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Research progress of bile acid-intestinal flora and diarrhea-predominant irritable bowel syndrome
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Jin-Peng Li, Zhen-Zhen Liu, Gao-Fei Shen, Fei Zhu, Jun-Yi Zheng, Rui Huang*
Medical Journal of Chinese People’s Liberation Army | 2021, 46(12) : 1258 - 1262
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Medical Journal of Chinese People’s Liberation Army | 2021, 46(12): 1258-1262
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Research progress of bile acid-intestinal flora and diarrhea-predominant irritable bowel syndrome
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Jin-Peng Li, Zhen-Zhen Liu, Gao-Fei Shen, Fei Zhu, Jun-Yi Zheng, Rui Huang*
Affiliations
  • Department of Gastroenterology, Xi'an People's Hospital (Xi'an Fourth Hospital), Xi'an 710199, China
Published: 2021-12-28 doi: 10.11855/j.issn.0577-7402.2021.12.14
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Irritable bowel syndrome (IBS) is the most common functional bowel disease, and diarrhea-predominant IBS(IBS-D) is the most common type of IBS in our country. There are many causes of IBS, among which abnormal bile acid metabolism and intestinal flora disorder are the main pathogenic factors. Abnormal bile acid metabolism and intestinal flora disorders are found in patients with IBS-D. Intestinal flora is critical in the regulation of bile acid synthesis. Disorders of intestinal flora may lead to abnormal bile acid metabolism. Studies have pointed out that bile acid pathway (farnesoid X receptor, FXR) agonists can improve IBS-D symptoms by regulating receptor bile acid metabolism and intestinal flora. The interaction and corresponding mechanism of bile acid-intestinal flora and IBS-D were summarized in present paper.

irritable bowel syndrome  /  bile acid  /  intestinal flora
Jin-Peng Li, Zhen-Zhen Liu, Gao-Fei Shen, Fei Zhu, Jun-Yi Zheng, Rui Huang. Research progress of bile acid-intestinal flora and diarrhea-predominant irritable bowel syndrome[J]. Medical Journal of Chinese People’s Liberation Army, 2021 , 46 (12) : 1258 -1262 . DOI: 10.11855/j.issn.0577-7402.2021.12.14
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Year 2021 volume 46 Issue 12
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Article Info
doi: 10.11855/j.issn.0577-7402.2021.12.14
  • Receive Date：2021-04-25
  • Online Date：2025-12-18
  • Published：2021-12-28
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  • Received：2021-04-25
  • Revised：2021-10-09
Affiliations
    Department of Gastroenterology, Xi'an People's Hospital (Xi'an Fourth Hospital), Xi'an 710199, China

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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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