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Research progress of effect of exosomal microRNAs and long non-coding RNAs on breast cancer
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Xue Wan, Ting Ye, Jing-Yuan Li, Jia Feng, Dan Xie, Jin-Bo Liu*
Medical Journal of Chinese People’s Liberation Army | 2021, 46(12) : 1245 - 1250
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Medical Journal of Chinese People’s Liberation Army | 2021, 46(12): 1245-1250
• Review •
Research progress of effect of exosomal microRNAs and long non-coding RNAs on breast cancer
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Xue Wan, Ting Ye, Jing-Yuan Li, Jia Feng, Dan Xie, Jin-Bo Liu*
Affiliations
  • Department of Laboratory Medicine, the Af fi liated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China
Published: 2021-12-28 doi: 10.11855/j.issn.0577-7402.2021.12.12
Outline
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Exosomes are microcapsules with a diameter of 30-150 nm, which contain such active substances as proteins,lipids, metabolites, microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), and promote tumorigenesis and development by mediating intercellular communication and regulating tumor microenvironment. miRNAs and lncRNAs are the important components of non-coding RNAs, which play an important role in the occurrence and development of breast cancer mediated by exosomes. The present paper mainly summarized the role of exosomal miRNAs and lncRNAs derived from breast cancer cells in breast cancer progression, microenvironment and drug resistance, the effects of exosomal miRNAs and lncRNAs derived from breast cancer microenvironment on the development of breast cancer, and the clinical potential of exosomal miRNAs and lncRNAs as biomarkers in breast cancer.

breast cancer  /  exosomes  /  exosomal miRNAs  /  exosomal lncRNAs  /  tumor microenvironment
Xue Wan, Ting Ye, Jing-Yuan Li, Jia Feng, Dan Xie, Jin-Bo Liu. Research progress of effect of exosomal microRNAs and long non-coding RNAs on breast cancer[J]. Medical Journal of Chinese People’s Liberation Army, 2021 , 46 (12) : 1245 -1250 . DOI: 10.11855/j.issn.0577-7402.2021.12.12
Funding
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  • Doctoral Research Initiation Fund of the Affiliated Hospital of Southwest Medical University(19077)
  • Key Research and Development Project of Sichuan Province Science and Technology Plan(2019YFS0332)
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Year 2021 volume 46 Issue 12
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Article Info
doi: 10.11855/j.issn.0577-7402.2021.12.12
  • Receive Date：2020-12-28
  • Online Date：2025-12-18
  • Published：2021-12-28
Article Data
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History
  • Received：2020-12-28
  • Revised：2021-05-12
Funding
Doctoral Research Initiation Fund of the Affiliated Hospital of Southwest Medical University(19077)
Key Research and Development Project of Sichuan Province Science and Technology Plan(2019YFS0332)
Affiliations
    Department of Laboratory Medicine, the Af fi liated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China

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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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