Full
Outline
To study the toxicological safety of arabica coffea pulp.
The acute oral toxicity tests, 90-day oral toxicity tests, teratogenicity tests and 3 genetic toxicity tests were conducted on arabica coffea pulp in accordance with GB 15193.3—2014 National food safety standard-Acute oral toxicity test and other toxic test methods.
No obvious signs of poisoning symptoms appeared when the experimental animals were given 15.0 g/(kg·BW) of arabica coffea pulp in one time, and there was no death during the observation period, which indicated that the lethal dose of 50% of coffee pulp for experimental animals was more than 15.0 g/(kg·BW);during the 90-day oral toxicity test in rats, the rats were able to move freely, their growth and development were in good condition, and there was no death, there was no obvious change in rats, the blood routine and other indicators were within the normal value range, and there was no statistically significant difference (P>0.05); no specific damage and typical pathological and histological changes were observed in anatomical and pathological studies; at a dose of 10.0 g/(kg·BW), the rats showed no obvious embryotoxicity and teratogenic effects; the results of the 3 genetic toxicity tests were negative, and noagenic effects were seen.
The arabica coffea pulp has no genetic, no teratogenic and no toxic under the given test conditions, and has high safety in food development.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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