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Research progress on the preparation and application of whey protein-based microcapsules
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Yu-Han MENG1, *, Jing CHAO1, Jian KANG1, He XIE1, Kai-Sheng WANG1, Chen-Guo NIE1, Shen-Yuan ZHANG2
Journal of Food Safety & Quality | 2025, 16(12) : 245 - 252
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Journal of Food Safety & Quality | 2025, 16(12): 245-252
Food Processing and Technology
Research progress on the preparation and application of whey protein-based microcapsules
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Yu-Han MENG1, *, Jing CHAO1, Jian KANG1, He XIE1, Kai-Sheng WANG1, Chen-Guo NIE1, Shen-Yuan ZHANG2
Affiliations
  • 1 School of Science and Chemical Engineering, Ningxia Institute of Technology, Shizuishan 753000, China
  • 2 Pharmaron (Ningbo) Technology Development Co., Ltd., Ningbo 315000, China
Published: 2025-06-25 doi: 10.19812/j.cnki.jfsq11-5956/ts.20250213004
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In recent years, microcapsule technology has shown broad application prospects in food science and biomedicine due to its protection and controlled release characteristics of active ingredients. Among a variety of wall materials, whey protein has become a promising candidate due to its natural non-toxicity, biocompatibility and biodegradability. This paper first provided an overview of the putamen structure of whey protein-based microcapsules. Secondly, this paper mainly discussed the modification methods of whey protein wall materials: Building composite wall materials with other biological macromolecules; structural modification by physical or chemical methods, as well as improvement of interface properties by Maillard reaction. This paper analyzed the technical characteristics of spray drying, freeze drying and complex coacervation methods and their effects on the properties of whey protein-based microcapsules. The results showed that the embedding rate and stability of microcapsules could be significantly improved by precisely regulating the process parameters. Finally, in the field of application, whey protein-based microcapsules could not only effectively protect the activity of probiotics and achieve targeted delivery of active substances, but also showed application potential in biomedical fields such as controlled drug delivery systems and wound dressings.

whey protein  /  microcapsules  /  preparation
Yu-Han MENG, Jing CHAO, Jian KANG, He XIE, Kai-Sheng WANG, Chen-Guo NIE, Shen-Yuan ZHANG. Research progress on the preparation and application of whey protein-based microcapsules[J]. Journal of Food Safety & Quality, 2025 , 16 (12) : 245 -252 . DOI: 10.19812/j.cnki.jfsq11-5956/ts.20250213004
Year 2025 volume 16 Issue 12
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doi: 10.19812/j.cnki.jfsq11-5956/ts.20250213004
  • Receive Date:2025-02-13
  • Online Date:2026-01-13
  • Published:2025-06-25
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  • Received:2025-02-13
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    1 School of Science and Chemical Engineering, Ningxia Institute of Technology, Shizuishan 753000, China
    2 Pharmaron (Ningbo) Technology Development Co., Ltd., Ningbo 315000, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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