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Objective To investigate the clinical characteristics and related factors of patients with fat liquefaction of approach wounds after thoracic endovascular aortic repair (TEVAR). Methods The clinical data of 939 patients undergone TEVAR from August 2005 to June 2021 were consecutively enrolled in present study, and divided into fat liquefaction group (n=73)and non-fat liquefaction group (n=866) according to whether fat liquefaction occurs in the wound after operation. The clinical characteristics such as age, gender, overweight, past medical history, imaging findings, anemia, renal insufficiency, approach and laboratory indicators were compared between the two groups. Univariate and multivariate binary logistic regression were performed to analyze the factors associated with fat liquefaction of approach wounds. Results No significant difference existed between the two groups in age, gender, history of hypertension, coronary heart disease, diabetes, combined with pleural effusion and other clinical characteristics (P>0.05). The proportions of overweight and renal insufficiency were higher in fat liquefaction group than those in non-fat liquefaction group with significant differences (82.8% vs. 67.4%, P=0.011; 22.9% vs. 13.3%, P=0.028). While the levels of creatine kinase isoenzyme [10.00(7.00, 14.00) U/L vs. 11.00(8.00, 15.00) U/L, P=0.018] and hemoglobin [(130.64±17.33) g/L vs. (134.96±16.42) g/L, P=0.032], and the proportion of patients with femoral artery puncture (4.2% vs. 16.1%, P=0.007) were lower in fat liquefaction group than those in non-fat liquefaction group with statistical significance (P<0.05). Multivariate binary logistic regression analysis showed that overweight (OR=2.226, 95%CI 1.135-4.364, P=0.020) and renal insufficiency (OR=2.116,95%CI 1.119-4.003, P=0.021) were the independent risk factors for fat liquefaction in approach wounds after TEVAR. Femoral artery puncture (OR=0.273, 95%CI 0.084-0.889, P=0.031) was an independent protective factor for fat liquefaction of surgical approach after TEVAR. Conclusion Overweight combined with renal insufficiency can increase the risk of fat liquefaction in approach wounds after TEVAR, and femoral artery puncture may reduce such risk.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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