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Study on edible safety evaluation of HuangqiSangyeYuzhu granules
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Yue ZHANG1, 2, #, Xiang-Tao NIU2, #, Juan REN2, Shi-Meng ZHOU2, Jing-Wen E2, Bo-Wen CHEN2, Han-Xia LIU1, 2, *, Xiang LI1, 2, *
Journal of Food Safety & Quality | 2025, 16(12) : 280 - 286
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Journal of Food Safety & Quality | 2025, 16(12): 280-286
• Food Nutrition and Functional Foods •
Study on edible safety evaluation of HuangqiSangyeYuzhu granules
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Yue ZHANG1, 2, #, Xiang-Tao NIU2, #, Juan REN2, Shi-Meng ZHOU2, Jing-Wen E2, Bo-Wen CHEN2, Han-Xia LIU1, 2, *, Xiang LI1, 2, *
Affiliations
  • 1 China Academy of Quality and Inspection & Testing, Beijing 100176, China
  • 2 Comprehensive Testing Center, China Academy of Inspection and Quarantine, Beijing 100123, China
Published: 2025-06-25 doi: 10.19812/j.cnki.jfsq11-5956/ts.20250208005
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Objective To evaluate the edible safety of HuangqiSangyeYuzhu granules. Methods The edible safety of HuangqiSangyeYuzhu granules was comprehensively evaluated by acute oral toxicity test, 3 genotoxicity tests, and 28 d oral toxicity test. Results The results of acute oral toxicity test showed no abnormality in the test animals, and the maximum tolerated dose of HuangqiSangyeYuzhu granules was greater than 30.0 g/kg·BW, which was practically non-toxic substance. The results of bacterial reverse mutation test, mammalian erythrocyte micronucleus test and spermatogonial chromosome aberration test were negative, indicating that the HuangqiSangyeYuzhu granules had no genotoxicity. During the 28 d oral toxicity test, the rats growed well, and no signs of toxicity were observed, and no adverse effects associated with HuangqiSangyeYuzhu Granules were seen in blood routine, blood biochemistry, and pathology indices, and the no observed adverse effect level was 10.0 g/kg·BW. Conclusion HuangqiSangyeYuzhu granules have edible safety within the dosage range of this experiment.

HuangqiSangyeYuzhu granules  /  health food  /  toxicological safety evaluation
Yue ZHANG, Xiang-Tao NIU, Juan REN, Shi-Meng ZHOU, Jing-Wen E, Bo-Wen CHEN, Han-Xia LIU, Xiang LI. Study on edible safety evaluation of HuangqiSangyeYuzhu granules[J]. Journal of Food Safety & Quality, 2025 , 16 (12) : 280 -286 . DOI: 10.19812/j.cnki.jfsq11-5956/ts.20250208005
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Year 2025 volume 16 Issue 12
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doi: 10.19812/j.cnki.jfsq11-5956/ts.20250208005
  • Receive Date：2025-02-08
  • Online Date：2026-01-13
  • Published：2025-06-25
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  • Received：2025-02-08
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    1 China Academy of Quality and Inspection & Testing, Beijing 100176, China
    2 Comprehensive Testing Center, China Academy of Inspection and Quarantine, Beijing 100123, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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