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Research progress on the pathogenesis of hypertriglyceridemia-related acute pancreatitis
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Chi Wang1, Li-Fang Duan1, Xiao-Fan Xu2, Hong Zhang1, 3, *
Medical Journal of Chinese People’s Liberation Army | 2022, 47(5) : 500 - 505
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Medical Journal of Chinese People’s Liberation Army | 2022, 47(5): 500-505
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Research progress on the pathogenesis of hypertriglyceridemia-related acute pancreatitis
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Chi Wang1, Li-Fang Duan1, Xiao-Fan Xu2, Hong Zhang1, 3, *
Affiliations
  • 1Basic Medical Academy, Shaanxi University of Traditional Chinese Medicine, Xianyang, Shaanxi 712046, China
  • 2Medical Experiment Center, Shaanxi University of Traditional Chinese Medicine, Xianyang, Shaanxi 712046, China
  • 3Shaanxi International Cooperation Base/International Joint Research Center for Prevention and Treatment of Immune Inflammation Related Diseases with Traditional Chinese Medicine, Shaanxi University of Traditional Chinese Medicine, Xianyang, Shaanxi 712046, China
Published: 2022-05-28 doi: 10.11855/j.issn.0577-7402.2022.05.0500
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With the change of people's lifestyle and diet structure, hypertriglyceridemia (HTG) has gradually become an important factor causing or aggravating acute pancreatitis (AP). Some studies have pointed out that HTG has become the second major factor of AP following biliary diseases. The concept of hypertriglyceridemic-related acute pancreatitis (HTG-AP) has been put forward, and a large number of studies have been carried out on its mechanism. However, the mechanism of hypertriglyceridemia involved in the progression of AP is still unclear, leading to the lack of specific targets for treatment. This article reviews the pathogenesis of HTG-AP, including excessive free fatty acids (FFA)-induced oxidative stress, Ca2+ overload, endoplasmic reticulum stress, microcirculatory disturbance, etc.

hypertriglyceridemia  /  acute pancreatitis  /  pathogenesis
Chi Wang, Li-Fang Duan, Xiao-Fan Xu, Hong Zhang. Research progress on the pathogenesis of hypertriglyceridemia-related acute pancreatitis[J]. Medical Journal of Chinese People’s Liberation Army, 2022 , 47 (5) : 500 -505 . DOI: 10.11855/j.issn.0577-7402.2022.05.0500
Funding
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  • National Natural Science Foundation of China(81603420)
  • Natural Science Foundation of Shaanxi Province(2017JM8076)
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Year 2022 volume 47 Issue 5
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Article Info
doi: 10.11855/j.issn.0577-7402.2022.05.0500
  • Receive Date：2021-07-19
  • Online Date：2025-12-17
  • Published：2022-05-28
Article Data
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History
  • Received：2021-07-19
  • Accepted：2021-09-29
Funding
National Natural Science Foundation of China(81603420)
Natural Science Foundation of Shaanxi Province(2017JM8076)
Affiliations
    1Basic Medical Academy, Shaanxi University of Traditional Chinese Medicine, Xianyang, Shaanxi 712046, China
    2Medical Experiment Center, Shaanxi University of Traditional Chinese Medicine, Xianyang, Shaanxi 712046, China
    3Shaanxi International Cooperation Base/International Joint Research Center for Prevention and Treatment of Immune Inflammation Related Diseases with Traditional Chinese Medicine, Shaanxi University of Traditional Chinese Medicine, Xianyang, Shaanxi 712046, China

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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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