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Effect of analgesic drugs on acute gastrointestinal injury in critically ill patients
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Yun Yan, Yu Chen, Xi-Jing Zhang*
Medical Journal of Chinese People’s Liberation Army | 2022, 47(3) : 299 - 304
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Medical Journal of Chinese People’s Liberation Army | 2022, 47(3): 299-304
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Effect of analgesic drugs on acute gastrointestinal injury in critically ill patients
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Yun Yan, Yu Chen, Xi-Jing Zhang*
Affiliations
  • Department of Critical Care Medicine, Xijing Hospital, Air Force Medical University, Xi’an 710000, China
Published: 2022-03-28 doi: 10.11855/j.issn.0577-7402.2022.03.0299
Outline
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Gastrointestinal dysfunction is one of the initiating factors for multiple organ failure. The European Society of Intensive Care Medicine (ESICM) proposed the definition of acute gastrointestinal injury (AGI) to describe dysfunction of the gastrointestinal tract in critically ill patients. AGI occurs frequently in the intensive care unit (ICU) and associates with clinical outcomes of ICU patients. The incidence of pain is high in the ICU, and analgesic drugs can significantly improve the prognosis of patients. But the administration of analgesic drugs is an important factor affecting gastrointestinal function. So, in order to prevent AGI in high-risk patients, both analgesic needs and low impact on gastrointestinal function need to be taken into account before choices of opioids are finalized. This review briefly summarizes the mechanisms of AGI in ICU patients and the studies related to the effects of analgesics on gastrointestinal motility and barrier in ICU patients with opioids as the core, providing a reference for clinical selection.

acute gastrointestinal injury  /  analgesics  /  intensive care unit  /  opioids
Yun Yan, Yu Chen, Xi-Jing Zhang. Effect of analgesic drugs on acute gastrointestinal injury in critically ill patients[J]. Medical Journal of Chinese People’s Liberation Army, 2022 , 47 (3) : 299 -304 . DOI: 10.11855/j.issn.0577-7402.2022.03.0299
  • National Natural Science Foundation of China(81871603)
  • Key Research and Development Program of Shaanxi Province(2020ZDXM-SF-002)
Year 2022 volume 47 Issue 3
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Article Info
doi: 10.11855/j.issn.0577-7402.2022.03.0299
  • Receive Date:2021-05-31
  • Online Date:2025-12-17
  • Published:2022-03-28
Article Data
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History
  • Received:2021-05-31
  • Accepted:2021-07-28
Funding
National Natural Science Foundation of China(81871603)
Key Research and Development Program of Shaanxi Province(2020ZDXM-SF-002)
Affiliations
    Department of Critical Care Medicine, Xijing Hospital, Air Force Medical University, Xi’an 710000, China

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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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