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Optimization of extraction and purification process of Cinnamomum cassia Presl polyphenols and study on its in vitro activities
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Li-Ping DANG1, 2, Hui-Xian HUANG1, 2, Jian CHEN1, 2, Chun-Wei JIAO1, 2, Jian-Wen LIU1, 2, Yi-Zhen XIE1, 2, *
Journal of Food Safety & Quality | 2026, 17(18) : 111 - 122
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Journal of Food Safety & Quality | 2026, 17(18): 111-122
• Special Topic: Functional Foods and Functional Components •
Optimization of extraction and purification process of Cinnamomum cassia Presl polyphenols and study on its in vitro activities
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Li-Ping DANG1, 2, Hui-Xian HUANG1, 2, Jian CHEN1, 2, Chun-Wei JIAO1, 2, Jian-Wen LIU1, 2, Yi-Zhen XIE1, 2, *
Affiliations
  • 1.Guangdong Yuewei Biotechnology Co., Ltd., Zhaoqing 526000, China
  • 2.Guangdong Yuewei Edible Fungi Technology Co., Ltd., Guangzhou 510663, China
doi: 10.19812/j.cnki.jfsq11-5956/ts.20260415007
Outline
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Objective

To investigate the extraction and purification processes of Cinnamomum cassia polyphenols and assess its in vitro biological activities.

Methods

A water extraction process combined with microfiltration and ultrafiltration membrane separation was employed to prepare a high-polyphenol, low-coumarin Cinnamomum cassia polyphenol extract (CPE).

Results

The CPE contained 48.3% polyphenols and 0.022 mg/g coumarin. Compared with conventional aqueous extracts, the polyphenol content of CPE increased by 213.5%; the total content of procyanidin B1 and B2 increased by 148.7%, and the coumarin content decreased by 77.08%. In vitro experiments demonstrated that,compared with conventional aqueous extracts, CPE showed significantly stronger scavenging capacities for 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2’-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) radical cation(ABTS+), along with improved iron chelating ability and total reducing power. CPE exhibited stronger inhibitory activity against α-amylase and α-glucosidase.

Conclusion

The extraction and purification processes established in this study greatly improve the purity of Cinnamomum cassia polyphenols, and the obtained CPE exhibits stronger in vitro antioxidant activity and inhibitory capacity against carbohydrate digestive enzymes.

Cinnamomum cassia Presl polyphenols  /  component analysis  /  antioxidant activity  /  enzyme inhibitory activity
党荔萍, 黄惠娴, 陈建, 焦春伟, 刘健文, 谢意珍. 肉桂多酚的提取纯化工艺优化及其体外活性研究. 食品安全质量检测学报, 2026 , 17 (18) : 111 -122 . DOI: 10.19812/j.cnki.jfsq11-5956/ts.20260415007
Li-Ping DANG, Hui-Xian HUANG, Jian CHEN, Chun-Wei JIAO, Jian-Wen LIU, Yi-Zhen XIE. Optimization of extraction and purification process of Cinnamomum cassia Presl polyphenols and study on its in vitro activities[J]. Journal of Food Safety & Quality, 2026 , 17 (18) : 111 -122 . DOI: 10.19812/j.cnki.jfsq11-5956/ts.20260415007
Appendix
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Year 2026 volume 17 Issue 18
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Article Info
doi: 10.19812/j.cnki.jfsq11-5956/ts.20260415007
  • Receive Date：2026-04-15
  • Online Date：2026-11-05
Article Data
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History
  • Received：2026-04-15
Funding
Affiliations
    1.Guangdong Yuewei Biotechnology Co., Ltd., Zhaoqing 526000, China
    2.Guangdong Yuewei Edible Fungi Technology Co., Ltd., Guangzhou 510663, China
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https://castjournals.cast.org.cn/joweb/spaq/EN/10.19812/j.cnki.jfsq11-5956/ts.20260415007
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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