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Long non-coding RNA (lncRNA) is a kind of non-protein coding RNA with a sequence length of more than 200 bp. It regulates the epigenetic characters of organisms by regulating pre-transcription, transcription, and post-translation modification. Atherosclerosis is a kind of vascular disease that gradually narrowed and blocked due to the atherosclerotic lesions in the large and middle arteries. The mechanisms of initiation and progression of atherosclerosis can be summarized as "Injury-Response" doctrine, which involves lipid deposition, intimal inflammation, cell proliferation and apoptosis. It is reported that lncRNA can regulate the "Injury-Response" process by regulating different gene and molecular expression. Here, we provide a mechanistic review of how lncRNA regulate the "Injury-Response", which will provide reference for the future basic research and clinical diagnosis and treatment.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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