Polymethoxyflavonoids (PMFs) in Citrus fruits are a class of natural compounds with unique chemical structures and significant biological activities. This paper systematically reviewed the chemical diversity, tissue distribution and germplasm variations of citrus PMFs, as well as their biological activities in antioxidant,antiproliferative/antitumor activities, antibacterial, immunomodulatory and antiviral effects, and summarizes preliminary structure-activity relationships. Building on this, it analyzed core issues in current research, such as insufficient target identification, unclear in vivo metabolic processes, and low bioavailability, and provided prospects for future research directions, including the application of multi-omics technologies, target elucidation and novel delivery systems, aiming to provide references for the in-depth development and functional product creation of citrus PMFs.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |