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Role of C-type lectin-like receptor 2 in thrombosis
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Shi-Xue Xu1, 2, Yang Yang3, Yang-Lan He1, 2, Xing-Shun Qi1, *
Medical Journal of Chinese People’s Liberation Army | 2021, 46(4) : 410 - 413
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Medical Journal of Chinese People’s Liberation Army | 2021, 46(4): 410-413
• Review •
Role of C-type lectin-like receptor 2 in thrombosis
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Shi-Xue Xu1, 2, Yang Yang3, Yang-Lan He1, 2, Xing-Shun Qi1, *
Affiliations
  • 1Department of Gastroenterology, General Hospital of Northern Theater Command, Shenyang 110840, China
  • 2Graduate School of China Medical University, Shenyang 110013, China
  • 3Faculty of Life Sciences, Northwest University, Xi'an 710069, China
Published: 2021-04-28 doi: 10.11855/j.issn.0577-7402.2021.04.15
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C-type lectin-like receptor 2 (CLEC-2) is a member of the cell surface receptor C-type lectin superfamily. CLEC-2 expressed in platelet surface is a platelet activatory receptor based on the immune receptor tyrosine activation motif, which can participate in platelet activation and aggregation by binding to its ligand. This physiological process can prevent excessive blood loss in the body, but is also the pathological basis of many thromboembolic diseases. CLEC-2 and its ligands are involved in the pathophysiological processes such as atherosclerosis, inflammation thrombotic state, maintenance of vascular integrity, and cancer-related thrombosis. The important role of CLEC-2 in the thrombosis process has been reviewed in present paper from the four aspects mentioned above.

C-type lectin-like receptor 2  /  thrombosis  /  atherosclerosis  /  deep venous thrombosis  /  cancer-related thrombosis
Shi-Xue Xu, Yang Yang, Yang-Lan He, Xing-Shun Qi. Role of C-type lectin-like receptor 2 in thrombosis[J]. Medical Journal of Chinese People’s Liberation Army, 2021 , 46 (4) : 410 -413 . DOI: 10.11855/j.issn.0577-7402.2021.04.15
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Article Info
doi: 10.11855/j.issn.0577-7402.2021.04.15
  • Receive Date：2020-12-29
  • Online Date：2025-12-26
  • Published：2021-04-28
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History
  • Received：2020-12-29
  • Revised：2021-03-19
Affiliations
    1Department of Gastroenterology, General Hospital of Northern Theater Command, Shenyang 110840, China
    2Graduate School of China Medical University, Shenyang 110013, China
    3Faculty of Life Sciences, Northwest University, Xi'an 710069, China

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表12种不同金属材料的力学参数
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Number of
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Number of
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小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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