At present, the paradigm of science popularization is undergoing a profound transformation from one-way output to participatory and interactive models. In this transition, the high-quality development of science popularization has an increasingly prominent demand for scene-driven innovation. From both theoretical and practical perspectives, this paper systematically analyzes the coupling logic between science popularization and scene theory. On this basis, it proposes four science popularization models derived from‘science popularization+scene’ and ‘scene + science popularization’. First, scenified science popularization reconstructs the production scene of scientific knowledge through technical means, transforming abstract scientific content into perceptible embodied experiences for the audience. Second, popularized scenes embed scientific elements into social spaces such as shopping malls and communities, activating the science popularization potential of non science contexts. Third, scenic popularization achieves the integration of multiple attributes of scenes through functional superposition and spatiotemporal reorganization. Fourth, scene-based science popularization promotes the integration of scientific spirit and daily practice through a context-constructed communication paradigm, thereby providing new ideas and methods for science popularization practice.