide medicinal and edible homologous plant, Allium sativum L. has the functions of antitumor, prevention and treatment of cardiovascular diseases and anti-pathogenic microorganisms. Studies have shown that many active ingredients in Allium sativum L. exert antitumor effects mainly by inhibiting tumor cell proliferation, regulating signaling pathways to inhibit migration and invasion, inducing tumor cell apoptosis, and arresting cell cycle. At the same time, the Allium sativum L. active ingredient also enhances the antitumor effect of other drugs through its combination with other drugs. This article reviewed the research on the antitumor effect and mechanism of Allium sativum L. active ingredients in the past 30 years, as well as the effects of Allium sativum L. active ingredients in combination with other drugs, this provides an important theoretical basis and application reference for the study of the antitumor action mechanism of active ingredients in Allium sativum L. and the development of innovative drugs.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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