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Mitophagy is a selective form of autophagy that can selectively remove abnormal or redundant mitochondria to maintain the quality and function of mitochondria, so is regarded as an important regulation form of cell homeostasis. Stem cells are a type of cells with self-renewal, pluripotency and differentiation potential, and play a vital role in individual development,tissue renewal and certain diseases. Studies have shown that mitophagy is highly correlated with the self-renewal, pluripotency and differentiation of stem cells. The function and regulation mechanism of mitophagy in a variety of normal stem cells (embryonic stem cells, induced pluripotent stem cells, hematopoietic stem cells, mesenchymal stem cells, neural stem cells, cardiac stem cells)and cancer stem cells have been reviewed in present paper, so is to deeply understand the relationship between mitophagy and the biological functions of stem cells, and to provide a new theoretical reference for stem cell regulatory mechanisms and treatment strategies.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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