This study aims to conduct a research on college students’ perception on nuclear power and attitudes toward it. Focus group discussions and questionnaires are employed to investigate students from ten universities in Guangzhou city, including their self-perception and real knowledge of nuclear power, attitudes toward it, and which form and channel they prefer to use to access information having to do with science popularization. Results reveal that College students have limited knowledge of nuclear power, but the majority of them have positive attitudes toward it. The most reliable information sources to them are experts in the field of nuclear power, research institutions and regulators. University students prefer to gain more information about safety of nuclear power through interesting documentary. Moreover, descriptive analysis, statistical comparison, explorative analysis and other methods are used to analyze differences in gender, major and region. Factors influencing students’ attitudes toward nuclear power are examined. Implications of study findings for future science popularization and energy decision-makers engagedin the task of transforming College students’ attitudes toward nuclearpower are also discussed.