Weibo is an important channel for science popularization. This paper selects 14 mainstream science popularization bloggers as research samples and uses Python to collect information, takes into account micro-blog communication index, and interactive data, and finally analyzes the development, trends, and characteristics of science popularization bloggers. The research finds that: science popularization micro-blogs are on the rising development, there are big differences among different bloggers, and there are endlessly rising stars of bloggers. The spread of science popularization micro-blog relies on the social network between bloggers and fans, bloggers and bloggers. The types of micro-blogs, manifestations, content, styles, interaction might be important factors affecting the effectiveness of science popularization. In a nutshell, suggestions are given concerning how science popularization micro-blogs can effectively play the role of science communication.