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Research progress on the chemical diversity, tissue distribution and biological activities of polymethoxylated flavonoids in Citrus
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Chun-Yan WU, You WU, Zhou-Jie ZHU, Shang-Kun FENG*
Journal of Food Safety & Quality | 2026, 17(12) : 145 - 154
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Journal of Food Safety & Quality | 2026, 17(12): 145-154
• Special Topic: Functional Foods and Functional Components •
Research progress on the chemical diversity, tissue distribution and biological activities of polymethoxylated flavonoids in Citrus
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Chun-Yan WU, You WU, Zhou-Jie ZHU, Shang-Kun FENG*
Affiliations
  • College of Agriculture and Bioengineering, Taizhou Vocational College of Science & Technology, Taizhou 318020, China
doi: 10.19812/j.cnki.jfsq11-5956/ts.20260319002
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Polymethoxyflavonoids (PMFs) in Citrus fruits are a class of natural compounds with unique chemical structures and significant biological activities. This paper systematically reviewed the chemical diversity, tissue distribution and germplasm variations of citrus PMFs, as well as their biological activities in antioxidant,antiproliferative/antitumor activities, antibacterial, immunomodulatory and antiviral effects, and summarizes preliminary structure-activity relationships. Building on this, it analyzed core issues in current research, such as insufficient target identification, unclear in vivo metabolic processes, and low bioavailability, and provided prospects for future research directions, including the application of multi-omics technologies, target elucidation and novel delivery systems, aiming to provide references for the in-depth development and functional product creation of citrus PMFs.

polymethoxylated flavonoids  /  Citrus  /  tissue distribution  /  chemical diversity  /  biological activities
吴春艳, 吴悠, 祝洲杰, 冯尚坤. 柑橘中多甲氧基类黄酮成分的化学多样性、组织分布与生物活性研究进展. 食品安全质量检测学报, 2026 , 17 (12) : 145 -154 . DOI: 10.19812/j.cnki.jfsq11-5956/ts.20260319002
Chun-Yan WU, You WU, Zhou-Jie ZHU, Shang-Kun FENG. Research progress on the chemical diversity, tissue distribution and biological activities of polymethoxylated flavonoids in Citrus[J]. Journal of Food Safety & Quality, 2026 , 17 (12) : 145 -154 . DOI: 10.19812/j.cnki.jfsq11-5956/ts.20260319002
Year 2026 volume 17 Issue 12
9
1
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doi: 10.19812/j.cnki.jfsq11-5956/ts.20260319002
  • Receive Date:2026-03-19
  • Online Date:2026-11-05
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  • Received:2026-03-19
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    College of Agriculture and Bioengineering, Taizhou Vocational College of Science & Technology, Taizhou 318020, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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