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Objective To study the risk factors for extraesophageal symptoms in the patients with reflux esophagitis. Method One hundred and thirty-nine reflux esophagitis cases diagnosed by endoscophy and pH monitoring of the esophagus and hospitalized in Characteristic Medical Center of Strategic Support Army from March 2018 to November 2019. These cases were divided into positive or negative groups according to reflux symptom index (RSI) > or <13. Differences in gender, age, body mass index (BMI), smoking, drinking, emotional factors (anxiety and depression evaluation), reflux esophagitis microscopic classification,24-hour esophageal pH monitoring related index (Demeester index) were taking into account in logistical regression to identify the potential cause of reflux esophagitis. Results The positive group had higher age [(58.8±15.4) years], higher BMI (63%),higher anxiety (36%) and higher DeMeester (54%) than negative group [(52.8±11.7) years, 39%, 14%, 27% respectively], and the differences were statistically significant (P<0.05). There were no significant differences in gender, smoking, drinking, depression rate and endoscopic grade of reflux esophagitis between the two groups (P>0.05). Logistic multiple regression results showed that high BMI and positive DeMeester score were independent risk factors for patients with extrasoesophageal symptoms (OR=1.896, 95%CI 1.363-3.942, P<0.05; OR=6.868, 95%CI 1.648-18.087, P<0.01). Conclusions Higher BMI (overweight) and positive DeMeester score have predictive value for extraesophageal symptoms of the patients with reflux esophagitis, and they would increase the incidence of extraesophageal symptoms.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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