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Etiological study of a food poisoning incident caused by venison
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Hao-Jia MA1, *, Xin-Xin XU1, Zhou ZHU1, Hong-He LIU1, Ying-Xin CHEN2
Journal of Food Safety & Quality | 2025, 16(16) : 247 - 253
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Journal of Food Safety & Quality | 2025, 16(16): 247-253
• Food Analysis and Detection •
Etiological study of a food poisoning incident caused by venison
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Hao-Jia MA1, *, Xin-Xin XU1, Zhou ZHU1, Hong-He LIU1, Ying-Xin CHEN2
Affiliations
  • 1 Shenzhen Center for Disease Control and Prevention, Shenzhen 518055, China
  • 2 Shenzhen Guangming Center for Disease Control and Prevention, Shenzhen 518106, China
Published: 2025-08-25 doi: 10.19812/j.cnki.jfsq11-5956/ts.20250415002
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Objective To analyze the cause of a complex food poisoning incident using a combination of non-targeted and targeted methods based on mass spectrometry. Methods Suspected contaminated food and blood samples from the cases were collected. After sample preparation, a high-resolution mass spectrometry non-targeted method was used for toxin screening, and a triple quadrupole mass spectrometry targeted detection method was applied for the quantitative analysis of xylazine in the samples. Results Xylazine was detected in both the suspected contaminated food (raw and fried venison) and the serum samples of 3 cases. The concentrations in raw and fried venison were 3.0 μg/kg and 395.9 μg/kg, while the concentrations in the cases’ serum were 47.0, 16.0 and 15.6 ng/mL, respectively. Conclusion This incident is confirmed as xylazine poisoning caused by venison ingestion. First, through epidemiological investigation, the scope for identifying the cause of poisoning can be quickly determined. The non-targeted method provides accurate evidence for clinical treatment, aiding in the diagnosis and management of such events. At the same time, the targeted quantitative analysis of samples also provides a basis for the formulation of drug use standards in farmed animals in the future.

food poisoning  /  xylazine  /  non-targeted screening  /  epidemiological investigation
Hao-Jia MA, Xin-Xin XU, Zhou ZHU, Hong-He LIU, Ying-Xin CHEN. Etiological study of a food poisoning incident caused by venison[J]. Journal of Food Safety & Quality, 2025 , 16 (16) : 247 -253 . DOI: 10.19812/j.cnki.jfsq11-5956/ts.20250415002
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doi: 10.19812/j.cnki.jfsq11-5956/ts.20250415002
  • Receive Date：2025-04-15
  • Online Date：2026-01-13
  • Published：2025-08-25
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  • Received：2025-04-15
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    1 Shenzhen Center for Disease Control and Prevention, Shenzhen 518055, China
    2 Shenzhen Guangming Center for Disease Control and Prevention, Shenzhen 518106, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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