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Research progress on determination of pollutants in food by liquid chromatography-high resolution mass spectrometry
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Min SU, Hong-Li LI, Ya-Min BAI, Da-Liang HUANG, Yuan LIU, Yan-Lei WU*
Journal of Food Safety & Quality | 2025, 16(4) : 44 - 52
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Journal of Food Safety & Quality | 2025, 16(4): 44-52
• Special Topic: Research and Detection of Pesticide and Veterinary Drug Residue •
Research progress on determination of pollutants in food by liquid chromatography-high resolution mass spectrometry
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Min SU, Hong-Li LI, Ya-Min BAI, Da-Liang HUANG, Yuan LIU, Yan-Lei WU*
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  • Chongqing Institute for Food and Drug Control, Key Laboratory of Condiment Supervision Technology, State Administration for Market Regulation, Chongqing 401121, China
Published: 2025-02-25 doi: 10.19812/j.cnki.jfsq11-5956/ts.20241218008
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There are many types of pollutants in food, and exposure involves multiple stages such as raw material, processing, transportation, storage, packaging, and sales. With the improvement of people's requirements for the healthy, nutritive and safe condiments, the pollutants in food have received more and more attention. Liquid chromatography-high resolution mass spectrometry (LC-HRMS) combines the separation ability of liquid chromatography with the advantages of high resolution mass spectrometry, such as wide mass range, fast scanning speed, and high sensitivity, making it an important means in the field of food safety analysis. This review summarized the technical characteristics of quadrupole-time of flight mass spectrometry and quadrupole-orbitrap mass spectrometry, as well as the research progress in the detection of pollutants in food using LC-HRMS technology over the past 5 years. The article focused on the application of LC-HRMS in the targeted and non-targeted determination of pesticides residues, veterinary drugs and their metabolites, food additives, illegal additives and mycotoxins, and prospected the development trend. Aiming to provide reference for the detection of pollutants in food in the future.

liquid chromatography-high resolution mass spectrometry  /  pesticide residues  /  veterinary drugs and their metabolites  /  illegal additive  /  food additives  /  mycotoxin
Min SU, Hong-Li LI, Ya-Min BAI, Da-Liang HUANG, Yuan LIU, Yan-Lei WU. Research progress on determination of pollutants in food by liquid chromatography-high resolution mass spectrometry[J]. Journal of Food Safety & Quality, 2025 , 16 (4) : 44 -52 . DOI: 10.19812/j.cnki.jfsq11-5956/ts.20241218008
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Year 2025 volume 16 Issue 4
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doi: 10.19812/j.cnki.jfsq11-5956/ts.20241218008
  • Receive Date：2024-12-18
  • Online Date：2025-07-21
  • Published：2025-02-25
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  • Received：2024-12-18
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    Chongqing Institute for Food and Drug Control, Key Laboratory of Condiment Supervision Technology, State Administration for Market Regulation, Chongqing 401121, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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