Trauma-induced hypercoagulopathy is a hypercoagulable phenotype of trauma-induced coagulopathy (TIC) characterized by vascular endothelial injury, excessive release of procoagulants, hyperfibrinogenemia, platelet hyperactivity, anticoagulant pathways impairment and fibrinolysis shutdown. Recent studies have found that the incidence, mortality and disability rate of trauma-induced hypercoagulopathy increased significantly with the severity of trauma. Therefore, the People's Liberation Army Professional Committee of Critical Care Medicine and China Medical Education Association Professional Committee of Thrombosis, Hemostasis and Critical Care Medicine jointly formulated Chinese expert consensus on diagnosis and treatment of trauma-induced hypercoagulopathy published in Military Medical Research in April, 2021. In present paper, the main contents of the consensus were interpreted from the definition, pathophysiological mechanism, assessment, prevention, and treatment of trauma-induced hypercoagulopathy.

trauma  /  hypercoagulability  /  thrombosis  /  diagnosis  /  treatment  /  consensus