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Clinical research progress of male breast cancer and the research status in China
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Zi-Xing Wang1, Nian-Chang Wang2, Xiang-Yu Wang3, *
Medical Journal of Chinese People’s Liberation Army | 2021, 46(7) : 737 - 742
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Medical Journal of Chinese People’s Liberation Army | 2021, 46(7): 737-742
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Clinical research progress of male breast cancer and the research status in China
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Zi-Xing Wang1, Nian-Chang Wang2, Xiang-Yu Wang3, *
Affiliations
  • 1School of Basic Medical Sciences, Jining Medical University, Jining, Shandong 272067, China
  • 2Department of Cancer Prevention, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
  • 3Department of Breast Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Published: 2021-07-28 doi: 10.11855/j.issn.0577-7402.2021.07.15
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Male breast cancer (MBC) is a rare disease for which almost no prospective studies have focused on its diagnosis and treatment. MBC is more likely to be positive for hormone receptor while the ratio of triple negative and human epidermal growth factor receptor 2 (HER2) positive is very low. Most men have undergone radical mastectomy and modified radical mastectomy after diagnosis of breast cancer during past decades and sentinel lymph node biopsy has been gradually used in recent years. The indications of postoperative adjuvant radiotherapy refer to female breast cancer (FBC). Tamoxifen is the first choice of adjuvant endocrine therapy for MBC and chemotherapy can also improve MBC patients' prognosis. Anti-HER2 therapy is recommended for patients with high risks, though there is no definite evidence for its application. Data for the use of new drugs in MBC are lacking,whereas it may be a reasonable approach for metastatic MBC. In general, the overall prognosis of MBC is worse than FBC, but a few studies showed that MBC and FBC had similar survival rates after adjustment for demographic characteristics, disease stage, and treatment. Most of published articles are retrospective studies including small cohorts of MBC patients, which have been reviewed in this article. The review summarizes current data on the epidemiology of MBC, pathological and clinical characteristics, prognosis and treatment, and data published in our country during the past decade.

male breast cancer  /  pathology  /  treatment  /  prognosis
Zi-Xing Wang, Nian-Chang Wang, Xiang-Yu Wang. Clinical research progress of male breast cancer and the research status in China[J]. Medical Journal of Chinese People’s Liberation Army, 2021 , 46 (7) : 737 -742 . DOI: 10.11855/j.issn.0577-7402.2021.07.15
Year 2021 volume 46 Issue 7
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doi: 10.11855/j.issn.0577-7402.2021.07.15
  • Receive Date:2021-01-22
  • Online Date:2025-12-20
  • Published:2021-07-28
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History
  • Received:2021-01-22
  • Revised:2021-06-08
Affiliations
    1School of Basic Medical Sciences, Jining Medical University, Jining, Shandong 272067, China
    2Department of Cancer Prevention, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
    3Department of Breast Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China

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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
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Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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