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Study on the uric acid-lowering effects of postbiotic powder in hyperuricemia
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Ao WANG1, Wu LIANG1, 2, Tian-Min FU1, Yun-Qi SUN1, Qing-Qing LIU1, Xue-Mei HAN1, *
Journal of Food Safety & Quality | 2025, 16(6) : 26 - 33
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Journal of Food Safety & Quality | 2025, 16(6): 26-33
• Special Topic: Application of Fermentation Technology in Food •
Study on the uric acid-lowering effects of postbiotic powder in hyperuricemia
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Ao WANG1, Wu LIANG1, 2, Tian-Min FU1, Yun-Qi SUN1, Qing-Qing LIU1, Xue-Mei HAN1, *
Affiliations
  • 1. Tianjin InnoOrigin Biological Technology Co., Ltd., Tianjin 300301, China
  • 2. Tianjin Key Laboratory of Edible Probiotics, Tianjin 300301, China
Published: 2025-03-25 doi: 10.19812/j.cnki.jfsq11-5956/ts.20241219004
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Objective To investigate the uric acid-lowering effects of compound postbiotic powder in hyperuricemia. Methods In vitro experiments verified that the metabiotic powder had 2 kinds of effects: Inhibiting xanthine oxidase (XOD) activity and degrading uric acid, and then establishing a rat hyperuricemia model, and giving postbiotic powder treatment, respectively, the changes in body weight, joint growth, serum uric acid (UA) content, serum XOD activity, liver and kidney function, and total cholesterol (TC) in blood lipids, triglyceride (TG) level were compared. Results The sample significantly reduced the serum UA content, serum urea nitrogen (BUN), creatinine (Cr) and TC levels in rats with hyperuricemia. It could effectively reduce the activities of serum XOD, aspartate aminotransferase (AST) and alanine aminotransferase (ALT). Conclusion Postbiotic powder has the effect of lowering uric acid, and also has a certain therapeutic effect on liver and kidney injury and dyslipidemia caused by hyperuricemia, and the therapeutic effect is positively correlated with the intake of postbiotic powder.

postbiotic  /  hyperuricemia  /  xanthine oxidase  /  uric acid
Ao WANG, Wu LIANG, Tian-Min FU, Yun-Qi SUN, Qing-Qing LIU, Xue-Mei HAN. Study on the uric acid-lowering effects of postbiotic powder in hyperuricemia[J]. Journal of Food Safety & Quality, 2025 , 16 (6) : 26 -33 . DOI: 10.19812/j.cnki.jfsq11-5956/ts.20241219004
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Year 2025 volume 16 Issue 6
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doi: 10.19812/j.cnki.jfsq11-5956/ts.20241219004
  • Receive Date：2024-12-19
  • Online Date：2025-07-19
  • Published：2025-03-25
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  • Received：2024-12-19
Affiliations
    1. Tianjin InnoOrigin Biological Technology Co., Ltd., Tianjin 300301, China
    2. Tianjin Key Laboratory of Edible Probiotics, Tianjin 300301, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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