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Investigation of the aeroallergens spectrum and related risk factors in 388 patients with allergic rhinitis in Zhangjiakou area
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Rui Chen1, Ying Zhao1, Jing An1, Lin Zeng1, Gang Xue2, Hong-Ru Song1, Yu-Tuo Zhang1, *
Medical Journal of Chinese People’s Liberation Army | 2021, 46(2) : 149 - 155
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Medical Journal of Chinese People’s Liberation Army | 2021, 46(2): 149-155
Clinical Research
Investigation of the aeroallergens spectrum and related risk factors in 388 patients with allergic rhinitis in Zhangjiakou area
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Rui Chen1, Ying Zhao1, Jing An1, Lin Zeng1, Gang Xue2, Hong-Ru Song1, Yu-Tuo Zhang1, *
Affiliations
  • 1Institute of Pathogen Biology and Immunology, Hebei North University, Zhangjiakou, Hebei 075000, China
  • 2Department of Otolaryngology, Head and Neck Surgery, the First Affiliated Hospital of Hebei North University, Zhangjiakou, Hebei 075000, China
Published: 2021-02-28 doi: 10.11855/j.issn.0577-7402.2021.02.07
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Objective To investigate the distribution of inhaled allergens and analyze the related risk factors among allergic rhinitis (AR) patients in Zhangjiakou area. Methods Serum specific IgE antibody of inhaled allergens was detected in 532 suspected AR patients in the Department of Otolaryngology, Head and Neck Surgery of the First Affiliated Hospital of Hebei North University form April 2019 to August 2020. A total of 245 family members of outpatient and inpatient patients (except family members of respiratory department, dermatology department and otolaryngology department) in the same period were selected as the control group. AR questionnaire survey was conducted in the AR patients and control group, and the survey results were statistically analyzed. Results Of the 532 patients with suspected allergic rhinitis, 388 (72.9%) were positive for at least one allergen. The top three positivity rates of inhalation allergens were mugwort (89.9%), common ragweed (44.1%) and cat epithelium(21.4%) among the AR patients. In the single allergen positive patients, the mudwort has a much higher positive detection rate(86.0%). The positive degree of allergens was mainly distributed in class 2, class 3 and class 6 of mugwort, in class 1 of house dust and house dust mite, and in class 2 of other allergens. There were statistically significant differences in the allergen positive rate of AR patients in different months, regions and ages (P<0.05). The allergen positivity rate from July to September was significantly higher than that in other months, in bar-upper region was significantly higher than that in bar-lower region, and the positive rate of allergen gradually declined with the increase of age. The differences of allergens in ragweed, cat epithelium, house dust, house dust mite and streptomyces alternaria between genders of AR patients were statistically significant (P<0.05). Multivariate logistic analysis showed that previous allergies, parents with allergic rhinitis, history of asthma, secondhand smoke exposure, staying up late, age 3-24 years old were AR high-risk factors (OR>1), regular physical exercise was an effective protective factor for AR (OR<1). Conclusions The most common inhalation allergens in Zhangjiakou area are mugwort and common ragweed. The distribution of allergens is correlated with the month, region, and gender and age of the patients. Previous allergies, history of asthma, parents having allergic rhinitis, age and so on are risk factors for AR.

Zhangjiakou area  /  allergic rhinitis  /  allergens  /  risk factors
Rui Chen, Ying Zhao, Jing An, Lin Zeng, Gang Xue, Hong-Ru Song, Yu-Tuo Zhang. Investigation of the aeroallergens spectrum and related risk factors in 388 patients with allergic rhinitis in Zhangjiakou area[J]. Medical Journal of Chinese People’s Liberation Army, 2021 , 46 (2) : 149 -155 . DOI: 10.11855/j.issn.0577-7402.2021.02.07
  • Key Project of Science and Technology Research of Hebei North University(YB2018015)
  • Postgraduate Innovation Support Project of Hebei Province(CXZZSS2021129)
Year 2021 volume 46 Issue 2
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Article Info
doi: 10.11855/j.issn.0577-7402.2021.02.07
  • Receive Date:2020-10-05
  • Online Date:2025-12-26
  • Published:2021-02-28
Article Data
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History
  • Received:2020-10-05
  • Revised:2021-01-17
Funding
Key Project of Science and Technology Research of Hebei North University(YB2018015)
Postgraduate Innovation Support Project of Hebei Province(CXZZSS2021129)
Affiliations
    1Institute of Pathogen Biology and Immunology, Hebei North University, Zhangjiakou, Hebei 075000, China
    2Department of Otolaryngology, Head and Neck Surgery, the First Affiliated Hospital of Hebei North University, Zhangjiakou, Hebei 075000, China

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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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