Home Journals Articles Updates About
CN
image
收藏切换
Relationship between intramyocardial hemorrhage and adverse ventricular remodeling after myocardial infarction
收藏切换
PDF
Run-Du Chen1, 2, Ying-Qian Zhang1, Wei Tong1, Li-Bing Li3, Yuan-Bin Wu2, 3, Hao Zhou1, 2, Yun-Dai Chen1, *
Medical Journal of Chinese People’s Liberation Army | 2022, 47(2) : 186 - 191
Less
收藏切换
Medical Journal of Chinese People’s Liberation Army | 2022, 47(2): 186-191
• Review •
Relationship between intramyocardial hemorrhage and adverse ventricular remodeling after myocardial infarction
Full
Run-Du Chen1, 2, Ying-Qian Zhang1, Wei Tong1, Li-Bing Li3, Yuan-Bin Wu2, 3, Hao Zhou1, 2, Yun-Dai Chen1, *
Affiliations
  • 1Department of Cardiovascular Medicine, Chinese PLA General Hospital, Beijing 100853, China
  • 2Graduate School of Chinese PLA Medical College, Beijing 100853, China
  • 3Department of Cardiac and Vascular Surgery, the First Medical Center of Chinese PLA General Hospital, Beijing 100853, China
Published: 2022-02-28 doi: 10.11855/j.issn.0577-7402.2022.02.0186
Outline
收藏切换

Myocardial infarction (MI) is cardiomyocyte necrosis caused by myocardial ischemia and hypoxia, and is the leading cause of death and disability in the world. Although direct percutaneous coronary intervention (PCI) can restore epicardial coronary blood flow and reduce the mortality of MI, some patients with MI will still develop into chronic heart failure. As an important complication caused by reperfusion therapy, intramyocardial hemorrhage (IMH) is defined as red blood cell extravasation caused by severe microvascular injury, and can be used as an independent predictor of the adverse ventricular remodeling after myocardial infarction, which is the pathological basis of heart failure after myocardial infarction. At present, the main evaluation method for IMH is cardiac magnetic resonance imaging (MRI), especially the qualitative and quantitative evaluation of intracardial bleeding can be achieved by T2* sequence. It has been shown that iron deposition after degradation of IMH exacerbates the inflammatory response, leading to the aggregation of macrophages and secretion of matrix metalloproteinases, which are involved in subsequent adverse ventricular remodeling. The recent progress of clinical and basic research on the relationship between IMH and the adverse ventricular remodeling after MI are reviewed in present paper, hoping to be helpful for the prevention and treatment of IMH in the future.

intramyocardial hemorrhage  /  ischemia reperfusion injury  /  adverse ventricular remodeling
Run-Du Chen, Ying-Qian Zhang, Wei Tong, Li-Bing Li, Yuan-Bin Wu, Hao Zhou, Yun-Dai Chen. Relationship between intramyocardial hemorrhage and adverse ventricular remodeling after myocardial infarction[J]. Medical Journal of Chinese People’s Liberation Army, 2022 , 47 (2) : 186 -191 . DOI: 10.11855/j.issn.0577-7402.2022.02.0186
Funding
Less
  • National Natural Science Foundation for Distinguished Young Scholars(81800221)
  • National Major Scientific Equipment and Instruments Development Project(81827808)
Appendix
Less
Year 2022 volume 47 Issue 2
PDF
166
70
Cite this Article
BibTeX
Article Info
doi: 10.11855/j.issn.0577-7402.2022.02.0186
  • Receive Date：2021-09-06
  • Online Date：2025-12-17
  • Published：2022-02-28
Article Data
Affiliations
History
  • Received：2021-09-06
  • Accepted：2021-09-29
Funding
National Natural Science Foundation for Distinguished Young Scholars(81800221)
National Major Scientific Equipment and Instruments Development Project(81827808)
Affiliations
    1Department of Cardiovascular Medicine, Chinese PLA General Hospital, Beijing 100853, China
    2Graduate School of Chinese PLA Medical College, Beijing 100853, China
    3Department of Cardiac and Vascular Surgery, the First Medical Center of Chinese PLA General Hospital, Beijing 100853, China

Corresponding:

References
Share
https://castjournals.cast.org.cn/joweb/jfjyxzz/EN/10.11855/j.issn.0577-7402.2022.02.0186
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT
Links
Articles
Latest Articles
Most Read
Collections
Updates
Events
News
Multimedia
About
About Us
Contact
No. 86 Xueyuan South Road, Haidian District, Beijing
100081
010-62199257
qkjq@cast.org.cn

Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House