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Growth hormone (GH) and insulin-like growth factor 1 (IGF-1) are the important endocrine hormones for human, and their associated diseases (e. g. acromegaly and growth hormone deficiency) can lead to obviously increased morbidity and mortality secondary to cardiovascular, cerebrovascular and respiratory diseases. Clinically, the determination and closely monitoring of serum GH and IGF-1 are important means for diagnosing, assessing curative effect and formulating post-treatment follow-up plans of such diseases, and have received extensive concern from clinicians. Although the levels of serum GH and IGF-1 are consistent in most cases, more and more studies have reported that the results of serum GH and IGF-1 are unreasonable or even contradictory. Therefore, in the conditions of inconsistent serum GH and IGF-1 levels, reliable biochemical criteria for assessing disease status and control degree are currently controversial, and their rational interpretation remains a clinical challenge. In present paper, the influence of serum GH and IGF-1 detection methods, physiological and pathological states, and drugs on the detection results and the possible reasons or mechanisms are explained in detail, and proposes that it is necessary to carefully sort out the factors that may lead to unreasonable results in clinic, in order to judge the detection results more accurately and conduct appropriate diagnosis and treatment of the related diseases.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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