Traditional Chinese medicine is an important cultural and ecological resource in China. Relevant national or local regulations and standards set clear requirements for the packaging label design of traditional Chinese medicine, creating hard constraints that guide traditional Chinese medicine packaging design. creating hard constraints that guide traditional Chinese medicine packaging design. Under these circumstances, the packaging design information for traditional Chinese medicine was organized, a packaging box template that complies with these constraints was created, and a design environment with hard constraints was established. Using the packaging design of “Jiangzhong Jianwei Xiaoshi Tablets” as an example, the existing packaging box was studied as the research object. Eye-tracking technology was employed to capture eye movement data on all six faces of the packaging box and its unfolded view. Key indicators, such as fixation time and heat maps, were used to analyze image attention and the importance of drug information. The current packaging information layout was systematically evaluated, and directions for improvement were proposed. Finally, through design empowerment, the drug information and layout were re-matched and arranged, producing a packaging design plan that guides traditional Chinese medicine packaging design to achieve efficient optimization and innovation of visual information under standardized conditions.