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Research progress of relationship between serum ferritin and hepatic disease
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Zhi-Lin Sha, Shao-Hua Song, Guo-Shan Ding*
Medical Journal of Chinese People’s Liberation Army | 2021, 46(2) : 181 - 185
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Medical Journal of Chinese People’s Liberation Army | 2021, 46(2): 181-185
• Review •
Research progress of relationship between serum ferritin and hepatic disease
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Zhi-Lin Sha, Shao-Hua Song, Guo-Shan Ding*
Affiliations
  • Department of Organ Transplantation, Changzheng Hospital Affiliated to Naval Military Medical University, Shanghai 200003, China
Published: 2021-02-28 doi: 10.11855/j.issn.0577-7402.2021.02.12
Outline
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As a crucial microelement of human body, iron is involved in many important physiological processes. Serum ferritin (SF) is the main form of protein for iron storage, and regulates the storage and metabolism of iron. Although detection of ferritin has been applied for clinical use for a long time, some biological properties of ferritin still remain controversial, including its tissue origin, secretory pathway, interactions with receptors and cellular effects. Although many researches paid attention to the relationship between the changes of ferritin and liver diseases, the cut-off points of ferritin used varies in different studies, which hinders the consistency analysis of the results of different studies. It is urgent to explore and establish uniform standard for the parameter of ferritin, so as to better elucidate the iron status in the body reflected by changes in ferritin. This paper reviews the in vivo metabolic process of iron, the structural composition and pathophysiological function of ferritin, and the relationship between SF and liver diseases for providing guidance for future research.

iron  /  ferritin  /  hepatitis  /  liver cirrhosis  /  liver transplantation
Zhi-Lin Sha, Shao-Hua Song, Guo-Shan Ding. Research progress of relationship between serum ferritin and hepatic disease[J]. Medical Journal of Chinese People’s Liberation Army, 2021 , 46 (2) : 181 -185 . DOI: 10.11855/j.issn.0577-7402.2021.02.12
Funding
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  • National Natural Science Foundation of China(81671576)
  • Project of Shanghai Municipal Commission of Health and Family Planning(201640274)
Appendix
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Year 2021 volume 46 Issue 2
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191
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Article Info
doi: 10.11855/j.issn.0577-7402.2021.02.12
  • Receive Date：2020-04-21
  • Online Date：2025-12-26
  • Published：2021-02-28
Article Data
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History
  • Received：2020-04-21
  • Revised：2020-10-17
Funding
National Natural Science Foundation of China(81671576)
Project of Shanghai Municipal Commission of Health and Family Planning(201640274)
Affiliations
    Department of Organ Transplantation, Changzheng Hospital Affiliated to Naval Military Medical University, Shanghai 200003, China

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Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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